Darunavir

Wadatacce

• Kafin shan darunavir,
• Darunavir na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:
• Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, ku daina shan darunavir kuma ku kira likitanku nan da nan ko ku sami magani na gaggawa:

Ana amfani da Darunavir tare da ritonavir (Norvir) da sauran magunguna don magance kwayar cutar kanjamau (HIV) ga manya da yara yan shekaru 3 zuwa sama. Darunavir yana cikin ajin magunguna wanda ake kira masu hana yaduwar cutar. Yana aiki ne ta rage adadin kwayar HIV a cikin jini. Kodayake darunavir baya warkar da kwayar cutar kanjamau, amma yana iya rage damarka ta bunkasa cututtukan rashin ƙarfi (AIDS) da cututtukan da ke da alaƙa da HIV kamar cututtuka masu tsanani ko kansa. Shan waɗannan magunguna tare da yin amintaccen jima'i da yin wasu canje-canje na rayuwa na iya rage haɗarin watsa kwayar cutar HIV zuwa wasu mutane.

Darunavir ya zo a matsayin kwamfutar hannu da dakatarwar baka (ruwa) don ɗauka ta baki. Yawanci ana ɗaukarsa da abinci kuma tare da ritonavir sau ɗaya ko sau biyu a rana. Darauki darunavir a kusan lokaci guda (s) kowace rana. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Darauki darunavir daidai yadda aka umurta. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Kar ku ɗauki darunavir ba tare da ritonavir ba.

Ki hadiye allunan duka tare da abin sha kamar ruwa ko madara. Kada a tauna allunan.

Girgiza dakatarwar da kyau dama kowane amfani don haɗa magungunan daidai. Yi amfani da sirinji na allurar baka wanda ya zo tare da magani don janye adadin dakatarwa daidai daga kwalban. Kuna iya haɗiye dakatarwar kai tsaye daga sirinji. Wanke sirinji da ruwa ka barshi ya bushe sosai bayan an yi amfani da shi.

Darunavir yana sarrafa cutar kanjamau amma baya warkar dashi. Ci gaba da shan darunavir koda kuwa kuna cikin koshin lafiya. Kada ka daina shan darunavir ba tare da yin magana da likitanka ba. Idan ka daina shan darunavir ko tsallake allurai, yanayinka na iya zama da wahalar magani. Lokacin da wadatar ka ta darunavir ta fara rauni, saika samu daga likitanka ko likitan magunguna.

Tambayi likitan ko likitan ku don kwafin bayanan masu sana'anta ga mai haƙuri.

Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan darunavir,

• gaya ma likitan ka da likitan ka idan kana rashin lafiyan darunavir, ritonavir, magungunan sulfa, duk wasu magunguna, ko kuma wani sinadarai a cikin allunan darunavir ko dakatarwa. Tambayi likitan ku game da jerin abubuwan da suka hada da shi ko kuma ba ku da tabbas idan wani magani da ku ke cutar sa shine maganin sulfa.
• gaya wa likitanka idan kuna shan ɗayan magunguna masu zuwa: alfuzosin (Uroxatral); cisapride (Propulsid) (babu a Amurka); dronedarone (Multaq); elbasvir / grazoprevir (Zepatier); magunguna irin na ergot kamar su dihydroergotamine (D.HE 45, Migranal), ergotamine (Ergomar, a Cafergot, a Migergot), da methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Mevacor, a cikin Advicor); lurasidone (Latuda), midazolam (an bayar da shi ta baki); pimozide (Orap); ranolazine (Ranexa); rifampin (Rifadin, Rimactane, a cikin Rifamate, a cikin Rifater); sildenafil (kawai alamar Revatio da ake amfani da ita don cutar huhu); simvastatin (Zocor, a cikin Vytorin); St. John’s wort; ko triazolam (Halcion). Likitanku zai iya gaya muku kar ku ɗauki darunavir. Hakanan, idan kuna da cutar koda ko hanta kuma kuna shan colchicine (Colcrys, Mitigare, a cikin Col-Probenecid), mai yiwuwa likitanku zai gaya muku kada ku sha darunavir.
• gaya wa likitanka da likitan kantin ku wasu irin takaddun magani da magunguna marasa magani, bitamin, da kayan abinci mai gina jiki da kuke sha ko shirin sha. Tabbatar da ambaci wani daga cikin masu zuwa: masu hana yaduwar jini (‘masu kara jini)’ kamar su apixaban (Eliquis), rivaroxaban (Xarelto), da warfarin (Coumadin, Jantoven); antifungals kamar su itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), da voriconazole (Vfend); artemether / lumefantrine (Coartem); masu hana beta kamar su carvedilol (Coreg), metoprolol (Lopressor, Toprol XL, a Dutoprol, a Lopressor HCT), da timolol (Betimol, Istalol, a Combigan, a Cosopt, wasu); betamethasone; boceprevir (ba a samun shi a cikin Amurka; Victrelis); bosentan (Tracleer); budesonide (Entocort, Pulmicort, Uceris, wasu); buprenorphine (Belbuca, Buprenex, Butrans, a cikin Suboxone,wasu); buprenorphine / naloxone (Bunavail, Suboxone, Zubsolv); buspirone; masu toshe tashoshin calcium kamar su amlodipine (Norvasc, a Caduet), diltiazem (Cardizem CD, Cartia, XT, Diltzac, wasu), felodipine (Plendil), nicardipine (Cardene), nifedipine (Adalat CC, Afebitab CR, Procardia), da verapamil (Calan, Covera, Verelan, a cikin Tarka); wasu magunguna na chemotherapy kamar su dasatinib (Sprycel), nilotinib (Tasigna), vinblastine, da vincristine (Marqibo Kit); magungunan rage cholesterol (statins) kamar atorvastatin (Lipitor, in Caduet), pravastatin (Pravachol), da rosuvastatin (Crestor); ciclesonide (Alvesco); clarithromycin (Biaxin, a cikin Prevpac); wasu magunguna don damuwa kamar amitriptyline, desipramine (Norpramin), imipramine, nortriptyline, paroxetine (Brisdelle, Paxil, Pexeva), sertraline (Zoloft), da trazodone; dexamethasone; diazepam (Diastat, Valium); estazolam; fentanyl (Abstral, Duragesic, Subsys); fluticasone (Flonase, Flovent, a cikin Advair); wasu magunguna don cutar hepatitis C virus (HCV) kamar glecaprevir / pibrentasvir (Mavyret) da simeprevir (ba a samunsa a Amurka; Olysio); wasu magunguna don cutar kanjamau ciki har da indinavir (Crixivan), lopinavir / ritonavir (Kaletra), maraviroc (Selzentry), da saquinavir (Invirase); maganin hana haihuwa na hormonal (estrogen) (kwayoyin hana haihuwa, faci, zobe, implants, ko allura); magunguna don bugun zuciya mara kyau wanda ya haɗa da amiodarone (Nexterone, Pacerone), bepridil (babu su yanzu a Amurka), digoxin (Lanoxin), disspyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), da quinidine (a Nuedexta ); wasu magunguna don kamuwa kamar carbamazepine (Carbatrol, Equetro, Tegretol, wasu), clonazepam (Klonopin), phenobarbital, da phenytoin (Dilantin, Phenytek); wasu magungunan da ke danne tsarin garkuwar jiki kamar su cyclosporine (Gengraf, Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune), da tacrolimus (Astagraf XL, Prograf); methadone (Dolophine, Methadose); methylprednisolone; mometasone (Asmanex); omeprazole (Prilosec); oxycodone (Xtampza); wasu masu hana foshodiesterase (PDE-5 inhibitors) da aka yi amfani da su wajan lalata kamar avanafil (Stendra), sildenafil (Viagra), tadalafil (Cialis), da vardenafil (Levitra, Staxyn); labaran rana; prednisone (Rayos); quetiapine (Seroquel); rifabutin (Mycobutin); rifapentine (Priftin); risperidone (Risperdal); salmeterol (Serevent, a cikin Advair); tadalafil (Adcirca); sabarini; ticagrelor (Brilinta); tramadol (Conzip); triamcinolone (Nasacort); da zolpidem (Ambien, Edluar, Intermezzo). Sauran magunguna da yawa na iya yin ma'amala da darunavir, don haka tabbatar da gaya wa likitanka duk magungunan da kuke sha, har ma waɗanda ba su bayyana a wannan jeri ba. Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa.
• idan kuna shan didanosine (Videx), ɗauki sa'a 1 kafin ko awa 2 bayan kun sha darunavir.
• gaya wa likitanka idan kana da ko ka taba ciwon sukari ko hawan jini; hemophilia (cuta ta jini wanda jini baya daskarewa yadda yakamata); hepatitis (kumburin hanta da kwayar cuta ta haifar), cirrhosis (cuta ce da ke haifar da tabon hanta), ko kuma duk wata cutar hanta; ko kamuwa da cuta wanda baya tafiya ko wanda yazo ya tafi kamar cytomegalovirus (CMV; kamuwa da kwayar cuta da ka iya haifar da alamomi ga marasa lafiya masu rauni a garkuwar jikinsu), mycobacterium avium hadaddiyar cuta (MAC; kamuwa da cuta na kwayan cuta wanda zai iya haifar da mummunan cututtuka mutanen da ke ɗauke da cutar kanjamau), ciwon huhu, ko tarin fuka (TB; wani nau'in huhun huhu).
• gaya wa likitanka idan kana da juna biyu, shirya yin ciki, ko kuma shayarwa. Idan kun kasance ciki yayin shan darunavir, kira likitan ku. Kada a shayar da nono idan kuna dauke da kwayar cutar HIV ko kuna shan darunavir.
• ya kamata ku sani cewa darunavir na iya rage tasirin maganin hana daukar ciki na ciki (kwayoyin hana haihuwa, faci, zobe, allura, ko implants). Yi magana da likitanka game da tsarin haihuwa na ba na hormonal ba kamar hanyar shinge (na'urar da ke toshe maniyyi daga shiga mahaifa kamar kwaroron roba ko diaphragm) don hana ɗaukar ciki yayin da kuke shan wannan magani. Tambayi likitanku don taimaka muku zaɓi hanyar hana haihuwa wanda zai yi muku aiki.
• ya kamata ku sani cewa kitsen jikinku na iya ƙaruwa ko motsawa zuwa wurare daban-daban na jikinku kamar ƙirjinku, babba baya, wuya, kirji, da yankin ciki. Rashin kitse daga ƙafa, hannaye, da fuska kuma na iya faruwa.
• ya kamata ku sani cewa kuna iya fuskantar hyperglycemia (ƙaruwa a cikin jinin ku) yayin shan wannan magani, koda kuwa baku da ciwon suga. Faɗa wa likitanka kai tsaye idan kana da ɗayan waɗannan alamun yayin da kake shan darunavir: ƙishirwa mai yawa, yawan fitsari, yunwa mai tsanani, hangen nesa, ko rauni. Yana da matukar muhimmanci ka kira likitanka da zaran ka samu irin wadannan alamun, saboda yawan hawan jini da ba a kula da shi na iya haifar da mummunan yanayi da ake kira ketoacidosis. Ketoacidosis na iya zama barazanar rai idan ba a bi da shi a farkon matakin ba. Kwayar cutar ketoacidosis sun hada da: bushewar baki, tashin zuciya da amai, yawan numfashi, numfashin da ke warin 'ya'yan itace, da rage hankali.
• Ya kamata ka sani cewa yayin da kake shan magunguna don magance cutar kanjamau, garkuwar jikinka zata ƙara ƙarfi ta fara yaƙi da wasu cututtukan da suke jikinka. Wannan na iya haifar da ci gaba da bayyanar cututtukan. Idan kana da sababbi ko munanan alamu a kowane lokaci yayin jiyya tare da darunavir, ka tabbata ka gayawa likitanka.

