Lopinavir da Ritonavir

Wadatacce

• Kafin shan lopinavir da ritonavir,
• Lopinavir da ritonavir na iya haifar da illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:
• Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun bayyanar, kira likitan ku nan da nan ko ku sami magani na gaggawa:

Lopinavir da ritonavir a halin yanzu ana nazarin su a cikin karatun asibiti da yawa da ke gudana don maganin cutar coronavirus 2019 (COVID-19) ko dai shi kaɗai ko tare da wasu magunguna. Amfani da lopinavir da ritonavir don kula da COVID-19 har yanzu ba a kafa shi ba. Wasu masana kimiyya suna da bege saboda an yi amfani da waɗannan magungunan don magance irin wannan cututtukan ƙwayoyin cuta.

Lopinavir da ritonavir yakamata a ɗauka a ƙarƙashin jagorancin likita don maganin COVID-19.

Ana amfani da haɗin lopinavir da ritonavir tare da wasu magunguna don magance ƙwayar ƙwayar ƙwayar ƙwayar ɗan adam (HIV). Lopinavir da ritonavir suna cikin ajin magunguna wadanda ake kira masu hana yaduwar cutar. Suna aiki ne ta hanyar rage yawan kwayar cutar HIV a cikin jini. Lokacin da ake ɗaukar lopinavir da ritonavir tare, ritonavir shima yana taimakawa wajen ƙara yawan lopinavir a cikin jiki ta yadda maganin zai yi tasiri sosai. Kodayake lopinavir da ritonavir ba za su warkar da kwayar cutar HIV ba, waɗannan magunguna na iya rage damarku na haɓaka cututtukan rashin ƙarancin cuta (AIDS) da cututtukan da ke da alaƙa da HIV kamar haɗari mai tsanani ko kansa. Shan waɗannan magunguna tare da yin amintaccen jima'i da yin wasu canje-canje na rayuwa na iya rage haɗarin watsa kwayar cutar HIV zuwa wasu mutane.

Haɗuwa da lopinavir da ritonavir sun zo azaman kwamfutar hannu da mafita (ruwa) don ɗauka ta baki. Yawanci ana shan shi sau biyu a rana, amma wasu manya zasu iya shan sau ɗaya a rana. Dole ne a sha maganin tare da abinci. Ana iya ɗaukar allunan tare da ko ba abinci. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Loauki lopinavir da ritonavir daidai yadda aka umurta. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Hada hadiyar allunan duka; kada ku rarraba, ku tauna, ko murkushe su.

Idan kuna amfani da maganin, girgiza shi sosai kafin kowane amfani don haɗa magungunan daidai. Yi amfani da cokali mai auna ma'auni ko ƙoƙo don auna adadin ruwa daidai gwargwado, ba cokali na gida na yau da kullun ba.

Ci gaba da ɗaukar lopinavir da ritonavir koda kuna jin daɗi. Kada ka daina shan lopinavir da ritonavir ba tare da ka yi magana da likitanka ba. Idan ka rasa allurai, ɗauki ƙasa da adadin da aka ƙayyade, ko dakatar da shan lopinavir da ritonavir, yanayinka na iya zama da wahalar magani.

Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan lopinavir da ritonavir,

• gaya ma likitan ka da likitan ka idan kana rashin lafiyan lopinavir, ritonavir (Norvir), ko wasu magunguna, ko kuma wani sinadarai a cikin lopinavir da ritonavir Allunan ko kuma maganin su. Tambayi likitan ku kan jerin kayan hadin.
• gaya wa likitanka idan kuna shan ɗayan magunguna masu zuwa: alfuzosin (Uroxatral); apalutamide (Erleada); cisapride (Propulsid) (babu a Amurka); colchicine (Colcrys, Mitigare) a cikin mutanen da ke da cutar koda ko hanta; dronedarone (Multaq); elbasvir da grazoprevir (Zepatier); ergot magunguna kamar dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, a Cafergot, a Migergot), da methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Altoprev); lurasidone (Latuda); midazolam da aka sha ta baki (Aya); pimozide (Orap); ranolazine (Ranexa); rifampin (Rimactane, Rifadin, a cikin Rifamate, a cikin Rifater); sildenafil (kawai alamar Revatio da ake amfani da ita don cutar huhu); simvastatin (Zocor, a cikin Vytorin); St. John’s wort; ko triazolam (Halcion). Kila likitanku zai gaya muku kar ku ɗauki lopinavir da ritonavir idan kuna shan ɗaya ko fiye daga waɗannan magunguna.
• gaya wa likitan ku da likitan kantin ku wasu irin takaddun magani da magunguna marasa magani, bitamin, da kayan abinci mai gina jiki da kuke sha. Tabbatar da ambaci wani daga cikin masu zuwa: masu hana yaduwar jini (‘masu kara jini)’ kamar warfarin (Coumadin, Jantoven) da rivaroxaban (Xarelto); antifungals kamar su itraconazole (Onmel, Sporanox), isavuconazonium (Cresemba), ketoconazole (Nizoral), da voriconazole (Vfend); atovaquone (Mepron, a cikin Malarone); bedaquiline (Sirturo); masu hana beta; bosentan (Tracleer); bupropion (Wellbutrin, Zyban, wasu); masu toshe hanyar amfani da alli kamar su felodipine, nicardipine (Cardene), da nifedipine (Adalat, Afeditab CR, Procardia); magungunan cholesterol kamar su atorvastatin (Lipitor, in Caduet), da rosuvastatin (Crestor); clarithromycin (Biaxin, a cikin Prevpac); digoxin (Lanoxin); elagolix (Orilissa); fentanyl (Actiq, Duragesic, Onsolis, wasu); fosamprenavir (Lexiva); wasu magunguna don cutar kansa kamar abemaciclib (Verzenio), dasatinib (Sprycel), karfafarafenib (Braftovi), ibrutinib (Imbruvica), ivosidenib (Tibsovo), neratinib (Nerlynx), nilotinib (Tasigna), venetoclax (Venclexine), ; wasu magunguna don bugun zuciya mara kyau kamar amiodarone (Cordarone, Nexterone, Pacerone), bepridil (babu su a Amurka; Vascor), lidocaine (Lidoderm; a Xylocaine tare da Epinephrine), da quinidine (a Nuedexta); wasu magunguna don cutar hepatitis C virus (HCV) kamar su boceprevir (Victrelis; yanzu ba a Amurka); glecaprevir da pibrentasvir (Mavyret); simeprevir (ba a samun shi a cikin Amurka; Olysio); sofosbuvir, velpatasvir, da voxilaprevir (Sovaldi, Epclusa, Vosevi); da paritaprevir, ritonavir, ombitasvir, da / ko dasabuvir (Viekira Pak); wasu magunguna don kamuwa kamar carbamazepine (Equetro, Tegretol, Teril, wasu), lamotrigine (Lamictal), phenobarbital, phenytoin (Dilantin, Phenytek), da valproate; magunguna da ke murƙushe garkuwar jiki kamar cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), da tacrolimus (Astagraf, Prograf); methadone (Dolophine, Methadose); maganin baki ko inha kamar betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, in Advair), methylprednisolone (Medrol), mometasone (a Dulera). prednisone (Rayos), da kuma triamcinolone; wasu magungunan rigakafi irin su abacavir (Ziagen, a cikin Epzicom, a Trizivir, wasu); atazanavir (Reyataz, a cikin Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, a Atripla), indinavir (Crixivan), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norv) (Viread, a Atripla, a cikin Truvada), tipranavir (Aptivus), saquinavir (Invirase), da zidovudine (Retrovir, a Combivir, a Trizivir); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, a cikin Advair); sildenafil (Viagra); tadalafil (Adcirca, Cialis); trazodone; da vardenafil (Levitra). Idan kana shan maganin na baka, ka gaya ma likitanka idan kana shan disulfiram (Antabuse) ko metronidazole (Flagyl, a Nuvessa, a Vandazole). Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa.
• idan kuna shan didanosine, ɗauki sa'a 1 kafin ko awa 2 bayan kun ɗauki maganin lopinavir da ritonavir tare da abinci. Idan kana shan lopinavir da ritonavir Allunan, zaka iya ɗaukarsu a cikin woshi a dai dai lokacin da kake shan didanosine.
• gaya wa likitanka idan kana da ko ka taɓa yin tazarar tazarar ta QT (wata matsala ta zuciya wacce ba zata iya haifar da bugun zuciya ba, sumewa, ko kuma mutuwa ba zato ba tsammani), bugun zuciya ba daidai ba, ƙarancin sinadarin potassium a cikin jininka, hemophilia, high cholesterol ko triglycerides (mai) a cikin jini, pancreatitis (kumburin pancreas), ko zuciya ko cutar hanta.
• ya kamata ku sani cewa lopinavir da ritonavir na iya rage tasirin maganin hana daukar ciki na ciki (kwayoyin hana haihuwa, faci, zobe, ko allura). Yi magana da likitanka game da amfani da wani nau'i na hana haihuwa.
• gaya wa likitanka idan kana da juna biyu, shirya yin ciki, ko kuma shayarwa. Idan kun yi ciki yayin shan lopinavir da ritonavir, kira likitan ku. Bai kamata ku shayar da nono ba idan kun kamu da kwayar cutar HIV ko kuma idan kuna shan lopinavir da ritonavir.
• Ya kamata ku sani cewa wasu abubuwan sinadarai a cikin lopinavir da maganin ritonavir na iya haifar da mummunan sakamako mai barazanar rai ga jarirai sabbin haihuwa. Ba za a ba Lopinavir da maganin na ritonavir ga cikakkun yara masu ƙarancin shekaru 14 ba ko kuma ga yara ƙanana da ba su wuce kwanaki 14 ba da ranar haihuwar su ta asali, sai dai in likita yana ganin akwai kyakkyawan dalili don jaririn ya karɓi magunguna daidai bayan haihuwa. Idan likitan jaririn ya zaɓi ya ba wa jaririn lopinavir da ritonavir bayani nan da nan bayan haihuwa, za a kula da jaririn a hankali don alamun alamun sakamako masu illa. Kira likitan jaririn ku nan da nan idan jaririn ku mai matukar barci ne ko kuma yana da canje-canje a numfashi yayin jinyarsa tare da maganin lopinavir da na al'ada na ritonavir
• ya kamata ku sani cewa kitsen jikinku na iya karuwa ko motsawa zuwa wurare daban-daban na jikinku, kamar su na baya, wuyan ku ('' buffalo hump ''), nono, da kewaye da cikin ku. Kuna iya lura da asarar kitsen jiki daga fuskarka, ƙafafunku, da hannayenku.
• ya kamata ku sani cewa kuna iya fuskantar hyperglycemia (ƙaruwa a cikin jinin ku) yayin shan wannan magani, koda kuwa baku da ciwon suga. Faɗa wa likitanka kai tsaye idan kana da ɗayan waɗannan alamun yayin da kake shan lopinavir da ritonavir: ƙishirwa mai yawa, yawan fitsari, yunwa mai tsanani, hangen nesa, ko rauni. Yana da matukar muhimmanci ka kira likitanka da zaran ka samu irin wadannan alamun, saboda yawan hawan jini da ba a kula da shi na iya haifar da mummunan yanayi da ake kira ketoacidosis. Ketoacidosis na iya zama barazanar rai idan ba a bi da shi a farkon matakin ba. Kwayar cutar ketoacidosis sun hada da: bushewar baki, tashin zuciya da amai, yawan numfashi, numfashin da ke warin 'ya'yan itace, da rage hankali.
• Ya kamata ka sani cewa yayin da kake shan magunguna don magance cutar kanjamau, garkuwar jikinka zata ƙara ƙarfi ta fara yaƙi da wasu cututtukan da suke jikinka. Wannan na iya haifar da ci gaba da bayyanar cututtukan. Idan kana da sababbi ko munanan cututtuka bayan fara magani tare da lopinavir da ritonavir, ka tabbata ka gayawa likitanka.

