Methionine: Ayyuka, Tushen Abinci da Tasirin Gefen

Wadatacce

• Menene Methionine?
• Zai Iya samar da ƙwayoyin cuta Mahimmanci don Ayyukan Kwayar Al'ada
• Yana taka rawa a cikin Methylation DNA
• Abincin Abincin Methionine Mai Extara Tsawo Na Rayuwa a Dabbobi
• Tushen abinci na Methionine
• Sha, Abincin da kuma Illolin da yake haifarwa
• Nagari Amfani
• Tasiri kan Homocysteine
• Tasirin Gefen
• Layin .asa

Amino acid suna taimakawa wajen gina sunadarai wadanda suka hada da kyallen takarda da gabobin jikin ku.

Baya ga wannan muhimmin aiki, wasu amino acid suna da wasu matsayi na musamman.

Methionine amino acid ne wanda ke samar da mahimman kwayoyin halitta a jikin ku. Waɗannan ƙwayoyin suna da mahimmanci don dacewar ƙwayoyinku.

Saboda mahimman kwayoyin da yake samarwa, wasu suna ba da shawarar ƙara yawan abincin methionine. Koyaya, wasu suna ba da shawarar iyakance shi saboda yiwuwar illa mara kyau.

Wannan labarin zai tattauna mahimmancin methionine kuma ko kuna buƙatar damuwa game da adadin shi a cikin abincinku. Hakanan ana tattauna tushen tushe da kuma illolin dake tattare dashi.

Menene Methionine?

Methionine amino acid ne wanda ake samu a cikin sunadarai da yawa, gami da sunadaran dake cikin abinci da wadanda ake samu a kyallen takarda da gabobin jikin ku.

Baya ga kasancewa tubalin gini don sunadarai, yana da wasu fasali na musamman da yawa.

Ofayan waɗannan shine ikon sa a canza shi zuwa mahimman ƙwayoyin sunadarin sulfur ().

Kwayoyin sunadarin Sulfur suna da ayyuka iri-iri, gami da kariyar ƙwayoyinku, gyaran DNA ɗinka da kiyaye aikin kwayarku da kyau (, 3).

Dole a samar da wadannan muhimman kwayoyin daga amino acid wadanda suke dauke da sinadarin sulphur. Daga cikin amino acid da ake amfani dasu don samar da sunadarai a jiki, methionine da cysteine ​​ne kawai ke dauke da sinadarin sulphur.

Kodayake jikinku na iya samar da amino acid cysteine ​​da kansa, methionine dole ne ya fito daga abincinku (4).

Bugu da ƙari, methionine yana taka muhimmiyar rawa wajen fara aiwatar da sabbin furotin a cikin ƙwayoyinku, wani abu da ke ci gaba da faruwa yayin da tsofaffin sunadarai ke lalacewa ().

Misali, wannan amino acid din yana fara aiwatarda sabbin sunadarai ne a cikin jijiyoyinka bayan wani zaman motsa jiki da yake lalata su (,).

Methionine amino acid ne na musamman. Ya ƙunshi sulphur kuma yana iya samar da wasu ƙwayoyi masu ƙunzir da ke cikin jiki. Hakanan yana da hannu wajen fara samar da furotin a cikin kwayoyin jikin ku.

Zai Iya samar da ƙwayoyin cuta Mahimmanci don Ayyukan Kwayar Al'ada

Ofayan mahimmancin aikin methionine a cikin jiki shine cewa ana iya amfani dashi don samar da wasu mahimman kwayoyin.

Yana da hannu wajen samar da sinadarin cysteine, sauran amino acid din da ke dauke da guba wanda ake amfani da shi wajen gina sunadarai a jiki (,).

Cysteine ​​na iya, bi da bi, ƙirƙirar nau'ikan kwayoyin, gami da sunadarai, glutathione da taurine ().

Glutathione wani lokaci ana kiransa “master antioxidant” saboda mahimmiyar rawar da yake takawa a kare garkuwar jikinka (,).

Hakanan yana taka rawa wajen samarda abinci mai gina jiki a jiki da samar da DNA da sunadarai ().

Taurine yana da ayyuka da yawa waɗanda ke taimakawa kula da lafiya da ingantaccen aiki na ƙwayoyin ku ().

