Gwajin Pharmacogenetic
Wadatacce
- Menene gwajin magani?
- Me ake amfani da shi?
- Me yasa nake buƙatar gwajin magunguna?
- Menene ya faru yayin gwajin magani?
- Shin zan bukaci yin komai don shirya wa gwajin?
- Shin akwai haɗari ga gwajin?
- Menene sakamakon yake nufi?
- Shin akwai wani abin da nake buƙatar sani game da gwajin magunguna?
- Bayani
Menene gwajin magani?
Pharmacogenetics, wanda ake kira pharmacogenomics, shi ne nazarin yadda kwayoyin halitta ke shafar amsar jiki ga wasu magunguna. Kwayar halitta sassan DNA ne da aka ratsa daga uwa da uba. Suna ɗauke da bayanan da ke tantance halaye na musamman, kamar su tsayi da launin ido. Hakanan kwayoyin halittar ku na iya shafar yadda aminci da tasirin wani magani na musamman zai iya zama muku.
Kwayoyin halitta na iya zama dalilin irin magani iri daya zai shafi mutane ta hanyoyi daban daban. Kwayar halitta na iya zama dalilin da yasa wasu mutane ke da mummunar illa ga magani, yayin da wasu basu da komai.
Gwajin Pharmacogenetic yana kallon takamaiman kwayoyin halitta don taimakawa gano nau'in magunguna da ƙwayoyi waɗanda zasu iya zama daidai a gare ku.
Sauran sunaye: magunguna, gwajin magani
Me ake amfani da shi?
Ana iya amfani da gwajin Pharmacogenetic don:
- Gano ko wani magani zai iya yi muku tasiri
- Gano abin da mafi kyawun sashi zai iya zama muku
- Yi annabta ko za ku sami mummunan sakamako daga magani
Me yasa nake buƙatar gwajin magunguna?
Mai ba ku kiwon lafiya na iya yin odar waɗannan gwaje-gwajen kafin fara wani magani, ko kuma idan kuna shan magani wanda ba ya aiki kuma / ko haifar da mummunan sakamako.
Ana samun gwajin Pharmacogenetic ne kawai don iyakance adadin magunguna. A ƙasa akwai wasu magunguna da ƙwayoyin halitta waɗanda za a iya gwada su. (Ana ba da sunayen mutane yawanci a cikin haruffa da lambobi.)
Magani | Kwayoyin halitta |
---|---|
Warfarin: mai kara jini | CYP2C9 da VKORC1 |
Plavix, mai sirantar jini | BAB2C19 |
Magungunan rage damuwa, magungunan farfadiya | CYP2D6, CYPD6 CYP2C9, CYP1A2, SLC6A4, HTR2A / C |
Tamoxifen, maganin kansar nono | CYPD6 |
Antipsychotics | DRD3, CYP2D6, CYP2C19, CYP1A2 |
Jiyya don matsalar raunin hankali | D4D4 |
Carbamazepine, magani don farfadiya | HLA-B * 1502 |
Abacavir, maganin cutar kanjamau | HLA-B * 5701 |
Opioids | 1 |
Statins, magungunan da ke magance babban ƙwayar cholesterol | SLCO1B1 |
Jiyya don cutar sankarar bargo ta yara da wasu cututtukan autoimmune | TMPT |
Menene ya faru yayin gwajin magani?
Ana yin gwaji yawanci akan jini ko yau.
Don gwajin jini, wani kwararren mai kula da lafiya zai dauki samfurin jini daga jijiyar hannunka, ta amfani da karamin allura. Bayan an saka allurar, za a tara karamin jini a cikin bututun gwaji ko kwalba. Kuna iya jin ɗan kaɗan lokacin da allurar ta shiga ko fita. Wannan yawanci yakan dauki kasa da minti biyar.
Don gwajin yau, Tambayi mai kula da lafiyar ku umarni kan yadda zaku bada samfurin ku.
Shin zan bukaci yin komai don shirya wa gwajin?
Yawanci baku buƙatar kowane shiri na musamman don gwajin jini. Idan kana karbar gwajin yau, to, bai kamata ka ci, ko sha, ko shan taba ba tsawon minti 30 kafin gwajin.
Shin akwai haɗari ga gwajin?
Akwai haɗari kaɗan don yin gwajin jini. Kuna iya samun ɗan ciwo ko rauni a wurin da aka sanya allurar, amma yawancin alamun suna tafi da sauri.
Babu haɗarin yin gwajin yau.
Menene sakamakon yake nufi?
Idan an gwada ku kafin fara magani, gwajin na iya nuna ko wataƙila magani zai yi tasiri kuma / ko kuma idan kuna cikin haɗarin mummunan sakamako. Wasu gwaje-gwajen, kamar na wasu magungunan da ke magance farfadiya da cutar kanjamau, na iya nuna ko kuna cikin haɗarin tasirin illa na rayuwa. Idan haka ne, mai ba ku sabis zai yi ƙoƙarin nemo madadin magani.
Gwaje-gwajen da ke faruwa kafin da yayin da kuke kan jiyya na iya taimaka wa mai ba ku kiwon lafiya gano madaidaicin kashi.
Idan kuna da tambayoyi game da sakamakonku, yi magana da mai ba ku kiwon lafiya.
Learnara koyo game da gwaje-gwajen gwaje-gwaje, jeri na tunani, da fahimtar sakamako.
