Kwayoyin cuta na Monoclonal: menene su kuma me yasa suke taimakawa magance cututtuka

Wadatacce

• Misalan kwayoyin cuta na monoclonal
• 1. Trastuzumab
• 2. Denosumab
• 3. Obinutuzumab
• 4. Ustequinumab
• 5. Pertuzumab
• Yadda ake Shan Magungunan Magunguna

Magungunan Monoclonal sunadarai ne da tsarin garkuwar jiki ke amfani dasu don ganowa da kuma kawar da jikin baƙi, wanda zai iya zama kwayar cuta, ƙwayoyin cuta ko ma ƙwayoyin cuta. Wadannan sunadaran takamaiman ne, yayin da suka fahimci wani manufa, abinda ake kira antigen, wanda zai kasance a cikin kwayoyin jikinsu. Fahimci yadda tsarin garkuwar jiki yake.

Ocwayoyin cuta na Monoclonal, kamar su denosumab, obinutuzumab ko ustequinumab, alal misali, ana kera su a cikin dakin gwaje-gwaje, galibi iri ɗaya ne da waɗanda ake samu a jikin mutum, wanda zai taimaka wa jiki yaƙar wasu cututtuka. Don haka, gwargwadon abin da aka yi amfani da shi na monoclonal, ana iya amfani da waɗannan magungunan don magance wasu cututtuka masu tsanani kamar osteoporosis, leukemia, plaque psoriasis ko wasu nau'o'in na ciwon daji, kamar su nono ko ƙashin ƙashi, misali.

Misalan kwayoyin cuta na monoclonal

Wasu misalai na kwayoyin cuta na monoclonal sun hada da:

1. Trastuzumab

Wannan kwayar cutar ta monoclonal, da ake tallatawa a matsayin Herceptin, an kirkireshi ne ta hanyar injiniyan kwayar halitta, kuma musamman yana afkawa wani furotin wanda yake a jikin mutane masu wasu cututtukan mama da na ciki. Don haka, wannan maganin ana nuna shi don maganin cutar sankarar mama a matakin farko ko tare da metastasis da kansar ciki a cikin ci gaba.

2. Denosumab

Kasuwa kamar Prolia ko Xgeva, tana cikin abun da ke tattare da kwayar cutar IgG2 ta monoclonal, wanda ke tsoma baki tare da aiwatar da wani takamaiman furotin wanda ke sa kasusuwa su yi ƙarfi, yana rage damar karyawa. Don haka, ana nuna Denosumab don maganin rashi ƙashin kashi, osteoporosis, ƙashin ƙashi ko ciwon daji a ci gaba tare da ƙananan ƙashi (wanda ya bazu zuwa ƙasusuwan).

3. Obinutuzumab

Har ila yau, sanannen kasuwanci kamar Gazyva, yana da a cikin abubuwan da ke tattare da shi wanda ya gano kuma ya haɗa shi da sinadarin CD20, wanda aka samu a saman ƙwayoyin jini ko ƙwayoyin lymphocytes. iya dakatar da mummunan ci gaban farin ƙwayoyin jini wanda ke haifar da wannan cuta.

4. Ustequinumab

Wannan magani kuma ana iya saninsa ta hanyar kasuwanci kamar Stelara kuma ya ƙunshi ɗan adam IgG1 monoclonal antibody, wanda ke hana takamaiman sunadaran da ke da alhakin haifar da psoriasis. Sabili da haka, ana nuna wannan maganin don maganin cutar psoriasis.

5. Pertuzumab

Hakanan ana kiranta da suna Perjeta, ya ƙunshi ƙwayoyin cuta na monoclonal waɗanda ke ɗaure ga mai karɓar haɓakar haɓakar ɗan adam 2 mai karɓar rashi, wanda ke cikin wasu ƙwayoyin kansa, rage gudu ko dakatar da ci gaban su. Don haka, ana nuna Perjeta don maganin ciwon nono.

Yadda ake Shan Magungunan Magunguna

Magunguna tare da Magungunan Monoclonal ya kamata a sha a ƙarƙashin shawarar likita kawai, saboda nau'in antibody da za'a yi amfani da shi da kuma ƙwayoyin da aka ba da shawarar sun dogara da matsalar da za a bi da tsananin ta.

A mafi yawan lokuta, ana amfani da waɗannan magungunan don magance cutar kansa, tunda sune magungunan antineoplastic waɗanda dole ne ayi amfani dasu bisa ga takamaiman umarnin da likita ya bayar kuma ana buƙatar gudanar da su a asibitoci ko wuraren shan magani.