Ivermectin: menene don kuma yadda ake amfani dashi

Wadatacce

• Menene don
• Yadda ake amfani da shi
• 1. Strongyloidiasis, filariasis, kwarkwata da cututtukan fata
• 2. Ciwon mara (Onchocerciasis)
• Matsalar da ka iya haifar
• Wanda bai kamata ya dauka ba
• Ivermectin da COVID-19
• A cikin maganin COVID-19
• A cikin rigakafin COVID-19

Ivermectin magani ne na antiparasitic wanda ke iya gurgunta jiki da inganta kawar da cututtukan da dama, wanda likitan ya nuna musamman game da maganin onchocerciasis, elephantiasis, pediculosis, ascariasis da scabies.

Wannan magani an nuna shi ga manya da yara sama da shekaru 5 kuma ana iya samun su a shagunan sayar da magani, yana da mahimmanci a nemi likita game da amfani da shi, saboda ƙimar zata iya bambanta gwargwadon wanda zai kamu da cutar da kuma nauyin wanda abin ya shafa. .

Menene don

Ivermectin magani ne na antiparasitic wanda aka nuna sosai wajen magance cututtuka da yawa, kamar su:

• Strongarfin ƙarfi mai ƙarfi na hanji;
• Filariasis, wanda aka fi sani da giwa;
• Scabies, wanda kuma ake kira scabies;
• Ascariasis, wanda shine kamuwa da cuta daga cutar mai cutar Ascaris lumbricoides;
• Pediculosis, wanda ke cike da kwarkwata;
• Onchocerciasis, wanda aka fi sani da "makantar kogi".

Yana da mahimmanci ayi amfani da ivermectin bisa ga umarnin likitan, saboda haka yana yiwuwa a hana bayyanar cututtukan da suka shafi ciki kamar gudawa, gajiya, ciwon ciki, ragin nauyi, maƙarƙashiya da amai. A wasu lokuta, suma, nutsuwa, jiri, rawar jiki da amosu na iya bayyana a fatar.

Yadda ake amfani da shi

Ivermectin yawanci ana amfani dashi a cikin kashi ɗaya bisa ga wakilin cutar wanda dole ne a kawar dashi. Ya kamata a sha miyagun ƙwayoyi a cikin komai a ciki, awa ɗaya kafin cin abincin farko na yini. Kada a sha shi da magunguna na ajin barbiturate, benzodiazepine ko ajin valproic acid.

1. Strongyloidiasis, filariasis, kwarkwata da cututtukan fata

Don magance ƙarfi mai ƙarfi, filariasis, ƙoshin lice ko scabies, ya kamata a daidaita matakin da ya dace da nauyinku, kamar haka:

2. Ciwon mara (Onchocerciasis)

Don magance onchocerciasis, gwargwadon shawarar, gwargwadon nauyin, shine kamar haka:

Matsalar da ka iya haifar

Wasu daga cikin cututtukan da zasu iya faruwa yayin magani tare da ivermectin sune gudawa, tashin zuciya, amai, raunin gaba ɗaya da rashin ƙarfi, ciwon ciki, rashin cin abinci ko maƙarƙashiya. Wadannan halayen gaba daya suna da sauki kuma suna wucin gadi.

Bugu da kari, halayen rashin lafiyan na iya faruwa, musamman lokacin shan ivermectin don onchocerciasis, wanda zai iya bayyana tare da ciwon ciki, zazzabi, jiki mai kaushi, jajayen fata akan fata, kumburi a cikin idanu ko fatar ido. Idan waɗannan alamun sun bayyana, yana da kyau a daina amfani da shan magani kuma a nemi taimakon likita kai tsaye ko ɗakin gaggawa mafi kusa.

Wanda bai kamata ya dauka ba

Wannan maganin an hana shi ga mata masu juna biyu, mata masu shayarwa, yara 'yan ƙasa da shekaru 5 ko 15 kilogiram da marasa lafiya da ke fama da cutar sankarau ko asma. Bugu da kari, ya kamata kuma ba za a yi amfani da shi a cikin mutanen da ke da karfin kuzari ga ivermectin ko wani daga cikin sauran abubuwan haɗin da ke cikin tsarin ba.

Ivermectin da COVID-19

Anyi magana game da amfani da sinadarin ivermectin akan COVID-19 a tsakanin masana kimiyya, wannan saboda wannan antiparasitic yana da maganin rigakafin cutar kan kwayar cutar da ke haifar da zazzaɓin zazzaɓi, ZIKA da dengue kuma, sabili da haka, ya kamata ace shima yana da tasiri akan SARS-CoV-2.

