Tyrosine: Fa'idodi, Tasirin Gari da Sashi

Wadatacce

• Menene Tyrosine kuma Me Yake Yi?
• Yana Iya Inganta Ayyukan Hauka a Yanayin Matsaloli
• Zai Iya Taimaka Wadanda ke Tare da Phenylketonuria
• Shaida Game Da Tasirin Sa akan Bakin Ciki Ya Cakuda
• Gurbin Taron
• Monoamine Oxidase Inhibitors (MAOIs)
• Hormone na thyroid
• Levodopa (L-dopa)
• Yadda ake kari da Tyrosine
• Layin .asa

Tyrosine sanannen ƙarin kayan abinci ne wanda ake amfani dashi don haɓaka faɗakarwa, kulawa da kuma mai da hankali.

Yana samar da mahimman ƙwayoyin sunadarai na kwakwalwa waɗanda ke taimakawa ƙwayoyin jijiyoyin sadarwa kuma yana iya ma daidaita yanayi ().

Duk da waɗannan fa'idodin, ƙari tare da tyrosine na iya samun sakamako masu illa da ma'amala da magunguna.

Wannan labarin yana gaya muku duk abin da kuke buƙatar sani game da tyrosine, gami da fa'idodi, illolin da kuma abubuwan da aka ba da shawarar.

Menene Tyrosine kuma Me Yake Yi?

Tyrosine amino acid ne wanda ake samar dashi a jiki daga wani amino acid din da ake kira phenylalanine.

An samo shi a cikin abinci da yawa, musamman a cikin cuku, inda aka fara gano shi. A zahiri, "tyros" na nufin "cuku" a Girkanci ().

Hakanan ana samunsa a cikin kaza, turkey, kifi, kayayyakin kiwo da sauran mafi yawan abinci mai gina jiki ().

Tyrosine yana taimakawa yin abubuwa masu mahimmanci, gami da (4):

• Dopamine: Dopamine tana tsara ladan ku da cibiyoyin jin daɗi. Wannan mahimmin sinadarin kwakwalwa yana da mahimmanci don ƙwaƙwalwa da ƙwarewar motsi ().
• Adrenaline da noradrenaline: Wadannan sinadarai na homon suna da alhakin yakin-ko-jirgin zuwa yanayin damuwa. Suna shirya jiki don “yaƙi” ko “tsere” daga haɗarin da aka hango ko cutarwa ().
• Hanyoyin hormones na thyroid: Ana haifar da hormones na thyroid ta glandar thyroid kuma da farko ke da alhakin tsara metabolism ().
• Melanin: Wannan launin yana ba fata, gashi da idanun su launin su. Mutane masu launin fata suna da melanin a cikin fatarsu fiye da masu haske ().

Hakanan ana samunsa azaman abincin abincin. Kuna iya siyan shi shi kaɗai ko haɗuwa tare da sauran abubuwan haɗi, kamar a cikin ƙarin aikin motsa jiki.

Thoughtarin tare da tyrosine ana tsammanin ƙara matakan neurotransmitters dopamine, adrenaline da norepinephrine.

Ta hanyar haɓaka waɗannan ƙananan ƙwayoyin cuta, yana iya taimakawa haɓaka ƙwaƙwalwar ajiya da aiki a cikin yanayin damuwa (4).

Takaitawa Tyrosine amino acid ne wanda jiki yake samarwa daga phenylalanine. Thoughtarin tare da shi ana tsammanin ƙara ƙarfafan sunadarai na kwakwalwa, wanda ke shafar yanayin ku da martani na damuwa.

Yana Iya Inganta Ayyukan Hauka a Yanayin Matsaloli

Danniya wani abu ne da kowa ya dandana.

Wannan damuwa zai iya shafar tunaninku, ƙwaƙwalwarku, hankalinku da iliminku ta hanyar rage ƙwayoyin cuta (,).

Misali, berayen da suka kamu da sanyi (matsin lamba ga muhalli) sun sami nakasu saboda ƙwaƙwalwa a cikin ƙwayoyin cuta (10,).

Koyaya, lokacin da aka ba waɗannan entsan sanduna ƙarin haɓakar tyrosine, raguwar ƙwayoyin cuta sun juya kuma an maido da ƙwaƙwalwar ajiyar su.

Duk da yake bayanan rodent ba lallai bane ya fassara wa mutane, karatun ɗan adam ya sami irin wannan sakamakon.

A cikin wani bincike a cikin mata 22, tyrosine ya inganta ƙwaƙwalwar ajiyar aiki yayin aikin da ke buƙatar tunani, idan aka kwatanta da placebo. Memorywaƙwalwar aiki yana taka muhimmiyar rawa a cikin maida hankali da bin umarni ().

