Mawallafi: William Ramirez
Ranar Halitta: 18 Satumba 2021
Sabuntawa: 14 Nuwamba 2024
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Resveratrol: dosage and effect on cardiovascular health | David Sinclair
Video: Resveratrol: dosage and effect on cardiovascular health | David Sinclair

Wadatacce

Resveratrol wani sinadari ne wanda ake samu a cikin ruwan inabi ja, fatun inabi ja, ruwan 'ya'yan inabi mai laushi, mulberries, kuma a cikin ƙaramin gyada. Ana amfani dashi azaman magani.

Resveratrol ana amfani dashi mafi yawa don yawan cholesterol, ciwon daji, cututtukan zuciya, da sauran yanayi. Koyaya, babu kwararan hujjoji don tallafawa amfani da resveratrol don waɗannan amfani.

Magunguna na Compwararren Bayanan Bayanai ƙimar tasiri bisa ga shaidar kimiyya bisa ga mizani mai zuwa: Inganci, Mai yuwuwa Mai Yiwuwa, Yiwuwar Tasiri, Yiwuwar Mara Inganci, Mai yiwuwa Mara Inganci, Mara Inganci, da suarancin Shaida don Rate.

Effectivenessimar tasiri don RESVERATROL sune kamar haka:

Yiwuwar tasiri ga ...

  • Hay zazzabi. Amfani da maganin feshin hanci wanda ya kunshi resveratrol sau uku a kullum na tsawon makwanni 4 da alama yana rage alamun rashin lafiyan a manya tare da rashin lafiyar lokaci. Amfani da maganin feshin hanci wanda ya kunshi resveratrol da beta-glucans sau uku a kowace rana na tsawon watanni 2 kuma da alama yana rage alamun rashin lafiyan yara tare da rashin lafiyar lokaci.
  • Kiba. Wasu bincike sun nuna cewa shan resveratrol na iya kara asarar nauyi ga manya masu kiba.

Zai yuwu bashi da tasiri ga ...

  • Ciwon zuciya. Mutanen da ke cinye yawancin abinci na resveratrol da alama ba su da ƙananan haɗarin cututtukan zuciya idan aka kwatanta da mutanen da ke cin ƙananan abubuwa. Hakanan, shan resveratrol da baki ba ze inganta matakan cholesterol ko mai da ake kira triglycerides a cikin mutanen da ke cikin haɗarin kamuwa da ciwon zuciya ba.
  • Ofungiyar alamun bayyanar cututtukan da ke ƙara haɗarin ciwon sukari, cututtukan zuciya, da bugun jini (cututtukan rayuwa). Shan resveratrol ba ze rage karfin jini, suga, ko cholesterol a cikin mutanen da ke fama da ciwo mai illa ba. Binciken farko ya nuna cewa resveratrol na iya taimakawa wajen rage nauyin jiki da kitsen jiki a cikin mutanen da ke fama da ciwo mai illa. Amma ana bukatar karin bincike don tabbatarwa.
  • Ofara kitse a cikin hanta a cikin mutanen da ke shan kaɗan ko kuma ba giya ba (cutar hanta mai haɗari ko NAFLD). Yawancin bincike na farko sun nuna cewa resveratrol baya inganta aikin hanta, ciwon hanta, ko matakan cholesterol a cikin mutanen da ke da NAFLD.

Evidencearancin shaida don kimanta inganci don ...

