Gwajin motsa jiki na ACTH

Gwajin gwajin motsa jiki na ACTH yana auna yadda adrenal gland yake amsawa ga adrenocorticotropic hormone (ACTH). ACTH wani sinadari ne wanda ake samarwa a cikin pituitary gland wanda yake kara karfin gland don fitar da wani sinadari da ake kira cortisol.

Gwajin an yi shi ta hanya mai zuwa:

• Jininku ya ja.
• Hakanan zaku karɓi harbi (allura) na ACTH, yawanci cikin tsoka a kafaɗa. ACTH na iya zama nau'i ne na mutum (roba).
• Bayan ko minti 30 ko minti 60, ko duka biyun, ya danganta da yawan ACTH da ka karɓa, jininka ya sake ɗebowa.
• Lab ya binciki matakin cortisol a cikin duk samfuran jini.

Hakanan kuna iya yin wasu gwaje-gwaje na jini, gami da ACTH, a matsayin ɓangare na gwajin jini na farko. Tare da gwajin jini, ƙila za ku iya yin gwajin cortisol na fitsari ko gwajin fitsari 17-ketosteroids, wanda ya haɗa da tattara fitsarin a cikin awanni 24.

Wataƙila kuna buƙatar iyakance ayyuka da cin abinci waɗanda suke da yawa a cikin carbohydrates sa’o’i 12 zuwa 24 kafin gwajin. Ana iya tambayar ku da kuyi azumi na awanni 6 kafin gwajin. Wani lokaci, ba a buƙatar shiri na musamman. Ana iya tambayarka ku daina shan magunguna na ɗan lokaci, kamar su hydrocortisone, wanda zai iya tsoma baki tare da gwajin jinin cortisol.

Lokacin da aka saka allurar don zana jini, wasu mutane suna jin matsakaicin ciwo. Wasu kuma suna jin ƙyalli ko harba. Bayan haka, ƙila za a sami wasu rauni ko ƙwanƙwasa rauni. Wannan da sannu zai tafi.

Allurar cikin kafada na iya haifar da matsakaici zafi ko ƙura.

Wasu mutane suna jin sanyi, damuwa, ko tashin hankali bayan allurar ACTH.

Wannan gwajin zai iya taimakawa wajen tantance ko glandon ku da na pituitary na al'ada ne. Ana amfani dashi mafi yawa lokacin da mai ba da sabis na kiwon lafiya ya yi tunanin kuna da matsalar gland shine, kamar cututtukan Addison ko rashin isassun hanzari. Hakanan ana amfani dashi don ganin idan pituitary da adrenal gland sun warke daga dogon amfani da magungunan glucocorticoid, kamar prednisone.

Ana tsammanin karuwa a cikin cortisol bayan motsawar ACTH ana tsammanin. Matsayin Cortisol bayan motsawar ACTH ya zama ya fi 18 zuwa 20 mcg / dL ko 497 zuwa 552 nmol / L, ya danganta da ƙimar ACTH da aka yi amfani da ita.

Jeri na darajar yau da kullun na iya ɗan bambanta kaɗan tsakanin ɗakunan gwaje-gwaje daban-daban. Wasu ɗakunan gwaje-gwaje suna amfani da ma'aunai daban-daban ko na iya gwada samfuran daban. Yi magana da mai baka game da ma'anar takamaiman sakamakon gwajin ka.

Wannan gwajin yana taimakawa wajen gano ko kuna da:

• Rikicin adrenal mai rikitarwa (yanayin barazanar rai wanda ke faruwa yayin da babu wadatar cortisol)
• Addison cuta (adrenal gland ba ya samar da isasshen cortisol)
• Hypopituitarism (gland na pituitary baya samar da isasshen hormones kamar ACTH)

Akwai 'yar hatsarin da ke tattare da daukar jininka. Jijiyoyi da jijiyoyin jini sun bambanta da girma daga mutum ɗaya zuwa wancan, kuma daga wannan gefe na jiki zuwa wancan. Bloodaukar jini daga wasu mutane na iya zama da wahala fiye da wasu.

Sauran haɗarin da ke tattare da ɗaukar jinni ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Mahara huda don gano wuri jijiyoyinmu
• Hematoma (jini yana taruwa a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

Gwajin adrenal reserve; Cosyntropin gwajin motsawa; Cortrosyn gwajin gwaji; Synacthen gwajin motsawa; Tetracosactide gwajin motsawa

Barthel A, Willenberg HS, Gruber M, Bornstein SR. Rashin ƙarancin adrenal. A cikin: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Manya da Yara. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi 102.

Chernecky CC, Berger BJ. ACTH gwajin gwaji - bincike. A cikin: Chernecky CC, Berger BJ, eds. Gwajin Laboratory da hanyoyin bincike. Na 6 ed. St Louis, MO: Elsevier Saunders; 2013: 98.

Stewart PM, Newell-Price JDC. Tsarin adrenal. A cikin: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Littafin Williams na Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: babi na 15.