Farkon biliary cirrhosis

Hanyoyin bile sune bututun da ke motsa bile daga hanta zuwa karamar hanji. Bile abu ne wanda yake taimakawa narkewa. Dukkanin bututun bile tare ana kiransu biliary tract.

Lokacin da bututun bile suka kumbura ko kumbura, wannan yana toshe kwararar bile. Wadannan canje-canjen na iya haifar da tabon hanta da ake kira cirrhosis. Wannan shi ake kira biliary cirrhosis. Ciwon cirrhosis na gaba na iya haifar da gazawar hanta.

Ba a san musabbabin kumburin ciki ba na hanta. Koyaya, cutar biliary cirrhosis cuta ce ta autoimmune. Wannan yana nufin tsarin garkuwar jikinku bisa kuskure ya kai hari ga lafiyayyen nama. Cutar na iya kasancewa da alaƙa da cututtukan ƙwayoyin cuta kamar:

• Celiac cuta
• Raynaud sabon abu
• Ciwon Sicca (bushewar idanu ko baki)
• Ciwon thyroid

Cutar ta fi shafar mata masu matsakaitan shekaru.

Fiye da rabin mutane ba su da alamomi a lokacin ganowar cutar. Kwayar cutar galibi tana farawa ne a hankali. Alamun farko na iya haɗawa da:

• Ciwan ciki da ciwon ciki
• Gajiya da asarar kuzari
• Adadin mai a ƙarƙashin fata
• Kujerun kitso
• Itching
• Rashin cin abinci da rashi nauyi

Yayinda hanta ke kara muni, alamun cutar na iya haɗawa da:

• Ruwan ruwa a cikin kafafu (edema) da kuma cikin ciki (ascites)
• Launi mai launin rawaya a cikin fata, ƙwayoyin mucous, ko idanu (jaundice)
• Redness akan tafin hannu
• A cikin maza, rashin ƙarfin jiki, raguwar ƙwayoyin cuta, da kumburin nono
• Aramar sauƙi da zub da jini mara kyau, galibi galibi daga jijiyoyin kumbura a cikin hanyar narkewar abinci
• Rikicewa ko matsalolin tunani
• Launi mai launi ko mai laushi

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki.

Gwaje-gwaje masu zuwa na iya bincika don ganin idan hanta tana aiki da kyau:

• Gwajin jini na Albumin
• Gwajin aikin hanta (sinadarin alkaline phosphatase yana da mahimmanci)
• Lokacin Prothrombin (PT)
• Cholesterol da gwajin jini na lipoprotein

Sauran gwaje-gwajen da zasu iya taimakawa auna yadda tsananin cutar hanta zai iya haɗuwa da:

• Halin immunoglobulin M wanda yake cikin jini
• Gwajin hanta
• Anti-mitochondrial antibodies (sakamako yana da kyau game da kusan kashi 95% na shari'oi)
• Nau'ikan musamman na duban dan tayi ko MRI waɗanda ke auna adadin tabon nama (ana iya kiransa elastography)
• Magnetic rawa cholangiopancreatography (MRCP)

Manufar magani shine a sauƙaƙe alamomin kuma a hana rikitarwa.

Cholestyramine (ko colestipol) na iya rage itching. Ursodeoxycholic acid na iya inganta cire bile daga cikin jini. Wannan na iya inganta rayuwa a cikin wasu mutane. Akwai kuma wani sabon magani wanda ake kira da obeticholic acid (Ocaliva).

Maganin maye gurbin bitamin yana dawo da bitamin A, K, E da D, waɗanda suka ɓace a cikin kujerun mai. Ana iya saka ƙarin ƙwayar alli ko wasu magungunan ƙashi don hana ko magance rauni ko ƙasusuwa masu laushi.

Ana buƙatar kulawa na dogon lokaci da maganin gazawar hanta.

Yin dashen hanta na iya cin nasara idan aka yi shi kafin hantawar ta gaza.

Sakamakon na iya bambanta. Idan ba a magance yanayin ba, yawancin mutane za su mutu ba tare da dasa hantar ba. Kimanin kashi ɗaya cikin huɗu na mutanen da suka kamu da cutar tsawon shekaru 10 za su kamu da ciwon hanta. Doctors a yanzu za su iya amfani da samfurin ƙididdiga don hango mafi kyawun lokacin da za a yi dasa shi. Sauran cututtuka, kamar hypothyroidism da anemia, suma na iya haɓaka.

Ciwon cirrhosis na ci gaba na iya haifar da gazawar hanta. Matsaloli na iya haɗawa da:

• Zuban jini
• Lalacewa ga kwakwalwa (encephalopathy)
• Rashin ruwa da rashin daidaiton lantarki
• Rashin koda
• Malabsorption
• Rashin abinci mai gina jiki
• Kashi mai laushi ko rauni (osteomalacia ko osteoporosis)
• Ascites (haɓaka ruwa a cikin ramin ciki)
• Riskarin haɗarin ciwon hanta

Kira mai ba ku sabis idan kuna da:

• Ciwan ciki
• Jini a cikin kujerun
• Rikicewa
• Jaundice
• Jin ƙai na fata wanda baya tafiya kuma baya da alaƙa da wasu dalilai
• Jinin amai

Primary biliary cholangitis; PBC

• Cirrhosis - fitarwa

• Tsarin narkewa
• Hanyar Bile

Eaton JE, Lindor KD. Primary biliary cholangitis. A cikin: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger da Cututtukan Cutar hanta da na Fordtran. 11th ed. Philadelphia, PA: Elsevier; 2021: babi na 91.

Fogel EL, Sherman S. Cututtuka na gallbladder da bile ducts. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 146.

Lambobin LW. Hanta: cututtukan da ba na roba ba. A cikin: Goldblum JR, Lamps LW, McKenney JK, Myers JL, eds. Rosai da Ackerman na Ciwon Tiyata. 11th ed. Philadelphia, PA: Elsevier; 2018: babi na 19.

Smith A, Baumgartner K, Bositis C. Cirrhosis: ganewar asali da gudanarwa. Am Fam Likita. 2019; 100 (12): 759-770. PMID: 31845776 pubmed.ncbi.nlm.nih.gov/31845776/.