Abin da kuke Bukatar Ku sani Game da MTHFR Gene

Wadatacce

• Bambancin canji MTHFR
• Kwayar cututtukan maye gurbi na MTHFR
• Gwaji don maye gurbi na MTHFR
• Jiyya don abubuwan da suka shafi lafiya
• Matsaloli a ciki
• Supplementarin ƙari
• Abincin abinci
• Takeaway

Mun haɗa da kayayyakin da muke tsammanin suna da amfani ga masu karatu. Idan ka siya ta hanyoyin yanar gizo a wannan shafin, zamu iya samun ƙaramin kwamiti. Ga tsarinmu.

Menene MTHFR?

Wataƙila kun ga taƙaitawar "MTHFR" ta bayyana a cikin labaran kiwon lafiya na kwanan nan. Yana iya zama kamar kalma ce ta la'ana a kallon farko, amma a zahiri yana nuni ne da maye gurbi na kwayar halitta.

MTHFR yana tsaye methylenetetrahydrofolate reductase. Ana samun kulawa ne saboda canjin kwayar halitta wanda zai iya haifar da babban matakin homocysteine ​​a cikin jini da ƙananan matakan fure da sauran bitamin.

Akwai damuwa cewa wasu al'amuran kiwon lafiya suna haɗuwa da maye gurbin MTHFR, don haka gwaji ya zama mafi mahimmanci a cikin shekaru.

Bambancin canji MTHFR

Kuna iya samun maye gurbi ɗaya ko biyu - ko ba haka ba - akan kwayar MTHFR. Wadannan sauye-sauye galibi ana kiransu da canje-canje. Bambanci wani sashi ne na DNA na kwayar halitta wanda ya sha bamban, ko ya bambanta, daga mutum zuwa mutum.

Samun bambance-bambancen guda - heterozygous - da ƙila zai iya taimakawa ga al'amuran kiwon lafiya. Wasu mutane sun gaskata samun maye gurbi sau biyu - homozygous - na iya haifar da matsaloli masu tsanani. Akwai bambance-bambancen guda biyu, ko nau'i, na maye gurbi wanda zai iya faruwa akan kwayar halittar MTHFR.

Takamaiman bambance-bambancen karatu sune:

• C677T. Kimanin kashi 30 zuwa 40 na yawan jama'ar Amurka na iya samun maye gurbi a yanayin kwayar halitta C677T. Kusan kashi 25 cikin 100 na mutanen asalin Hispaniki, da kashi 10 zuwa 15 na zuriyar Caucasian, suna yin luwadi ne saboda wannan bambancin.
• A1298C. Akwai iyakance bincike game da wannan bambancin. Karatuttukan da ake samu gaba daya ya danganta ne da yanayin kasa ko kabila. Misali, nazarin shekara ta 2004 ya ta'allaka ne akan masu bada jini na 120 na al'adun Irish. Daga cikin masu ba da gudummawar, kashi 56, ko 46.7 bisa ɗari, sun kasance masu ɗauke da wannan bambancin, kuma kashi 11, ko 14.2 cikin 100, sun yi luwadi.
• Hakanan yana yiwuwa a sayi duka maye gurbi na C677T da A1298C, wanda shine kwafin kowane ɗayansu.

Canjin kwayar halitta an gaji ta, wanda ke nufin kun samo ta daga iyayenku. A lokacin ɗaukar ciki, kun karɓi kwafin kwayar MTHFR ɗaya daga kowane mahaifa. Idan dukansu suna da maye gurbi, haɗarin samun maye gurɓin homozygous ya fi girma.

Kwayar cututtukan maye gurbi na MTHFR

Kwayar cutar ta bambanta daga mutum zuwa mutum kuma daga bambancin zuwa bambancin. Idan kayi saurin bincike na intanet, da alama zaku sami rukunin yanar gizo da yawa suna da'awar MTHFR kai tsaye yana haifar da yanayi da yawa.

Ka tuna cewa bincike game da MTHFR da tasirinsa yana ci gaba. Shaidun da ke danganta yawancin waɗannan yanayin kiwon lafiyar zuwa MTHFR a halin yanzu basu da shi ko an ƙi yarda da su.

Zai fi wataƙila, sai dai idan kuna da matsaloli ko kuma an yi gwajin gwaji, ba za ku taɓa sanin matsayin ku na maye gurbi na MTHFR ba.

Yanayin da aka gabatar don haɗuwa da MTHFR sun haɗa da:

• cututtuka na zuciya da jijiyoyin jini (musanya jini, bugun jini, embolism, da ciwon zuciya)
• damuwa
• damuwa
• cututtukan bipolar
• schizophrenia
• ciwon hanji
• m cutar sankarau
• ciwo mai tsanani da gajiya
• ciwon jijiya
• ƙaura
• maimaitawar ciki a cikin mata masu haihuwa
• ciki tare da lahani na bututu, kamar spina bifida da anencephaly

Ara koyo game da samun ciki mai nasara tare da MTHFR.