  • Kuraje. Binciken farko ya nuna cewa shafa gel mai dauke da sinadarin 'resveratrol' a fuska tsawon kwanaki 60 yana rage tsananin fesowar fata.
  • Rage ƙwaƙwalwar ajiya da ƙwarewar tunani waɗanda ke faruwa daidai da shekaru. Babu tabbacin idan resveratrol ya taimaka da ƙwaƙwalwar ajiya ko ƙwarewar tunani a cikin tsofaffi. Wasu bincike na farko sun nuna cewa resveratrol na iya inganta dabarun tunani da ƙwaƙwalwar ajiya a cikin mata bayan sun gama al'ada. Amma wasu bincike sun nuna cewa resveratrol da aka bayar a cikin allurai masu yawa ko na lokaci mai tsawo baya inganta ƙwaƙwalwar ajiya ko ƙwarewar tunani a cikin tsofaffi masu lafiya.
  • Rashin lafiyar jini wanda ke rage matakan furotin a cikin jini da ake kira haemoglobin (beta-thalassaemia). Binciken farko ya nuna cewa shan trans-resveratrol ba ya inganta matakan haemoglobin ko kuma buƙatar ƙarin jini ga mutanen da ke da beta-thalassaemia.
  • Ciwon daji. Mutanen da ke cinye yawancin abinci na resveratrol da alama ba su da ƙananan haɗarin cutar kansa idan aka kwatanta da mutanen da ke cinye kaɗan.
  • Ciwon suga. Wasu bincike sun nuna cewa resveratrol yana inganta kulawar sukari a cikin mutane da ciwon sukari. Amma sauran bincike sun nuna babu fa'ida. Resveratrol na iya taimakawa rage yawan sukarin jini a cikin marasa lafiya kawai wadanda ke da matakan sikarin jini wadanda ba a sarrafa su da kyau. Ana buƙatar ƙarin bincike don tabbatarwa.
  • Lalacewar koda a cikin mutanen da ke fama da ciwon sukari (nephropathy na ciwon sukari). Binciken farko ya nuna cewa shan resveratrol tare da maganin losartan na iya inganta wasu matakan lalacewar koda a cikin mutanen da ke fama da ciwon sukari.
  • Cutar huhu wanda ke sa wahalar numfashi (cututtukan huhu na huhu ko COPD). Binciken farko ya nuna cewa shan kayan hadin da ke dauke da sinadarin resveratrol, bitamin C, zinc, da flavonoids dan kadan yana rage tari da daskarewa a cikin mutanen da ke da COPD. Amma ba a bayyana ba idan amfanin ya kasance ne saboda resveratrol ko wasu sinadaran.
  • Osteoarthritis. Binciken farko ya nuna cewa ƙara resveratrol zuwa daidaitaccen jiyya don gwiwa osteoarthritis na iya inganta ciwo, aiki, da ƙarfi fiye da daidaitattun jiyya shi kaɗai.
  • Inganta hanyar kiwon lafiya da ake kira dialysis. Binciken farko ya nuna cewa resveratrol na iya sanya saurin jini ya tafi da sauri a cikin mutanen da ke fama da wankin ciki.
  • Ciwon rashin kwayar cutar da ke haifar da kara girman ƙwai tare da kumbura (polycystic ovary syndrome ko PCOS). Binciken farko ya nuna cewa resveratrol yana rage testosterone a cikin mata masu PCOS. Amma ba ya inganta nauyi, matakan lipid, kuraje, ko ci gaban gashi da ba a so a cikin mata masu wannan yanayin.
  • Rheumatoid amosanin gabbai (RA). Resaukar resveratrol tare da magunguna don RA da alama yana rage yawan raɗaɗin raɗaɗi da kumbura. Amma ba a sani ba idan resveratrol shima yana taimakawa rage lalacewar haɗin gwiwa.
  • Wani nau'in cututtukan hanji mai kumburi (ulcerative colitis). Binciken farko ya nuna resveratrol na iya inganta alamomin kuma ya rage aikin ulcerative colitis.
  • Fatar tsufa.
  • Rage ƙwaƙwalwar ajiya da ƙwarewar tunani a cikin tsofaffi waɗanda ya fi abin da ke al'ada ga shekarunsu.
  • Eningarfafa jijiyoyin jini (atherosclerosis).
  • Memwaƙwalwar ajiya da ƙwarewar tunani (aikin fahimi).
  • Sauran yanayi.
Ana buƙatar ƙarin shaida don kimanta sake dawowa kan waɗannan amfani.

Resveratrol na iya faɗaɗa magudanar jini kuma ya rage aikin ƙwayoyin cuta masu mahimmanci a cikin ɗaukar jini. Wasu bincike suna ba da shawarar cewa resveratrol yana da raunin estrogen (haɓakar mace). Hakanan yana iya rage zafi da kumburi (kumburi). Resveratrol na iya rage yawan sukari (glucose) a cikin jini kuma ya taimakawa jiki yakar cutar. Hakanan yana iya hana sunadarai a cikin kwakwalwa haɗuwa tare don taimakawa rigakafin cututtuka irin su cutar Alzheimer.

Lokacin shan ta bakin: Resveratrol shine LAFIYA LAFIYA lokacin amfani da adadin da aka samo a cikin abinci. Lokacin da aka sha a cikin allurai har zuwa 1500 MG kowace rana har zuwa watanni 3, resveratrol ne MALAM LAFIYA. Anyi amfani da mafi girman allurai har zuwa 2000-3000 MG a kullun cikin aminci har tsawon watanni 2-6. Koyaya, waɗannan mahimmancin maganin na resveratrol suna iya haifar da matsalolin ciki.

Lokacin amfani da fata: Resveratrol shine MALAM LAFIYA idan aka shafa a fata har zuwa kwana 30.

Kariya & Gargaɗi na Musamman:

Ciki da shan nono: Resveratrol shine LAFIYA LAFIYA lokacin amfani da adadi da aka samu a wasu abinci. Koyaya, yayin daukar ciki da shayarwa, tushen resveratrol yana da mahimmanci. Resveratrol ana samun shi a fatun innabi, ruwan inabi, da sauran hanyoyin abinci. Bai kamata a yi amfani da ruwan inabi a matsayin tushen resveratrol a lokacin daukar ciki da shayar da nono ba.

Yara: Resveratrol shine MALAM LAFIYA a cikin yara lokacin da aka fesa su a cikin hancin har na tsawon watanni 2.

Rashin jini: Resveratrol na iya yin jinkirin daskarewar jini kuma ya haifar da barazanar zub da jini a cikin mutanen da ke da cutar zubar jini.

Halin mai saurin damuwa kamar kansar nono, kansar mahaifa, sankarar jakar kwai, endometriosis, ko mahaifa fibroids: Resveratrol na iya aiki kamar estrogen. Idan kana da kowane irin yanayi wanda zai iya zama mafi muni ta hanyar shafar isrogen, kar kayi amfani da resveratrol.

