Tsarin lissafi na Gleason

Ana bincikar cutar kansar mafitsara bayan an yi gwaji. Takenaya ko fiye samfurorin nama ana ɗauke su daga prostate kuma a binciko su ta hanyar microscope.

Tsarin maki na Gleason yana nuni ne da yadda mahaukacin kwayoyin cutar sankarar kurarraji suke kallo da kuma yiwuwar cutar kansa zata ci gaba da yaduwa. Matsakaicin ƙananan Gleason yana nufin cewa ciwon daji yana girma a hankali kuma ba mai rikici ba.

Mataki na farko a tantance ƙimar Gleason shine sanin ƙimar Gleason.

1. Lokacin kallon kwayoyin halitta a karkashin madubin likita, likita ya sanya lamba (ko maki) ga kwayoyin cutar kanjamau tsakanin 1 da 5.
2. Wannan darasin ya ta'allaka ne akan yadda kwayoyin halitta suke bayyana. Hanyar 1 tana nufin cewa ƙwayoyin suna kama da ƙwayoyin prostate na al'ada. Darasi na 5 yana nufin cewa ƙwayoyin suna da banbanci da ƙwayoyin prostate na al'ada.
3. Yawancin cututtukan prostate suna ƙunshe da ƙwayoyin da suke maki daban. Don haka ana amfani da maki biyu da aka fi sani.
4. Sakamakon Gleason an ƙaddara shi ta hanyar ƙara maki biyu da aka fi sani. Misali, mafi yawan kwayar halittar da ke cikin samfurin nama na iya zama kwaya ta 3, sa'annan kwayoyin na 4 na biye. Sakamakon Gleason don wannan samfurin zai zama 7.

Lambobi mafi girma suna nuna saurin ciwon daji wanda zai iya yaɗuwa.

A halin yanzu mafi ƙarancin maki da aka sanya wa ƙari shi ne aji 3. Makarantun da ke ƙasa da 3 suna nuna al'ada zuwa kusa da ƙwayoyin al'ada. Yawancin cututtukan daji suna da maki Gleason (jimlar maki biyu da aka fi sani) tsakanin 6 (Gleason na 3 + 3) da 7 (Gleason na 3 + 4 ko 4 + 3).

Wani lokaci, zai yi wuya a iya hasashen yadda mutane za su yi daidai da ƙimar Gleason su kaɗai.

• Misali, ana iya sanya cutar ku a Gleason ci 7 idan maki biyu da suka fi yawa sune 3 da 4. 7 na iya zuwa ko dai a ƙara 3 + 4 ko daga 4 + 3.
• Gabaɗaya, wani yana da ƙimar Gleason na 7 wanda ya fito daga ƙara 3 + 4 ana jin yana da ƙananan ciwon daji fiye da wanda yake da Gleason ci 7 wanda ya zo daga ƙara 4 + 3. Wannan saboda mutumin da yake da 4 + 3 = Kashi 7 yana da kwayoyi masu daraja 4 fiye da kwayoyi 3. Kwayoyin 4 na aji sunfi zama marasa kyau kuma sunfi saurin yadawa fiye da kwaya 3.

An ƙirƙiri sabon Groupungiyar Rukunin Grade 5 kwanan nan Wannan tsarin shine mafi kyawun hanyar kwatanta yadda ciwon daji zaiyi aiki da amsa ga magani.

• Groupungiyar 1 ta Grade: Gleason ya ci 6 ko ƙasa (ƙananan ciwon daji)
• Groupungiyar 2 ta Grade: Gleason ya ci 3 + 4 = 7 (matsakaicin matsakaicin ciwon daji)
• Groupungiyar 3 na Grade: Gleason ya ci 4 + 3 = 7 (matsakaicin matsakaicin ciwon daji)
• Groupungiyar 4 ta Grade: Sakamakon Gleason 8 (babban ciwon daji)
• Groupungiyar 5 ta Grade: Gleason ya ci 9 zuwa 10 (babban ciwon kansa)

Groupananan rukuni na nuna kyakkyawar dama don maganin nasara fiye da rukuni mafi girma. Wani rukuni mafi girma yana nufin cewa yawancin ƙwayoyin cutar kansa sun bambanta da ƙwayoyin al'ada. Wani rukuni mafi girma kuma yana nufin cewa akwai yiwuwar ƙari zai iya bazuwa sosai.

Matsayi yana taimaka maka da likitanka don ƙayyade zaɓuɓɓukan maganin ku, tare da:

• Matakin kansar, wanda ke nuna yadda cutar ta yadu sosai
• Sakamakon gwajin PSA
• Lafiyar ku gaba daya
• Bukatar ku don yin tiyata, radiation, ko magungunan hormone, ko babu magani kwata-kwata

Ciwon kanji - Gleason; Adenocarcinoma prostate - Gleason; Darajan Gleason; Gleason ci; Kungiyar Gleason; Ciwon kanjamau - rukuni na 5

Bostwick DG, Cheng L. Neoplasms na prostate. A cikin: Cheng L, MacLennan GT, Bostwick DG, eds. Urologic Mutuwar Hoto. 4th ed. Philadelphia, PA: Elsevier; 2020: babi na 9.

Epstein JI. Pathology na cutar neoplasia. A cikin: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; 2021: babi na 151.

Yanar gizo Cibiyar Cancer ta Kasa. Maganin ciwon daji na ƙwayar cuta (PDQ) - fasalin ƙwararrun masu kiwon lafiya. www.cancer.gov/types/prostate/hp/prostate-treatment-pdq#_2097_toc. An sabunta Yuli 22, 2020. An shiga Agusta 10, 2020.

• Prostate Cancer