Pancreatic islet cell ƙari

Ciwon ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta shine ƙwayar ƙwayar ƙwayar ƙwayar cuta wanda ke farawa daga nau'in kwayar halitta da ake kira islet cell.

A cikin ƙoshin lafiya, ƙwayoyin da ake kira ƙwayoyin rai suna haifar da homonin da ke tsara ayyukan jiki da yawa. Wadannan sun hada da matakin sikarin jini da samar da asid ciki.

Tumoshin da ke tashi daga ƙwayoyin tsibirin na pancreas suma na iya haifar da nau'o'in homon, wanda zai haifar da takamaiman alamun.

Tumwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta na iya zama marasa ciwo (mara kyau) ko cutar kansa (mugu).

Orsananan ƙwayoyin cuta sun haɗa da:

• Gastrinoma (Ciwon Zollinger-Ellison)
• Glucagonoma
• Insulinoma
• Somatostatinoma
  
• VIPoma (Ciwon Verner-Morrison)

Tarihin dangi na endoprine neoplasia dayawa, nau'ikan I (MEN I) shine haɗarin haɗari don ci gaba da ciwace-ciwacen tsirrai.

Kwayar cututtukan sun dogara da wane ƙwayar hormone ne ake samar da kumburi.

Misali, insulinomas na samar da insulin, wanda ke rage matakin suga a cikin jini. Kwayar cutar na iya haɗawa da:

• Jin kasala ko rauni
• Girgiza ko gumi
• Ciwon kai
• Yunwa
• Ciwo, damuwa, ko jin haushi
• Tunani mara kyau ko jin damuwa
• Gani biyu ko gani
• Saurin ko bugun zuciya

Idan matakin sikarin jininka ya yi kasa sosai, za ka iya suma, ka kamu, ko ma ka shiga cikin mawuyacin hali.

Gastrinomas suna sanya gastrin hormone, wanda ke gaya wa jiki yin acid na ciki. Kwayar cutar na iya haɗawa da:

• Ciwon ciki
• Gudawa
• Ulcer a cikin ciki da ƙananan hanji
• Jinin amai (lokaci-lokaci)

Glucagonomas suna sanya glucagon hormone, wanda ke taimakawa jiki ya ɗaga matakin sukarin jini. Kwayar cutar na iya haɗawa da:

• Ciwon suga
• Red, blistery rash a cikin makwancin gwaiwa ko gindi
• Rage nauyi
• Yawan yin fitsari da kishirwa

Somatostatinomas sunyi hormone somatostatin. Kwayar cutar na iya haɗawa da:

• Hawan jini mai yawa
• Duwatsu masu tsakuwa
• Bayyanar launin rawaya ga fata, da idanu
• Rage nauyi
• Gudawa tare da kumburin kursiyi mara ƙamshi

VIPomas suna yin peptide na hanji (VIP) na kwayar cutar wanda ke da hannu cikin kiyaye salts, sodium, potassium da sauran ma'adanai a cikin hanyar GI. VIPomas na iya haifar da:

• Tsananin gudawa wanda ka iya haifar da rashin ruwa a jiki
• Levelsananan matakan potassium, da yawan ƙwayoyin calcium
• Ciwon ciki
• Rage nauyi

Mai ba da lafiyar ku zai ɗauki tarihin lafiyar ku ya yi gwajin jiki.

Gwajin jini na iya bambanta, dangane da alamun, amma na iya haɗawa da:

• Azumin glucose mai sauri
• Matsayin Gastrin
• Gwajin haƙuri na Glucose
• Gwajin gwaji don ɓoyewa
• Matakan glucagon jini
• Sinadarin insulin na jini C-peptide
• Matsayin insulin na jini
• Azumin magani somatostatin matakin
• Maganin ƙwayar peptide na hanji (VIP)

Za'a iya yin gwajin hoto:

• CT scan na ciki
• Ciki duban dan tayi
• Endoscopic duban dan tayi
• MRI na ciki

Hakanan za'a iya ɗaukar samfurin jini daga jijiya a cikin pancreas don gwaji.

Wani lokaci, ana buƙatar tiyata don bincika da magance wannan yanayin. A yayin wannan aikin, likitan likita yana nazarin pancreas da hannu kuma tare da duban dan tayi.