A cikin maganin COVID-19

Ivermectin an gwada shi daga masu bincike a Ostiraliya a cikin kwayar halitta cikin vitro, wanda ya nuna cewa wannan abu yana da tasiri wajen kawar da kwayar cutar SARS-CoV-2 cikin awanni 48 kawai ^[1] . Koyaya, waɗannan sakamakon basu isa ba don tabbatar da ingancin sa a cikin mutane, kuma ana buƙatar gwaji na asibiti don tabbatar da ingancin sa na gaske. a cikin rayuwa, kuma ƙara ƙayyade ko maganin warkewar yana da lafiya a cikin mutane.

Nazarin marasa lafiya a asibiti a Bangladesh^[2] da nufin tabbatarwa idan amfani da ivermectin zai zama mai lafiya ga waɗannan marasa lafiya kuma cewa za a sami wani tasiri akan SARS-CoV-2. Saboda haka, an ƙaddamar da waɗannan marasa lafiya zuwa yarjejeniyar kulawa ta kwanaki 5 tare da ivermectin (12 MG) kawai ko guda ɗaya na ivermectin (12 MG) a haɗe tare da wasu magunguna na tsawon kwanaki 4, kuma an kwatanta sakamakon tare da rukunin placebo wanda ya ƙunshi Marasa lafiya 72. A sakamakon haka, masu binciken sun gano cewa amfani da ivermectin shi kadai yana da lafiya kuma yana da tasiri wajen kula da mai sauki COVID-19 a cikin marasa lafiyar manya, duk da haka za a buƙaci ƙarin bincike don tabbatar da waɗannan sakamakon.

Wani binciken da aka gudanar a Indiya da nufin tabbatar ko amfani da ivermectin ta hanyar shaƙar iska zai iya haifar da tasirin cutar kan COVID-19 ^[3], kamar yadda wannan magani ke da damar yin katsalandan tare da jigilar tsarin SARS-CoV-2 zuwa ƙwayoyin halittar mutum, wanda ke haifar da tasirin cutar. Koyaya, wannan sakamako zai yiwu ne kawai tare da babban ƙwayoyin ivermectin (mafi girma fiye da shawarar da aka ba da shawarar don maganin ƙwayoyin cuta), wanda zai iya haifar da tasirin cutar hanta. Don haka, a matsayin madadin manyan ƙwayoyin maganin ivermectin, masu binciken sun ba da shawarar yin amfani da wannan maganin ta hanyar shaƙar iska, wanda zai iya samun kyakkyawan aiki game da SARS-CoV-2, duk da haka wannan hanyar gudanarwar har yanzu tana buƙatar a ci gaba da nazari sosai.

Ara koyo game da magunguna don magance kamuwa da cuta tare da sabon coronavirus.

A cikin rigakafin COVID-19

Baya ga ivermectin da ake nazari a matsayin wani nau'i na magani ga COVID-19, an gudanar da wasu binciken da nufin tabbatar ko amfani da wannan magani zai taimaka wajen hana kamuwa da cuta.

Wani bincike da masu bincike suka yi a Amurka da nufin binciko dalilin da ya sa COVID-19 ke da sababi daban-daban a kasashe da dama ^[5]. A sakamakon wannan binciken, sun gano cewa kasashen Afirka na da raguwar abubuwa sakamakon amfani da magunguna masu yawa, akasari magungunan antiparasitic, gami da ivermectin, saboda karuwar barazanar kamuwa da kwayoyin cutar a wadannan kasashen.

Don haka, masu binciken sun yi imanin cewa amfani da ivermectin na iya rage saurin kwayar cutar da hana ci gaban cutar, amma wannan sakamakon ya dogara ne kawai da daidaito, kuma ba a gudanar da gwajin asibiti ba.

Wani binciken kuma ya ruwaito cewa amfani da sinadarin nanoparticles da ke hade da ivermectin na iya rage maganganun masu karba da ke cikin kwayoyin halittar dan adam, ACE2, wanda ke hade da kwayar, da kuma sunadarin da ke jikin kwayar, yana rage yiwuwar kamuwa da cutar ^[6]. Koyaya, ana buƙatar karin karatu a cikin vivo don tabbatar da sakamako, da kuma nazarin abubuwa masu guba don tabbatar da cewa amfani da ivermectin nanoparticles ba shi da aminci.

Game da amfani da ivermectin a hana, babu cikakken karatu tukuna. Koyaya, don ivermectin yayi aiki ta hana ko rage shigar ƙwayoyin cuta cikin ƙwayoyin cuta, ya zama dole akwai kwayar cuta ta kwayar cuta, saboda haka yana yiwuwa a sami maganin rigakafin ƙwayar maganin.