Shin Ibuprofen zai iya tsananta alamun COVID-19?

Wadatacce

• Me yasa ibuprofen zai iya kara cutar?
• Abin da aka sani
• Abin da za a yi idan kuna da alamomi

Amfani da Ibuprofen da sauran cututtukan cututtukan cututtukan ƙwayoyin cuta (NSAIDs) yayin kamuwa da SARS-CoV-2 ana ɗaukarsu amintattu, tun da ba zai yiwu a tabbatar da alaƙar da ke tsakanin amfani da wannan maganin ba da kuma munanan alamun numfashi na CUTAR-annobar cutar 19.

Bugu da kari, binciken da aka gudanar a Isra'ila ^[1] kula da marasa lafiyar da suka yi amfani da ibuprofen na tsawon mako guda kafin a gano cutar COVID-19 kuma a yayin jiyya don saukaka alamomi tare da paracetamol kuma sun gano cewa amfani da ibuprofen ba shi da alaƙa da munin yanayin asibiti.

Don haka, babu wata hujja da ke nuna cewa amfani da ibuprofen na iya ƙara yawan cuta da mace-mace na COVID-19 kuma, sabili da haka, ana amfani da wannan maganin ta hanyar hukumomin lafiya, kuma ya kamata a yi amfani da shi a ƙarƙashin shawarar likita.

Me yasa ibuprofen zai iya kara cutar?

Nazarin da aka buga a mujallar Magungunan numfashi na Lancet ^[2] ya ce ibuprofen na iya kara cutar a cikin mutane da ke dauke da cututtukan da ke dauke da kwayar cutar, saboda wannan magani zai iya kara bayyanar da ACE, wanda shi ne mai karɓa da ke cikin ƙwayoyin mutum kuma wanda ya haɗa da sabon coronavirus. Wannan bayanin ya dogara ne da gaskiyar cewa masu fama da ciwon sukari da masu hawan jini suna da adadi mafi yawa na masu karɓar ACE, an yi amfani da ibuprofen da sauran NSAIDs kuma sun haɓaka COVID-19 mai tsanani.

Wani binciken da aka gudanar tare da berayen masu ciwon suga^[3], inganta inganta amfani da ibuprofen na makonni 8 a ƙananan allurai fiye da shawarar, wanda hakan ya haifar da ƙarin magana na angiotensin-converting enzyme 2 (ACE2) a cikin ƙwayar zuciya.

Wannan enzyme din, ACE2, alama ce ɗayan wuraren shigar ƙwayoyin cuta na dangin coronavirus a cikin ƙwayoyin cuta, kuma saboda wannan dalili, wasu masana kimiyya sunyi tunanin cewa idan har ila yau akwai ƙaruwar bayyanar wannan enzyme a cikin mutane, musamman a cikin huhu, yana yiwuwa kwayar cutar na iya ninka cikin sauri, ta haifar da alamun rashin lafiya mai tsanani.

Abin da aka sani

Duk da karatun da aka fitar game da mummunan alakar da ke tsakanin ibuprofen da COVID-19, Hukumar Lafiya ta Duniya da sauran hukumomin kiwon lafiya sun nuna cewa babu wata hujja ta kimiyya da ke nuna cewa amfani da ibuprofen ba zai kasance da aminci ba, tunda sakamakon da aka gabatar ya dogara ne da zato ba karatun mutum ya kasance zahiri. Bugu da kari, wasu nazarin sun nuna hakan ^[4]:

• Babu wata hujja kai tsaye da ke nuna cewa ibuprofen zai iya mu'amala da SARS-CoV-2;
• Babu wata hujja da ke nuna cewa ibuprofen ne ke da alhakin kara bayyanar enzyme na canzawa angiotensin;
• Wasu a cikin binciken in vitro sun nuna cewa ibuprofen na iya “karya” mai karɓar ACE, yana mai da wahala ga hulɗar membrane-virus ɗin kwayar halitta da rage haɗarin kwayar cutar shiga cikin kwayar ta wannan hanyar;
• Babu wata hujja da ke nuna cewa amfani da ibuprofen na iya tsanantawa ko ƙara haɗarin kamuwa da cuta.

Koyaya, ana buƙatar ƙarin nazarin don tabbatar da rashin dangantaka tsakanin SARS-CoV-2 da yin amfani da ibuprofen ko wasu NSAIDs kuma don tabbatar da amintaccen amfani da waɗannan magungunan.

Abin da za a yi idan kuna da alamomi

Game da ƙananan alamun cutar COVID-19, kamar zazzaɓi, tari mai tsanani da ciwon kai, misali, ban da keɓewa, ana ba da shawarar a tuntuɓi likita don a ba da jagora game da magungunan da za a yi amfani da su alamar, ana iya nuna amfani da paracetamol ko ibuprofen, wanda ya kamata a yi amfani da shi bisa ga shawarar likita.

Koyaya, lokacin da alamun suka fi tsanani, kuma za a iya samun matsala wajen yin numfashi da kuma ciwon kirji, abu mafi kyau shi ne mutum ya je asibiti don a tabbatar da ganewar COVID-19 kuma za a iya fara takamaiman magani. tare da magani, manufar hana wasu rikice-rikice da haɓaka ƙimar rayuwar mutum. Fahimci yadda ake yin magani don COVID-19.