Daya daga cikin mahimman kwayoyin methionine da za'a iya jujjuya su shine S-adenosylmethionine, ko "SAM" ().

SAM yana shiga cikin halayen sunadarai daban-daban ta hanyar canza sashin kansa zuwa wasu kwayoyin, gami da DNA da sunadarai (3,).

Ana amfani da SAM a cikin samar da halitta, muhimmin kwaya don kuzarin salula (,).

Gabaɗaya, methionine yana da hannu kai tsaye ko kai tsaye a cikin mahimman matakai masu yawa a cikin jiki saboda ƙwayoyin da zai iya zama.

Methionine na iya canzawa zuwa cikin ƙwayoyin da ke dauke da sulfur tare da mahimman ayyuka, kamar su glutathione, taurine, SAM da creatine. Wadannan kwayoyin suna da mahimmanci ga aikin al'ada na sel a jikinka.

Yana taka rawa a cikin Methylation DNA

DNA dinka ya kunshi bayanan da zasu baka damar zama kai.

Duk da yake yawancin wannan bayanin na iya kasancewa ɗaya ne a rayuwar ku duka, abubuwan da ke cikin muhalli na iya canza wasu abubuwan DNA ɗin ku.

Wannan shine ɗayan mafi ban sha'awa matsayin na methionine - cewa zai iya canzawa zuwa kwayar halitta da ake kira SAM. SAM na iya canza DNA ɗinka ta hanyar ƙara methyl group (carbon atom da mahaɗan hydrogen da ke haɗe da ita) (3,).

Adadin methionine a cikin abincinku na iya shafar yawancin wannan aikin da ke faruwa, amma akwai tambayoyi da yawa da ba a amsa ba game da wannan.

Yana yiwuwa kara methionine a cikin abincin zai iya haɓaka ko rage yadda DNA ɗinku ya canza sakamakon SAM ().

Bugu da ƙari, idan waɗannan canje-canje suka faru, za su iya zama fa'ida a wasu lokuta amma cutarwa a cikin wasu ().

Misali, wasu bincike sun nuna cewa abinci mafi girma a cikin abubuwan gina jiki wadanda suka hada kungiyoyin methyl zuwa DNA dinka na iya rage hadarin kamuwa da cutar kansa ().

Koyaya, sauran bincike sun nuna cewa yawan shan methionine na iya kara dagula yanayi kamar schizophrenia, wataƙila saboda ƙara ƙarin ƙungiyoyin methyl zuwa DNA (,).

Daya daga cikin kwayoyin da methionine ya samar, SAM, na iya canza maka DNA. Ba a bayyana cikakke yadda abubuwan methionine na abincinku ke shafar wannan aikin ba, kuma yana yiwuwa wannan tsari yana da alfanu a wasu lokuta kuma yana da lahani a wasu.

Abincin Abincin Methionine Mai Extara Tsawo Na Rayuwa a Dabbobi

Kodayake methionine yana da mahimmin matsayi a cikin jiki, wasu bincike suna nuna fa'idodin abincin da basu da yawa a cikin wannan amino acid.

Wasu ƙwayoyin daji suna dogara ga methionine na abinci don yayi girma. A cikin waɗannan sharuɗɗan, iyakance cin abincinku na iya zama da fa'ida don taimakawa ƙwayoyin cutar kansa ().

Tun da sunadarai daga tsire-tsire galibi suna ƙasa da methionine fiye da furotin na dabbobi, wasu masu bincike sunyi imanin cewa abincin da ake shukawa na iya zama kayan aiki don yaƙi da wasu cututtukan daji (,).

Bugu da ƙari, nazarin da yawa a cikin dabbobi ya nuna cewa rage methionine na iya ƙara tsawon rai da inganta lafiya (,,).

Studyaya daga cikin binciken ya gano cewa tsawon rai ya wuce 40% a cikin beraye suna ciyar da ƙananan abincin methionine ().

Wannan tsawon rai na iya kasancewa ne saboda ingantaccen juriya da narkewar jiki tare da kiyaye karfin kwayayen jiki na haifuwa (,).

Wasu masu binciken sun yanke hukuncin cewa karancin sinadarin methionine yana yin aiki ne don rage saurin tsufa a cikin beraye ().

