Acromegaly

Acromegaly shine yanayin da akwai haɓakar haɓakar (GH) da yawa a jiki.

Acromegaly yanayi ne mai wuya. Ana haifar dashi lokacin da gland shine yake haifar da hormone mai girma sosai. Gland shine yake shine karamin glandon endocrine wanda yake hade da kasan kwakwalwa. Yana sarrafawa, yin, da kuma sakewa da yawa na hormones, gami da haɓakar girma.

Yawancin lokaci ciwon mara (mara kyau) na gland shine yake sakin hormone mai girma da yawa. A cikin al'amuran da ba safai ba, za a iya gadon cututtukan pituitary.

A cikin yara, GH da yawa yana haifar da gigantism maimakon acromegaly.

Kwayar cututtukan acromegaly na iya haɗawa da ɗayan masu zuwa:

• Warin jiki
• Jini a cikin buta
• Ciwon ramin rami na carpal
• Rage ƙarfin tsoka (rauni)
• Rage hangen nesa na gefe
• Gajiya mai sauƙi
• Heightaramar wuce gona da iri (lokacin da yawan GH ya fara tun yana ƙarami)
• Gumi mai yawa
• Ciwon kai
• Enara ƙarfin zuciya, wanda zai iya haifar da suma
• Rashin tsufa
• Muƙamuƙin jaw
• Raɗaɗin haɗin gwiwa, iyakantaccen motsi na haɗin gwiwa, kumburi daga cikin wuraren da ke kusa da haɗin gwiwa
• Manyan kasusuwa na fuska, manyan muƙamuƙi da harshe, haƙoran da ke tazara sosai
• Manyan ƙafa (canji a girman takalmi), manyan hannaye (canji a zobe ko girman safar hannu)
• Gananan gland a cikin fata (glandes masu laushi) suna haifar da fata mai laushi, kaurin fata, alamun fata (ci gaba)
• Barcin bacci
• Yatsun yatsu ko yatsu, tare da kumburi, ja, da zafi

Sauran alamun da zasu iya faruwa tare da wannan cuta:

• Ciwon hanji
• Girman gashi mai yawa a cikin mata (hirsutism)
• Hawan jini
• Rubuta ciwon sukari na 2
• Kara girman thyroid
• Karuwar nauyi

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamunku.

Za'a iya yin odar gwaje-gwaje masu zuwa don tabbatar da cutar acromegaly da kuma bincika rikitarwa:

• Glucosewar jini
• Ciwon girma da haɓakar haɓakar haɓakar hormone
• Growtharfin haɓakar insulin 1 (IGF-1)
• Prolactin
• -Unƙun rami
• MRI na kwakwalwa, gami da gland
• Echocardiogram
• Ciwon ciki
• Nazarin bacci

Sauran gwaje-gwajen ana iya yin oda don bincika ko sauran glandan na aiki na al'ada.

Yin aikin tiyata don cire ƙwayar cutar pituitary wanda ke haifar da wannan yanayin yakan gyara GH mara kyau. Wani lokaci, ƙari yana da girma don a cire shi gaba ɗaya kuma acromegaly ba ya warkewa. A wannan yanayin, ana iya amfani da magunguna da radiation (radiotherapy) don magance acromegaly.

Wasu mutanen da ke da ciwace-ciwacen da ke da wuyar cirewa ta hanyar tiyata ana kula da su da magunguna maimakon tiyata. Wadannan magunguna na iya toshe samarwar GH daga gland din pituitary ko hana aikin GH a sauran sassan jiki.

Bayan jiyya, kuna buƙatar ganin mai ba ku a kai a kai don tabbatar da cewa gland ɗin yana aiki kullum kuma acromegaly baya dawowa. Ana ba da shawarar kimantawar shekara-shekara.

Waɗannan albarkatun na iya samar da ƙarin bayani game da acromegaly:

• Cibiyar Nazarin Ciwon Suga ta Duniya da Cututtukan narkewar abinci da Koda - www.niddk.nih.gov/health-information/endocrine-diseases/acromegaly
• Nationalungiyar forasa don Rare Rashin Lafiya - rarediseases.org/rare-diseases/acromegaly

Yin aikin tiyata yana samun nasara a cikin mafi yawan mutane, ya danganta da girman ƙari da ƙwarewar ƙwararren ƙwararren ƙwararren ƙwayar cuta tare da ciwan ƙwarjin ƙugu.

Ba tare da magani ba, alamun cutar za su kara muni. Yanayi kamar su hawan jini, ciwon sukari, da cututtukan zuciya na iya haifar.

Kira mai ba da sabis idan:

• Kuna da alamun acromegaly
• Kwayoyin ku ba su inganta tare da magani

Ba za a iya hana Acromegaly ba. Jiyya na farko na iya hana cutar ci gaba da zama mai rauni kuma ta taimaka guje wa matsaloli.

Somatotroph adenoma; Girma hormone girma; Hormone na ci gaba yana ɓoye adenoma pituitary; Gwarzo mai girma (a yarinta)

• Endocrine gland

Katznelson L, Dokokin ER Jr, Melmed S, et al. Acromegaly: jagorar tsarin aikin likita na al'umma. J Clin Endocrinol Metab. 2014; 99 (11): 3933-3951. PMID: 25356808 www.ncbi.nlm.nih.gov/pubmed/25356808.

Klein I. Endocrine cuta da cututtukan zuciya. A cikin: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald ta Cutar Cutar: Littafin rubutu na Magungunan zuciya da jijiyoyin jini. 10 ed. Philadelphia, PA: Elsevier Saunders; 2015: babi na 81.

Melmed S. Acromegaly. A cikin: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Manya da Yara. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: sura 12.