Sai dai idan likitanku ya gaya muku in ba haka ba, ci gaba da abincinku na yau da kullun.

Doseauki kashi da aka rasa da zarar kun tuna shi. Koyaya, idan ya kusan zuwa lokaci na gaba, tsallake kashi da aka rasa kuma ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Lopinavir da ritonavir na iya haifar da illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:

• rauni
• gudawa
• gas
• ƙwannafi
• asarar nauyi
• ciwon kai
• wahalar bacci ko bacci
• ciwon tsoka
• suma, ƙonewa, ko ƙwanƙwasawa a hannu ko ƙafa
• ciwon ciki, jiri, da amai

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun bayyanar, kira likitan ku nan da nan ko ku sami magani na gaggawa:

• tashin zuciya
• amai
• ciwon ciki
• matsanancin gajiya
• rasa ci
• zafi a cikin ɓangaren dama na ciki
• rawaya fata ko idanu
• fata mai ƙaiƙayi
• jiri
• rashin haske
• suma
• bugun zuciya mara tsari
• kumfa
• kurji

Lopinavir da ritonavir na iya haifar da wasu sakamako masu illa. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.

Idan kun fuskanci mummunan sakamako, ku ko likitanku na iya aika rahoto ga shirin Abinci da Magunguna na Hukumar Kula da Abinci da Magunguna (FDA) na kan layi (http://www.fda.gov/Safety/MedWatch) ko ta waya ( 1-800-332-1088).

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye allunan a zafin jiki na daki kuma kare su daga yawan danshi. Zai fi kyau a ajiye allunan a cikin akwatin da suka shigo; idan dole ne ka dauke su daga cikin akwatin, yakamata kayi amfani dasu cikin sati 2. Kuna iya adana maganin na baka a cikin firiji har zuwa ranar karewa da aka buga akan tambarin, ko kuma kuna iya ajiye shi a cikin zafin jiki na daki na tsawon watanni 2.

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani.Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Idan ya wuce gona da iri, kira layin taimakon guba a 1-800-222-1222. Hakanan ana samun bayanai akan layi akan https://www.poisonhelp.org/help. Idan wanda aka azabtar ya faɗi, ya kamu, fama da numfashi, ko ba za a iya farkawa ba, nan da nan kira sabis na gaggawa a 911.

Yana da mahimmanci musamman don samun taimakon likita yanzunnan idan yaro ya sha fiye da yadda aka saba sha. Maganin ya ƙunshi adadi mai yawa na giya da sauran abubuwan haɗari waɗanda zasu iya cutar da yaro sosai.

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanku zai ba da umarnin wasu gwaje-gwajen gwaje-gwaje don bincika amsar jikinku ga lopinavir da ritonavir.

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

• Kaletra^® (dauke da Lopinavir, Ritonavir)