Mai yiwuwa haɗarin ya karu idan mutum yana da nau'ikan jinsin guda biyu ko kuma yana da kama da haɗuwa ga maye gurbin MTHFR

Gwaji don maye gurbi na MTHFR

Kungiyoyin kiwon lafiya daban-daban - gami da Kwalejin Obstetricians da Gynecologists na Amurka, Kwalejin Masana Bayanai na Amurka, Kwalejin Kimiyyar Halitta ta Amurka, da Associationungiyar Zuciya ta Amurka - ba da shawarar gwaji don bambance-bambancen ba sai dai idan mutum ma yana da matakan homocysteine ​​sosai ko wasu alamun kiwon lafiya.

Duk da haka, ƙila kuna da sha'awar gano matsayin ku na MTHFR. Yi la'akari da ziyartar likitan ku kuma tattauna fa'idodi da raunin gwajin.

Yi la'akari da cewa ƙila inshorarku ba za ta rufe gwajin kwayar halitta ba. Kira kamfanin dako idan kana tunanin yin gwaji don tambaya game da tsada.

Wasu kayan aikin gwajin kwayar halitta a gida suna ba da kariya don MTHFR kuma. Misalan sun hada da:

• 23andMe sanannen zaɓi ne wanda ke ba da asalin halittar jini da bayanin kiwon lafiya. Hakanan bashi da tsada ($ 200). Don yin wannan gwajin, za ku saka miyau a cikin bututu kuma ku aika ta imel zuwa gidan gwaje-gwaje. Sakamako yana ɗaukar makonni shida zuwa takwas.
• Gida na MTHFR ($ 150) wani zaɓi ne wanda ke mai da hankali kan maye gurbi. Gwajin an yi shi ne ta hanyar tattara DNA daga cikin kuncinku tare da swabs. Bayan jigilar samfurin, sakamakon yana ɗaukar sati ɗaya zuwa biyu.

Jiyya don abubuwan da suka shafi lafiya

Samun bambancin MTHFR ba yana nufin kuna buƙatar magani. Zai iya nufin kawai kuna buƙatar ɗaukar ƙarin bitamin B.

Ana buƙatar jiyya yawanci lokacin da kake da matakan homocysteine ​​sosai, kusan koyaushe sama da matakin da aka danganta ga yawancin nau'ikan MTHFR. Dole ne likitanku ya yi watsi da wasu dalilai masu yiwuwa na ƙara yawan homocysteine, wanda zai iya faruwa tare da ko ba tare da bambance-bambancen MTHFR ba.

Sauran dalilan babban homocysteine ​​sun hada da:

• hypothyroidism
• yanayi kamar ciwon suga, hauhawar cholesterol, da hawan jini
• kiba da rashin aiki
• wasu magunguna, kamar atorvastatin, fenofibrate, methotrexate, da nicotinic acid

Daga can, maganin zai dogara ne akan dalilin kuma ba lallai bane yayi la'akari da MTHFR. Banda shine lokacin da aka gano ku tare da duk waɗannan sharuɗɗan yanayi a lokaci guda:

• matakan homocysteine
• tabbataccen maye gurbi MTHFR
• karancin bitamin a cikin fure, choline, ko bitamin B-12, B-6, ko riboflavin

A waɗannan lokuta, likitanku na iya ba da shawarar ƙarin don magance rashi tare da magunguna ko magunguna don magance takamaiman yanayin kiwon lafiya.

Mutanen da ke da maye gurbi na MTHFR suna iya son ɗaukar matakan kariya don rage matakan homocysteine ​​ɗin su. Measureaya daga cikin matakan rigakafin shine canza wasu zaɓuɓɓukan rayuwa, wanda na iya taimakawa ba tare da amfani da magunguna ba. Misalan sun hada da:

• daina shan taba, idan kun sha taba
• samun isasshen motsa jiki
• cin abinci mai kyau, daidaitaccen abinci

Matsaloli a ciki

Rashin ɓarkewar yanayi da lahani na jijiyoyin jiki suna iya haɗuwa da MTHFR. Cibiyar Bayar da Bayani game da Cututtuka na Halitta da Rare ta ce nazarin ya ba da shawarar cewa matan da ke da nau'ikan C677T guda biyu suna cikin haɗarin samun ɗa mai nakasar bututu.