Yi magana da likitanka game da cin ɗanyen inabi da shan ruwan anab yayin shan wannan magani.

Idan kana shan darunavir sau daya a rana kuma ka rasa wani abu ta hanyar kasa da awanni 12, dauki maganin da aka rasa da zaran ka tuna shi sannan ka dauki kashi na gaba a lokacin da aka tsara. Koyaya, idan kun rasa kashi fiye da awanni 12, ku tsallake kashi da aka rasa kuma ku ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Idan kana shan darunavir sau biyu a rana kuma ka rasa wani kashi ta kasa da awanni 6, dauki maganin da aka rasa da zaran ka tuna shi sannan ka dauki kashi na gaba a lokacin da aka tsara. Koyaya, idan kuka rasa kashi fiye da awanni 6, ku tsallake kashi da aka rasa kuma ku ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Darunavir na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:

• ciwon kai
• gudawa
• amai
• ciwon ciki
• maƙarƙashiya

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, ku daina shan darunavir kuma ku kira likitanku nan da nan ko ku sami magani na gaggawa:

• kurji
• peeling ko blistering fata
• ciwon baki
• ja, kumbura, ƙaiƙayi, ko hawaye
• tsoka ko haɗin gwiwa
• zazzaɓi
• kumburi, taushi, ja, ko wasu alamun kamuwa da cuta
• tashin zuciya
• matsanancin gajiya
• rasa ci
• zafi a cikin ɓangaren dama na ciki
• rawaya fata ko idanu
• kodadde ko kujerun duhu

Darunavir na iya haifar da wasu sakamako masu illa. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.

Idan kun fuskanci mummunan sakamako, ku ko likitanku na iya aika rahoto ga shirin Abinci da Magunguna na Hukumar Kula da Abinci da Magunguna (FDA) na kan layi (http://www.fda.gov/Safety/MedWatch) ko ta waya ( 1-800-332-1088).

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye shi a zafin jiki na ɗaki kuma nesa da yawan zafin rana da danshi (ba cikin gidan wanka ba).

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani. Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Idan ya wuce gona da iri, kira layin taimakon guba a 1-800-222-1222. Hakanan ana samun bayanai akan layi akan https://www.poisonhelp.org/help. Idan wanda aka azabtar ya faɗi, ya kamu, fama da numfashi, ko ba za a iya farkawa ba, nan da nan kira sabis na gaggawa a 911.

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanka zai yi odar wasu gwaje-gwaje don tabbatar da lafiya gare ka ka ɗauki darunavir kuma ka duba martanin jikin ka ga darunavir.

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

• Prezista^®
• Prezcobix^® (dauke da Darunavir, Cobicistat)

• TMC-114