A cikin irin wannan binciken, an ba mahalarta 22 ko dai ƙarin tyrosine ko placebo kafin kammala gwajin da aka yi amfani da shi don auna sassaucin fahimi. Idan aka kwatanta da placebo, an sami tyrosine don haɓaka sassaucin tunani ().

Flexibilitywarewar hankali shine ikon canzawa tsakanin ɗawainiya ko tunani. Saurin da mutum zai iya canza ayyukan, ya fi girma da sauƙin fahimtarsu.

Bugu da ƙari, an nuna ƙarin tare da tyrosine don amfanar waɗanda ke rashin barci. Doseauki guda ɗaya daga ciki ya taimaka wa mutanen da suka rasa barci na dare su kasance masu faɗakarwa na sa'o'i uku fiye da yadda za su iya in ba haka ba ().

Abin da ya fi haka, sake dubawa guda biyu sun yanke shawarar cewa ƙarin tare da tyrosine na iya canza ƙin tunanin mutum da haɓaka haɓaka a cikin gajeren lokaci, damuwa ko yanayin buƙatun tunani (15,).

Kuma yayin da tyrosine na iya samar da fa'idodi na fahimi, babu wata hujja da ta nuna cewa yana haɓaka aikin mutum cikin jiki (,,).

Aƙarshe, babu wani bincike da yake ba da shawarar cewa ƙarin sinadarin tyrosine in babu mai kawo damuwa zai iya inganta aikin tunani. A takaice dai, ba zai kara maka kwakwalwa ba.

Takaitawa Karatun ya nuna cewa tyrosine na iya taimakawa wajen kula da kwakwalwar ka yayin da aka dauke ka kafin aiki mai wahala. Koyaya, babu wata shaida da cewa ƙarin tare da ita na iya inganta ƙwaƙwalwarku.

Zai Iya Taimaka Wadanda ke Tare da Phenylketonuria

Phenylketonuria (PKU) wani yanayi ne mai saurin yaduwar kwayar halitta sakamakon lalacewa a cikin kwayar halitta wacce ke taimakawa wajen haifar da enzyme phenylalanine hydroxylase ().

Jikinku yana amfani da wannan enzyme don canza phenylalanine zuwa tyrosine, wanda ake amfani dashi don ƙirƙirar ƙwayoyin cuta (4).

Koyaya, ba tare da wannan enzyme ba, jikinku ba zai iya lalata phenylalanine ba, yana haifar da shi ya hau jiki.

Babbar hanyar da za'a bi da PKU ita ce bin abinci na musamman wanda ke iyakance abincin da ke dauke da phenylalanine (20).

Koyaya, saboda an yi tyrosine daga phenylalanine, mutanen da ke da PKU na iya zama masu rauni a cikin tyrosine, wanda zai iya taimakawa ga matsalolin halayya ().

Arin tare da tyrosine na iya zama zaɓi mai mahimmanci don sauƙaƙe waɗannan alamun, amma shaidar a hade take.

A cikin bita daya, masu bincike sun binciko tasirin karin tyrosine tare ko kuma a madadin abincin da aka kayyade na phenylalanine a kan hankali, ci gaba, matsayin abinci, yanayin yawan mace-mace da ingancin rayuwa ().

Masu binciken sun binciki karatu biyu da suka hada da mutane 47 amma ba su sami bambanci tsakanin kari da maganin tyrosine da placebo ba.

Binciken karatu uku da suka hada da mutane 56 suma basu sami wani bambanci mai mahimmanci ba tsakanin haɓakawa tare da tyrosine da kuma wuribo akan sakamakon da aka auna ().

Masu binciken sun yanke shawarar cewa babu wani shawarwari da za a iya bayarwa game da ko karin maganin tyrosine na da tasiri don maganin PKU.

Takaitawa PKU mummunan yanayi ne wanda zai iya haifar da karancin tyrosine. Ana buƙatar ƙarin karatu kafin a ba da shawarwari game da magance shi tare da ƙarin maganin tyrosine.

Shaida Game Da Tasirin Sa akan Bakin Ciki Ya Cakuda

Hakanan an ce Tyrosine tana taimakawa cikin damuwa.

Ana tsammanin ɓacin rai na faruwa yayin da ƙwayoyin cuta a cikin kwakwalwarka suka zama ba su daidaita ba. Ana ba da umarnin yawanci don magance sakewa da daidaita su ().

Saboda tyrosine na iya kara samar da kwayar cutar masu yada jijiyoyin jiki, ana da'awar yin aiki a matsayin mai kwantar da hankula ().

Koyaya, binciken farko bai goyi bayan wannan iƙirarin ba.

A cikin binciken daya, mutane 65 da ke da baƙin ciki sun sami ko dai 100 mg / kg na tyrosine, 2.5 mg / kg na maganin rigakafi na yau da kullun ko placebo kowace rana tsawon makonni huɗu. Tyrosine an sami shi ba tare da wani sakamako mai tasiri ba ().