Ko waɗannan fa'idodin sun faɗo ga mutane ba a bayyane yake ba tukuna, amma wasu binciken-tube tube sun nuna fa'idodi na ƙananan kayan methionine a cikin ƙwayoyin mutum (,).

Koyaya, ana buƙatar binciken ɗan adam kafin a yanke shawara.

A cikin dabbobi, rage abubuwan dake cikin methionine na abinci na iya rage saurin tsufa da kuma kara tsawon rai. Wasu nazarin sun nuna fa'idodin rage methionine a cikin ƙwayoyin mutum, amma ana buƙatar bincike a cikin mutane masu rai.

Tushen abinci na Methionine

Duk da yake kusan dukkanin abincin da ke dauke da sunadarai suna da methionine, adadin ya bambanta sosai. Qwai, kifi da wasu nama suna dauke da adadi mai yawa na wannan amino acid (23).

An kiyasta cewa kusan 8% na amino acid a cikin kwai fata sune amino acid (methionine da cysteine) masu dauke da sulphur ().

Wannan darajar ta kusan 5% a cikin kaza da naman sa da kuma kashi 4% a cikin kayan kiwo. Sunadaran gina jiki galibi suna da ƙananan amino acid din.

Wasu bincike sun kuma bincika yawan adadin amino acid mai dauke da sulfur (methionine da cysteine) a cikin nau'ikan abincin ().

An bayar da rahoton mafi girman abun ciki (gram 6.8 a kowace rana) a cikin abinci mai gina jiki, yayin da ƙananan cin abinci ke kasancewa ga masu cin ganyayyaki (gram 3.0 a kowace rana) da kuma masu cin ganyayyaki (gram 2.3 kowace rana).

Duk da karancin cin abinci a tsakanin masu cin ganyayyaki, sauran bincike sun nuna cewa a zahiri suna da tarin jini na methionine fiye da waɗanda suke cin nama da kifi ().

Wannan binciken ya sa masu binciken suka yanke shawarar cewa abun cikin abinci da yawan jini na methionine ba koyaushe suke da alaƙa kai tsaye ba.

Koyaya, waɗannan karatun sun gano cewa masu cin ganyayyaki suna da ƙarancin abincin abinci da ƙarancin jini na methionine (,).

Sunadaran dabba galibi suna da babban abun cikin methionine fiye da sunadaran shuka. Wadanda ke bin tsarin abinci na tsirrai suna da karancin abincin amino acid masu dauke da sulfur, kodayake suna iya samun ko dai mafi girma ko ƙananan matakan methionine a cikin jini.

Sha, Abincin da kuma Illolin da yake haifarwa

Masu bincike sun kafa shawarar cin amino acid mai dauke da sulfur (methionine da cysteine) a kullum, amma kuma nazarin ya binciko illolin da ke tattare da hakan.

Nagari Amfani

Ana amfani da shawarar yau da kullun na methionine tare da cysteine ​​8.6 mg / lb (19 mg / kg) kowace rana don manya, wanda yake kusan gram 1.3 ga wanda yakai fam 150 (kilogram 68) (4).

Koyaya, wasu masu binciken sun ba da shawarar cinye ninki biyu wannan gwargwadon iyakokin karatun da aka yi amfani da su don saita shawarar da aka ba da shawarar ().

Tsofaffi galibi suna da ƙarancin abincin methionine, kuma karatu ya nuna cewa suna iya buƙatar haɓakar 2 zuwa 3 gram mafi girma kowace rana (,).

Duk da cewa wasu kungiyoyi zasu iya amfanuwa da kara yawan sinadarin na methionine, yawancin abincin sun wuce gram 2 a kowace rana na sinadarin methionine da kuma maganin cysteine.

An kiyasta nau'o'in abinci iri-iri, gami da ganyayyaki, ganyayyaki, na gargajiya da na furotin mai yawa tsakanin gram 2.3 zuwa 6.8 a kowace rana na waɗannan amino acid ().

Tasiri kan Homocysteine

Wataƙila mafi girman damuwa da ke haɗuwa da haɓakar methionine mai yawa shine saboda ɗayan ƙwayoyin wannan amino acid ɗin zai iya samarwa.