Shin akwai wani abin da nake buƙatar sani game da gwajin magunguna?
Ana amfani da gwajin Pharmacogenetic ne kawai don gano amsar mutum ga takamaiman magani. Ba abu daya bane da gwajin kwayoyin halitta. Yawancin gwaje-gwajen kwayoyin ana amfani da su don taimakawa wajen gano cututtuka ko haɗarin kamuwa da cuta, gano dangantakar iyali, ko gano wani a cikin binciken laifi.
Bayani
- Hefti E, Blanco J. Rubuta Takaddun Gwajin Pharmacogenomic tare da Lambobin Gudanar da Lissafi na Yanzu (CPT) Lambobin, Nazarin Ayyukan da suka gabata da Yanzu. J AHIMA [Intanet]. 2016 Jan [wanda aka ambata 2018 Jun 1]; 87 (1): 56–9. Akwai daga: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
- Gwaje-gwajen Lab a kan layi [Intanet]. Washington DC: Associationungiyar (asar Amirka don Magungunan Kiwon Lafiya; c2001–2018. Gwajin Pharmacogenetic; [sabunta 2018 Jun 1; wanda aka ambata 2018 Jun 1]; [game da allo 2]. Akwai daga: https://labtestsonline.org/tests/pharmacogenetic-tests
- Gwaje-gwajen Lab a kan layi [Intanet]. Washington DC: Associationungiyar (asar Amirka don Magungunan Kiwon Lafiya; c2001–2018. Duniyar Gwajin Halitta; [sabunta 2017 Nuwamba 6; wanda aka ambata 2018 Jun 1]; [game da allo 2]. Akwai daga: https://labtestsonline.org/articles/genetic-testing?start=4
- Mayo Clinic: Cibiyar Magunguna ta Musamman [Intanet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1998–2018. Gwajin kwayar cuta; [aka ambata 2018 Jun 1]; [game da fuska 3]. Akwai daga: http://mayoresearch.mayo.edu/center-for-individualized-medicine/drug-gene-testing.asp
- Mayo Clinic: Cibiyar Magunguna ta Musamman [Intanet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab gwajin; [aka ambata 2018 Jun 1]; [game da fuska 5]. Akwai daga: http://mayoresearch.mayo.edu/center-for-individualized-medicine/cyp2d6-tamoxifen.asp
- Mayo Clinic: Cibiyar Magunguna ta Musamman [Intanet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1998–2018. HLA-B * 1502 / Carbamazepine Pharmacogenomic Lab gwajin; [aka ambata 2018 Jun 1]; [game da fuska 4]. Akwai daga: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab1502-carbamazephine.asp
- Mayo Clinic: Cibiyar Magunguna ta Musamman [Intanet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1998–2018. HLA-B * 5701 / Abacavir Pharmacogenomic Lab gwajin; [wanda aka ambata 2018 Jun 1]; [game da fuska 4]. Akwai daga: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab5701-abacavir.asp
- Mayo Clinic: Mayo Laboratories Medical [Internet]. Gidauniyar Mayo don Ilimin Likita da Bincike; c1995–2018. ID na Gwaji: PGXFP: Mayar da hankali akan acowararren Magungunan Pharmacogenomics: Misali; [wanda aka ambata 2018 Jun 1]; [game da fuska 3]. Akwai daga: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
- Cibiyar Cancer ta Kasa [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; NCI Dictionary of Cancer Sharuddan: gene; [wanda aka ambata 2018 Jun 1]; [game da fuska 3]. Akwai daga: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
- Zuciyar Kasa, Huhu, da Cibiyar Jini [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; Gwajin jini; [aka ambata 2018 Jun 1]; [game da fuska 3]. Akwai daga: https://www.nhlbi.nih.gov/health-topics/blood-tests
- NIH Cibiyar Nazarin Kimiyyar Kiwon Lafiyar Jama'a [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; Pharmacogenomics; [sabunta 2017 Oct; wanda aka ambata 2018 Jun 1]; [game da fuska 4]. Akwai daga: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
- NIH US National Library of Medicine: Nasihu na Gidajen Gida [Intanet]. Bethesda (MD): Ma'aikatar Kiwon Lafiya ta Amurka da Ayyukan Dan Adam; Menene pharmacogenomics ?; 2018 Mayu 29 [wanda aka ambata 2018 Jun 1]; [game da fuska 4]. Akwai daga: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
- Kiwan lafiya na UF: Kiwon Lafiya na Jami'ar Florida [Intanet]. Jami'ar Florida; c2018. Ta yaya kwayoyin halittar ku ke tasiri kan abin da magunguna suka dace da ku; 2016 Jan 11 [sabunta 2018 Jun 1; wanda aka ambata 2018 Jun 1]; [game da allo 2]. Akwai daga: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are-right-you
- UW Health American Family Children's Hospital [Intanet]. Madison (WI): Jami'ar Wisconsin Asibitoci da Hukumomin Kula da Lafiya; c2018. Kiwan yara: Pharmacogenomics; [aka ambata 2018 Jun 1]; [game da fuska 4]. Akwai daga: https://www.uwhealthkids.org/kidshealth/en/parents/pharmacogenomics.html/
Ba za a yi amfani da bayanan da ke wannan rukunin yanar gizon a madadin madadin ƙwararrun likitocin ko shawara ba. Tuntuɓi mai ba da kiwon lafiya idan kuna da tambayoyi game da lafiyarku.