Ciwan cholangitis

Sclerosing cholangitis na nufin kumburi (kumburi), tabo, da lalata bututun bile ciki da waje na hanta.

Ba a san dalilin wannan yanayin ba a mafi yawan lokuta.

Ana iya ganin cutar a cikin mutanen da ke da:

• Ciwon hanji mai kumburi (IBD) irin su ulcerative colitis da Crohn disease
  
• Rashin lafiyar Autoimmune
• Na kullum pancreatitis (inflamed pancreas)
• Sarcoidosis (cutar da ke haifar da kumburi a sassa daban-daban na jiki)

Hakanan halayen kwayar halitta na iya zama alhakin. Sclerosing cholangitis ya fi faruwa a cikin maza fiye da mata. Wannan cuta ba ta da yawa a cikin yara.

Hakanan za'a iya haifar da sclerosing cholangitis ta:

• Choledocholithiasis (gallstones a cikin bile bututu)
• Cututtuka a cikin hanta, gallbladder, da bile ducts

Na farko bayyanar cututtuka yawanci:

• Gajiya
• Itching
• Yellowing na fata da idanu (jaundice)

Koyaya, wasu mutane basu da alamun bayyanar.

Sauran cututtuka na iya haɗawa da:

• Liverara hanta
• Pleara girman ciki
• Rashin ci da rage nauyi
• Maimaita aukuwa na cholangitis

Kodayake wasu mutane ba su da alamun cutar, gwajin jini yana nuna cewa suna da aikin hanta mara kyau. Mai ba ku kiwon lafiya zai nema:

• Cututtukan da ke haifar da irin wannan matsalar
• Cututtukan da galibi ke faruwa da wannan yanayin (musamman IBD)
• Duwatsu masu tsakuwa

Gwajin da ke nuna cholangitis sun hada da:

• CT scan na ciki
• Ciki duban dan tayi
• Endoscopic retrograde cholangiopancreatography (ERCP)
• Gwajin hanta
• Magnetic rawa cholangiopancreatography (MRCP)
• Ercwararren ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa (PTC)

Gwajin jini sun hada da enzymes na hanta (gwajin aikin hanta).

Magungunan da za'a iya amfani dasu sun haɗa da:

• Cholestyramine (kamar Prevalite) don magance itching
• Ursodeoxycholic acid (ursodiol) don inganta aikin hanta
• Mai bitamin mai narkewa (D, E, A, K) don maye gurbin abin da aka rasa daga cutar kanta
• Magungunan rigakafi don magance cututtuka a cikin hanyoyin bile

Wadannan hanyoyin aikin za a iya yi:

• Saka dogon, siririn bututu tare da baloon a karshen don buɗe takaitawa (ƙarar ƙirar balloon na tsananin)
• Sanya magudanar ruwa ko bututu don ƙuntataccen (tsaurara matakai) na bututun bile
• Proctocolectomy (cirewar hanji da dubura, ga waɗanda suke da ciwon ulcerative colitis da sclerosing cholangitis) baya shafar ci gaban cutar sclarosing cholangitis ta farko (PSC)
• Dasawa na hanta

Yadda mutane suke yi ya bambanta. Cutar na neman yin muni a kan lokaci. Wani lokaci mutane suna haɓaka:

• Ascites (gina ruwa a sararin samaniya tsakanin rufin ciki da gabobin ciki) da juzu'i (faɗaɗa jijiyoyi)
• Biliary cirrhosis (kumburi daga cikin bile ducts)
• Rashin hanta
• Jaundice mai ɗorewa

Wasu mutane suna kamuwa da cututtukan bile wanda ke ci gaba da dawowa.

Mutanen da ke cikin wannan yanayin suna da babban haɗarin kamuwa da cutar kansa ta bile ducts (cholangiocarcinoma). Yakamata a duba su akai-akai tare da gwajin hoto na hanta da gwajin jini. Mutanen da ke da IBD na iya samun ƙarin haɗarin kamuwa da ciwon daji na hanji ko dubura kuma ya kamata su yi ta binciken ƙwaƙwalwa na lokaci-lokaci.

Matsaloli na iya haɗawa da:

• Zubar jini a jiki
• Ciwon daji a cikin bututun bile (cholangiocarcinoma)
• Cirrhosis da gazawar hanta
• Kamuwa da cuta daga biliary tsarin (cholangitis)
• Rage hanyoyin bututun bile
• Rashin bitamin

Primary sclerosing cholangitis; PSC

• Tsarin narkewa
• Hanyar Bile

Bowlus C, Assis DN, Goldberg D. Primary da sakandare sclerosing cholangitis. A cikin: Sanyal AJ, Boyer TD, Lindor KD, Terrault NA, eds. Zakim da Boyer's Hepatology. 7th ed. Philadelphia, PA: Elsevier; 2018: babi na 43.

Ross AS, Kowdley KV. Cutar sclerosing cholangitis na farko da maimaita cutar kwayar cuta. A cikin: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger da cututtukan hanta da cutar Fordtran: Pathophysiology / Diagnosis / Management. 10 ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 68.

Zyromski NJ, Pitt HA. Gudanar da cutar sclerosing cholangitis. A cikin: Cameron JL, Cameron AM, eds. Far Mashi na Yanzu. 12th ed. Philadelphia, PA: Elsevier; 2017: 453-458.