Methionine na iya canzawa zuwa homocysteine, amino acid da ke da alaƙa da ɓangarori da yawa na cututtukan zuciya (,).

Babban haɗarin methionine na iya haifar da ƙaruwa a cikin homocysteine, kodayake wasu mutane sun fi saukin wannan aikin fiye da wasu ().

Abin sha'awa, bincike yana nuna cewa haɗarin haɗarin yawan shan methionine na iya zama saboda homocysteine ​​maimakon methionine kanta ().

Koyaya, akwai wasu abubuwan da zasu iya canza matakan homocysteine.

Misali, kodayake suna da karancin abincin methionine, masu cin ganyayyaki da masu cin ganyayyaki na iya samun homocysteine ​​mafi girma fiye da komai saboda ƙarancin bitamin B12 ().

Sauran bincike sun nuna babban furotin, abinci mai sinadarin methionine bai kara yawan homocysteine ​​ba bayan watanni shida, idan aka kwatanta shi da furotin mai gina jiki, mai rage methionine ().

Bugu da ƙari, canza canjin abinci har zuwa 100% bai bayyana yana shafar homocysteine ​​a cikin manya masu lafiya ba tare da raunin bitamin ba ().

Tasirin Gefen

Don kimanta martani na jiki ga methionine, masu bincike zasu ba da kashi ɗaya na wannan amino acid kuma su lura da sakamakon.

Wannan kashi ya fi girma fiye da shawarar da aka ba da shawara, sau da yawa kusan 45 mg / lb (100 mg / kg), ko gram 6.8 ga wanda yayi nauyin kilogram 150 (kilogram 68) ().

An yi wannan nau'in gwajin a kan lokutan 6,000, tare da ƙananan ƙananan sakamako masu illa. Wadannan kananan illolin sun hada da jiri, bacci da canjin hawan jini ().

Majoraya daga cikin manyan abubuwan da suka faru sun faru yayin ɗayan waɗannan gwaje-gwajen, wanda ya haifar da mutuwar mutum mai cutar hawan jini amma yana da ƙoshin lafiya in ba haka ba ().

Koyaya, da alama yawan haɗarin haɗari na kusan sau 70 yawan abincin da aka ba da shawarar ya haifar da rikitarwa ().

Gabaɗaya, ya bayyana cewa methionine ba mai cutarwa ba ne musamman a cikin mutane masu ƙoshin lafiya, sai dai a ƙananan allurai waɗanda kusan ba zai yiwu a samu ta hanyar abincin ba.

Kodayake methionine yana da hannu wajen samar da homocysteine, amma babu wata hujja da ke nuna cewa cin abinci a cikin wani yanayi na da hadari ga lafiyar zuciya ().

Mutanen da ke bin nau'o'in abinci da yawa sau da yawa za su wuce mafi ƙarancin shawarar methionine. Sakamakon sakamako don mayar da martani ga manyan allurai galibi ƙananan amma zai iya zama haɗari a maɗaukakiyar allurai.

Layin .asa

Methionine shine amino acid mai dauke da sulfur na musamman wanda za'a iya amfani dashi don gina sunadarai da samar da ƙwayoyi da yawa a jiki.

Wadannan sun hada da antioxidant glutathione da molecule SAM, wanda ake amfani dashi don gyara DNA da sauran kwayoyin.

Ana samun Methionine a cikin nau'ikan abinci masu dauke da sunadarai kuma galibi ya fi sunadaran dabba girma fiye da sunadaran shuka. Kodayake an nuna abincin mai ƙananan methionine don tsawanta rayuwa a cikin dabbobi, ko wannan yana da mahimmanci ga ɗan adam bai bayyana ba tukuna.

Mutanen da ke cin nau'ikan abinci iri daban-daban galibi suna haɗuwa da shawarar methionine, kodayake wasu tsofaffi na iya amfanuwa da ƙara yawan abincinsu.

Sakamakon sakamako don mayar da martani ga manyan allurai yawanci ƙananan amma zai iya zama mai haɗari a ƙananan allurai fiye da abin da za'a iya samu ta hanyar abincin yau da kullun.

Dangane da binciken da aka samo a cikin mutane masu ƙoshin lafiya, mai yiwuwa baku buƙatar iyakance ko ƙara yawan abincin methionine a cikin abincinku ba.