Ma'aikatan Prokinetic

Wadatacce

• Nau'in Prokinetics
• Bethanechol
• Rashin daidaito
• Metoclopramide

A cikin lafiyayyar hancin mutum, hadiyewa yana haifar da cutar farko. Waɗannan su ne ƙanƙantar da kai da ke motsa abincinka a cikin makogwaro da kuma cikin sauran tsarin narkewar abinci. Hakanan, reflux na gastroesophageal yana haifar da matsin lamba na biyu na murdawar jijiyoyin jiki wanda ke share kashin hanji, tare da tura abinci ta cikin kasan mashin din (LES) zuwa ciki.

Koyaya, a cikin wasu mutane, LES ko dai ta annashuwa ko buɗewa ba tare da bata lokaci ba, ta barin abubuwan ciki, gami da acid, don sake shigar da hanzarin mara. Wannan ana kiransa acid reflux kuma yana iya haifar da bayyanar cututtuka kamar ƙwannafi.

Magunguna na prokinetic, ko prokinetics, magunguna ne waɗanda ke taimakawa wajen sarrafa haɓakar acid. Prokinetics na taimakawa ƙarfafa ƙananan ƙarancin ƙashi (LES) kuma yana haifar da abubuwan cikin ciki da sauri. Wannan yana ba da ɗan lokaci kaɗan don ƙoshin ruwa na acid.

A yau, ana amfani da prokinetics tare da wasu cututtukan reflux na gastroesophageal (GERD) ko magungunan ƙwannafi, kamar su proton pump inhibitors (PPIs) ko masu hana masu karɓar H2. Ba kamar waɗannan magungunan na reflux acid ba, waɗanda ke da aminci koyaushe, ƙwararrun ƙwayoyi na iya zama da lahani, ko ma masu haɗari. Sau da yawa ana amfani da su kawai a cikin mahimman lokuta na GERD.

Misali, ana iya amfani da prokinetics don kula da mutanen da suma ke da ciwon sukari mai dogaro da insulin, ko jarirai da yara tare da raunin hanji mai mahimmanci ko maƙarƙashiya mai ƙarfi wanda ba ya amsa wasu jiyya.

Nau'in Prokinetics

Bethanechol

Bethanechol (Urecholine) magani ne wanda yake motsa mafitsara kuma yana taimaka maka wajen yin fitsari idan kana fuskantar matsala wajen zubarda mafitsarar ka. Yana taimakawa ƙarfafa LES, kuma yana sa cikin ya zama fanko da sauri. Yana kuma taimakawa wajen hana tashin zuciya da amai. Akwai shi a cikin kwamfutar hannu.

Koyaya, amfaninta na iya wucewa ta sakamako mai tasiri na yau da kullun. Sakamakonsa na iya haɗawa da:

• damuwa
• damuwa
• bacci
• gajiya
• matsalolin jiki irin su motsin rai da motsa jiki

Rashin daidaito

Cisapride (Propulsid) yana aiki akan masu karɓa na serotonin a cikin ciki. Anyi amfani dashi da farko don haɓaka sautin tsoka a cikin LES. Koyaya, saboda illolinsa, kamar bugun zuciya mara kyau, an cire shi daga kasuwa a ƙasashe da yawa, ciki har da Amurka. Anyi la'akari dashi sau ɗaya azaman mai tasiri a cikin magance GERD azaman masu hana karɓar mai karɓar H2 kamar famotidine (Pepcid). Cisapride har yanzu ana amfani dashi a likitan dabbobi.

Metoclopramide

Metoclopramide (Reglan) wakili ne na prokinetic wanda aka yi amfani dashi don magance GERD ta hanyar inganta aikin tsoka a cikin ɓangaren hanji. Akwai shi a duka kwamfutar hannu da siffofin ruwa. Kamar sauran maganganu na prokinetics, tasirin metoclopramide yana hana ta sakamako mai illa mai tsanani.

Hanyoyi masu illa na iya haɗawa da haɗarin haɗarin yanayin jijiyoyin jiki kamar su dyskinesia na tardive, wanda ke haifar da sake maimaita motsi. Wadannan illolin an san su faruwa ga mutanen da suka kasance akan maganin fiye da watanni uku. Mutanen da ke shan metoclopramide ya kamata su yi taka-tsan-tsan yayin tuki ko aiki da manyan injuna ko kayan aiki.

Yi aiki tare da likitanka don gano wane shirin magani ya dace da kai. Tabbatar ka bi umarnin da likitanka ya baka. Kira likitan ku idan kun ji kamar magungunan ku sun haifar da mummunan sakamako.