Ciwon Fanconi

Ciwon Fanconi cuta ce da ke haifar da bututun koda wanda wasu ƙwayoyin da kodayaushe ke shiga cikin jini ta hanyar koda suna sakin cikin fitsarin maimakon.

Ciwon Fanconi na iya haifar da lalatattun kwayoyin halitta, ko kuma yana iya haifar daga baya a rayuwa saboda lalacewar koda. Wani lokaci ba a san musabbabin ciwon Fanconi ba.

Abubuwan da ke haifar da ciwon Fanconi a cikin yara sune lahani na kwayar halitta waɗanda ke shafar ikon jiki don ragargaza wasu mahaɗan kamar:

• Cystine (cystinosis)
• Fructose (rashin haƙuri fructose)
• Galactose (galactosemia)
• Glycogen (cututtukan glycogen)

Cystinosis shine mafi yawan dalilin cututtukan Fanconi a cikin yara.

Sauran abubuwan da ke haifar da yara sun haɗa da:

• Bayyanawa ga ƙananan ƙarfe kamar gubar, mercury, ko cadmium
• Ciwon Lowe, cuta ce ta kwayar ido, kwakwalwa, da koda
• Cutar Wilson
• Ciwon haƙori, cuta mai rikitarwa ta ƙwayoyin koda

A cikin manya, ana iya haifar da cutar Fanconi ta abubuwa daban-daban waɗanda ke lalata ƙodar, ciki har da:

• Wasu magunguna, gami da azathioprine, cidofovir, gentamicin, da tetracycline
• Dasa koda
• Cutar sarkar haske
• Myeloma mai yawa
• Amyloidosis na farko

Kwayar cutar sun hada da:

• Wucewar fitsari mai yawa, wanda kan haifar da rashin ruwa a jiki
• Thirstishirwa mai yawa
• Ciwo mai tsanani
• Karaya saboda raunin kashi
• Raunin jijiyoyi

Gwajin gwaje-gwaje na iya nuna cewa yawancin waɗannan abubuwa masu zuwa na iya ɓacewa a cikin fitsarin:

• Amino acid
• Giyar Bicarbonate
• Glucose
• Magnesium
• Phosphate
• Potassium
• Sodium
• Uric acid

Rashin waɗannan abubuwa na iya haifar da matsaloli iri-iri. Testsarin gwaje-gwaje da gwajin jiki na iya nuna alamun:

• Rashin ruwa saboda yawan fitsari
• Rashin ci gaba
• Osteomalacia
• Rickets
• Rubuta acidosis na koda

Yawancin cututtuka daban-daban na iya haifar da ciwo na Fanconi. Yakamata a bi da abin da ke haifar da cutar da alamun ta kamar yadda ya dace.

Hangen nesa ya dogara da cutar.

Kira mai ba da kiwon lafiya idan kuna da rashin ruwa a jiki ko raunin tsoka.

De Toni-Fanconi-Debré ciwo

• Ciwon jikin koda

Bonnardeaux A, Bichet DG. Rikicin gado na koda tubule. A cikin: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner da Rector na Koda. 11th ed. Philadelphia, PA: Elsevier; 2020: babi na 44.

Foreman JW. Ciwon Fanconi da sauran cututtukan tubule na kusa. A cikin: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. M Clinical Nephrology. Na 6 ed. Philadelphia, PA: Elsevier; 2019: babi na 48.