Tiyata: Resveratrol na iya kara yiwuwar zub da jini yayin da bayan tiyata. Dakatar da amfani da resveratrol akalla makonni 2 kafin a shirya maka aikin tiyata.

Matsakaici
Yi hankali da wannan haɗin.
Magunguna sun canza ta hanta (Cytochrome P450 1A1 (CYP1A1) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna.

Wasu magunguna da hanta ta canza sun haɗa da chlorzoxazone, theophylline, da bufuralol.
Magunguna da hanta suka canza (Cytochrome P450 1A2 (CYP1A2) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna.

Wasu magunguna da hanta ta canza sun hada da clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Tallo) Indran ), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), da sauransu.
Magunguna sun canza ta hanta (Cytochrome P450 1B1 (CYP1B1) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna.

Wasu magunguna da hanta ta canza sun hada da theophylline, omeprazole, clozapine, progesterone, lansoprazole, flutamide, oxaliplatin, erlotinib, da maganin kafeyin.
Magunguna da hanta suka canza (Cytochrome P450 2C19 (CYP2C19) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna.

Wasu magunguna da hanta ta canza sun hada da amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin, da sauran su.
Magunguna sun canza ta hanta (Cytochrome P450 2E1 (CYP2E1) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna.

Wasu magungunan da hanta ta canza sun hada da acetaminophen, chlorzoxazone (Parafon Forte), ethanol, theophylline, da kuma maganin kashe kuzari irin su enflurane (Ethrane), halothane (Fluothane), isoflurane (Forane), methoxyflurane (Penthrane).
Magunguna da hanta suka canza (Cytochrome P450 3A4 (CYP3A4) substrates)
Wasu magunguna ana canza su ta hanta. Resveratrol na iya rage yadda hanta ke saurin wargaza wasu magunguna. A ka'idar, shan resveratrol tare da wasu magungunan da hanta ta karye na iya kara tasiri da illar wasu magunguna. Koyaya, wasu binciken farko sun nuna sakamako mai karo da juna.

Wasu magungunan da hanta ta canza sun hada da wasu masu toshe hanyar tashar kazar (diltiazem, nicardipine, verapamil), magungunan chemotherapeutic (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanilid (Alfenta) ), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Versed), da sauransu.
Magunguna waɗanda ke jinkirta daskarewar jini (Magungunan Anticoagulant / Antiplatelet)
Resveratrol na iya rage daskarewar jini. Shan resveratrol tare da magunguna wanda kuma jinkirin daskarewa na iya kara damar bruising da zub da jini.

Wasu magungunan da ke rage daskarewar jini sun hada da asfirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, wasu), ibuprofen (Advil, Motrin, wasu), naproxen (Anaprox, Naprosyn, wasu), dalteparin (Fragmin), enoxaparin (Lovenox) , heparin, warfarin (Coumadin), da sauransu.
Ganye da kari wadanda zasu iya rage daskarewar jini (Anticoagulant / Antiplatelet herbs and supplements)
Resveratrol na iya rage daskarewar jini. Amfani da shi tare da wasu ganyayyaki ko kari wanda hakan kuma na iya jinkirta daskarewar jini na iya ƙara haɗarin zubar jini ko ƙujewa a wasu mutane. Wadannan ganyayyaki sun hada da Angelica, clove, danshen, feverfew, tafarnuwa, ginger, ginkgo, ginseng Panax, chestnut horse, red clover, turmeric, da sauransu.
Fats da abinci mai dauke da mai
Shan resveratrol tare da abinci mai dauke da kitse na iya rage adadin resveratrol da jiki ke sha.
An yi nazarin ƙwayoyi masu zuwa a cikin binciken kimiyya:

MAGABATA

DA BAKI:
  • Don rashin lafiyar yanayi (hay fever): Feshin ruwa guda biyu na wani ruwa wanda yake 0.1% resveratrol a cikin kowane hancin sau uku / rana har zuwa sati 4.
  • Don kiba: 500 MG ko lessasa da resveratrol kowace rana na tsawon watanni 3 ko fiye.
3,5,4 'TriHydroxy-Transstibene, (E) - 5- (4-hydroxystyryl) benzene-1,3-diol, 3,4', 5-stilbenetriol, 3,5,4 '-trihydroxystilbene, 3,4 ', 5-trihydroxystilbene, 3,5,4'-trihydroxy-trans-stilbene, Cis-Resveratrol, Extrait de Vin, Extrait de Vin Rouge, Kojo-Kon, Phytoalexin, Phytoalexine, Phytoestrogen, Phyto-œstrogène, Pilule de Vin, Protykin, Red Wine tsantsa, Resvératrol, Resveratrols, Resvératrols, RSV, RSVL, Stilbene Phytoalexin, Trans-Resveratrol, Trans-Resvératrol, Wine Cire, Wine kwaya.

Don ƙarin koyo game da yadda aka rubuta wannan labarin, da fatan za a duba Magunguna na Compwararren Bayanan Bayanai hanya.


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