Wani bincike na shekara ta 2006 ya kalli matan da ke da tarihin yawan zubar ciki. Ya gano cewa kashi 59 cikin 100 daga cikinsu suna da maye gurbi da yawa, ciki har da MTHFR, wanda ke da alaƙa da daskarewar jini, a kan kashi 10 cikin 100 na mata ne kawai a rukunin kulawar.

Yi magana da likitanka game da gwaji idan ɗayan yanayi masu zuwa ya shafi ka:

• Kun fuskanci ɓarna da dama da ba a bayyana ba.
• Kuna da ɗa da nakasar bututu.
• Kun san kuna da maye gurbin MTHFR, kuma kuna da ciki.

Kodayake akwai ƙaramin shaida don tallafawa, wasu likitocin sun ba da shawarar shan magunguna masu ɗauke jini. Hakanan ana iya ba da shawarar ƙarin supplementarin folate.

Supplementarin ƙari

Mutuwar kwayar MTHFR ta hana yadda jiki ke sarrafa folic acid da sauran mahimman bitamin na B. Canza ƙarin wannan sinadarin gina jiki yana da damar mai da hankali ga magance tasirin sa.

Folic acid haƙiƙa ɗan adam ne wanda aka kera shi na fure, wani irin abinci mai ci wanda ake samu a cikin abinci. Formaukar nau'in fure mai samuwa - methylated folate - na iya taimakawa jikinka ɗaukar shi da sauƙi.

Mafi yawan mutane ana karfafa musu gwiwa su sha kwayar cuta mai yawan kwayoyi wacce ke dauke da a kalla miligrams 0.4 na folic acid a kowace rana.

Ba a ƙarfafa mata masu juna biyu don canza bitamin na lokacin haihuwa ko kulawa dangane da matsayin MTHFR kawai. Wannan yana nufin shan mizanin gwargwadon miligram 0.6 na folic acid a kullum.

Mata da ke da tarihin lahani na bututun hanji ya kamata suyi magana da likitansu don takamaiman shawarwari.

Multivitamins dauke da methylated folate sun hada da:

• Abubuwan Garkuwa na Thorne 2 / Day
• Smarty Wando Adult Complete
• Mama Bird mai ciki kafin ta haihu

Yi magana da likitanka kafin canza bitamin da kari. Wasu na iya tsoma baki tare da wasu magunguna ko jiyya da kuke karɓa.

Hakanan likitan ku na iya ba da shawarar bitamin da aka ba da magani wanda ya ƙunshi furolate da folic acid. Dogaro da inshorar ku, farashin waɗannan zaɓuɓɓukan na iya bambanta idan aka kwatanta da nau'ikan kan-kanti.

Abincin abinci

Cin abinci mai wadataccen ɗanɗano na iya taimakawa ta halitta tallafawa matakanku na wannan mahimmin bitamin. Koyaya, ƙarin zai iya zama dole.

Kyakkyawan zaɓin abinci sun haɗa da:

• sunadarai kamar dafaffun wake, da wake, da lentil
• kayan lambu kamar alayyafo, bishiyar asparagus, latas, beets, broccoli, masara, Brussels sprouts, da bok choy
• 'Ya'yan itãcen marmari kamar gandun daji, zuma, ayaba, berriesaberriesan bishiyar ɓaure,' ya'yan inabi, da kuma strawberries
• ruwan 'ya'yan itace kamar lemu, abarba mai gwangwani,' ya'yan inabi, tumatir, ko sauran ruwan 'ya'yan itace
• man gyada
• 'ya'yan sunflower

Mutanen da ke da maye gurbi na MTHFR na iya so su guji abincin da ke ɗauke da nau'in roba, folic acid - kodayake shaidar ba ta bayyana ba cewa hakan ya zama dole ko amfani.

Tabbatar da bincika tambari, saboda ana ƙara wannan bitamin a cikin hatsi masu wadata da yawa, kamar taliya, hatsi, burodi, da fulawar da aka samar ta kasuwanci.

Ara koyo game da banbanci tsakanin folate da folic acid.

Takeaway

Matsayin ku na MTHFR na iya ko bazai shafar lafiyar ku ba. Ana buƙatar ƙarin bincike don ƙayyade tasirin gaske, idan akwai, hade da bambance-bambancen karatu.

Bugu da ƙari, yawancin kungiyoyin kiwon lafiya da ake girmamawa ba sa ba da shawarar gwaji don wannan maye gurbi, musamman ba tare da wasu alamun likita ba. Yi magana da likitanka game da fa'idodi da haɗarin gwaji, da kuma duk wasu abubuwan damuwar da kake da su.

Ci gaba da cin abinci mai kyau, motsa jiki, da aiwatar da wasu halaye masu kyau na rayuwa don tallafawa ƙoshin lafiyar ku.