Yin jiyya ya dogara da nau'in ciwace-ciwacen ƙwayoyin cuta da kuma idan yana da cutar kansa.

Ciwan daji na kansar na iya girma cikin sauri kuma yaɗu zuwa sauran gabobi. Wataƙila ba za a iya magance su ba. Sau da yawa ana cire ƙwayoyi tare da tiyata, idan zai yiwu.

Idan kwayoyin cutar kansa suka bazu zuwa hanta, ana iya cire wani ɓangare na hanta, idan zai yiwu. Idan ciwon daji ya yadu, ana iya amfani da chemotherapy don gwadawa da rage jijiyoyin.

Idan yawan kwayar halittar hormones ke haifar da cututtuka, zaka iya karɓar magunguna don magance tasirin su. Misali, tare da gastrinomas, yawan fitowar gastrin yana haifar da yawan acid a ciki. Magungunan da ke toshe fitowar ruwan ciki na ciki na iya rage bayyanar cututtuka.

Kuna iya sauƙaƙa damuwar rashin lafiya ta hanyar haɗuwa da ƙungiyar tallafawa kansa. Yin tarayya tare da wasu waɗanda suke da masaniya da matsaloli na yau da kullun na iya taimaka muku kada ku ji ku kaɗai.

Kuna iya warkewa idan an cire ƙwayoyin cutar ta hanyar tiyata kafin su bazu zuwa wasu gabobin. Idan ciwace-ciwacen daji ne, ana iya amfani da chemotherapy, amma yawanci ba zai iya warkar da mutane ba.

Matsaloli masu barazanar rai (kamar ƙarancin sukari a cikin jini) na iya faruwa saboda yawan haɓakar hormone, ko kuma idan kansar ta bazu cikin jiki.

Matsalolin wadannan cututtukan sun hada da:

• Ciwon suga
• Rikicin Hormon (idan ƙari ya saki wasu nau'ikan hormones)
• Sugararancin sukari mai ƙarfi (daga insulinomas)
• Ulananan ciwo a cikin ciki da ƙananan hanji (daga gastrinomas)
• Yada ƙari zuwa hanta

Kira mai ba ku sabis idan kun ci gaba bayyanar cututtuka na waɗannan ciwace-ciwacen, musamman idan kuna da tarihin iyali na MAZA I.

Babu sanannun rigakafin ga waɗannan marurai.

Ciwon daji - pancreas; Ciwon daji - pancreatic; Ciwon daji na Pancreatic; Ciwan ƙwayoyin Islet; Islet na Langerhans ƙari; Neuroendocrine ƙari; Peptic ulcer - ƙwayar ƙwayar ƙwayar ƙwayar cuta; Hypoglycemia - ƙwayar ƙwayar ƙwayar cuta; Ciwon Zollinger-Ellison; Ciwon Verner-Morrison; Gastrinoma; Insulinoma; VIPoma; Somatostatinoma; Glucagonoma

• Endocrine gland
• Pancreas

Foster DS, Norton JA. Gudanar da cututtukan kwayar cutar kanjamau ban da gastrinoma. A cikin: Cameron AM, Cameron JL, eds. Far Mashi na Yanzu. 13th ed. Philadelphia, PA: Elsevier; 2020: 581-584.

Yanar gizo Cibiyar Cancer ta Kasa. Pancreatic cancer cancer (PDQ) - fasalin ƙwararrun masu kiwon lafiya. www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq. An sabunta Janairu 2, 2020. An shiga 25 ga Fabrairu, 2020.

Yanar gizo Yanar Gizon Cutar Kanjamau ta Kasa. NCCN jagororin aikin likita a cikin ilimin ilimin ilimin halittar jiki (jagororin NCCN). Neuroendocrine da adrenal ƙari. Sigar 1.2019. www.nccn.org/professionals/physician_gls/pdf/neuroendocrine.pdf. An sabunta Maris 5, 2019. Iso zuwa Fabrairu 25, 2020.

Yanar gizo Yanar Gizon Cutar Kanjamau ta Kasa. NCCN jagororin marasa lafiya. Neuroendocrine ƙari. 2018. www.nccn.org/patients/guidelines/content/PDF/neuroendocrine-patient.pdf.