Bacin rai cuta ce mai rikitarwa da ta bambanta. Wannan mai yiwuwa ne dalilin da yasa ƙarin abinci kamar tyrosine ba shi da tasiri wajen yaƙi da alamun ta.

Koyaya, mutane masu baƙin ciki da ƙananan matakan dopamine, adrenaline ko noradrenaline na iya amfana daga ƙarin tare da tyrosine.

A zahiri, binciken daya tsakanin mutane masu fama da rashi na karancin kwayoyi ya lura cewa tyrosine ta samar da fa'idodi na asibiti ().

Depressionaƙancin ƙwayar dopamine yana halin rashin ƙarfi da ƙarancin dalili ().

Har sai an sami ƙarin bincike, shaidun da ke yanzu ba su goyan bayan ƙarin tare da tyrosine don magance alamun rashin damuwa ().

Takaitawa Tyrosine za a iya canza shi zuwa cikin ƙwayoyin cuta wanda ke shafar yanayi. Koyaya, bincike baya tallafawa kari tare dashi don yaƙar alamun cututtukan ciki.

Gurbin Taron

Tyrosine "an san shi gaba ɗaya a matsayin mai aminci" (GRAS) ta Hukumar Abinci da Magunguna (28).

An inganta shi a cikin aminci na kashi 68 MG a kowace laban (150 MG a kowace kilogiram) na nauyin jiki kowace rana har zuwa watanni uku (15,,).

Yayinda tyrosine ke da aminci ga mafi yawan mutane, yana iya haifar da lahani da ma'amala da magunguna.

Monoamine Oxidase Inhibitors (MAOIs)

Tyramine amino acid ne wanda ke taimakawa wajen daidaita hawan jini kuma ana samun shi ta hanyar lalacewar tyrosine.

Tyramine yana tarawa a cikin abinci lokacin da tyrosine da phenylalanine suka canza zuwa tyramine ta hanyar enzyme a cikin ƙananan ƙwayoyin cuta (31).

Cuku kamar cheddar da shuɗi mai laushi, warke ko shan sigari, kayan waken soya da giya suna ɗauke da matakan tyramine (31).

Magungunan antidepressant da aka sani da monoamine oxidase inhibitors (MAOIs) suna toshe enzyme monoamine oxidase, wanda ke lalata ƙwayar tyramine mai yawa a cikin jiki (,,).

Haɗa MAOIs tare da abinci na babban-tyramine na iya ƙara hawan jini zuwa matakin haɗari.

Koyaya, ba'a sani ba idan ƙari tare da tyrosine na iya haifar da haɓakar tyramine a cikin jiki, don haka taka tsantsan ya zama dole ga waɗanda ke ɗaukar MAOIs (, 35).

Hormone na thyroid

A thyroid hormones triiodothyronine (T3) da kuma thyroxine (T4) taimako tsara girma da kuma metabolism a cikin jiki.

Yana da mahimmanci cewa matakan T3 da T4 ba su da yawa ko ƙasa.

Witharin tare da tyrosine na iya yin tasiri akan waɗannan homon ɗin ().

Wannan saboda tyrosine shine tubalin ginin homon na thyroid, don haka kari tare da shi na iya ɗaga matakan su da yawa.

Sabili da haka, mutanen da ke shan maganin karoid ko kuma yin aiki mai ƙyama ya kamata su yi taka-tsantsan yayin da za a kara su da sinadarin tyrosine.

Levodopa (L-dopa)

Levodopa (L-dopa) magani ne wanda yawanci ake amfani dashi don magance cutar Parkinson ().

A cikin jiki, L-dopa da tyrosine suna gasa don sha a cikin ƙananan hanji, wanda zai iya tsoma baki tare da tasirin kwayar (38).

Sabili da haka, ya kamata a raba ƙwayoyin waɗannan magungunan biyu ta awowi da yawa don kauce wa wannan.

Abin sha'awa, ana binciken tyrosine don sauƙaƙa wasu alamomin da ke haɗuwa da haɓakar haɓaka ga tsofaffi (38,).

Takaitawa Tyrosine yana da lafiya ga yawancin mutane. Koyaya, yana iya ma'amala da wasu magunguna.

Yadda ake kari da Tyrosine

A matsayin kari, ana samun tyrosine a matsayin amino acid mai tsari ko N-acetyl L-tyrosine (NALT).

NALT ya fi mai narkewa ruwa fiye da takwarorinsa na kyauta, amma yana da ƙaramar jujjuya zuwa tyrosine a cikin jiki (,).

Wannan yana nufin cewa zaku buƙaci NALT mafi girma fiye da tyrosine don samun sakamako iri ɗaya, yin fom ɗin kyauta shine zaɓin da aka fi so.

Tyrosine yawanci ana shan shi a cikin allurai na 500-2,000 MG 30-60 mintuna kafin motsa jiki, kodayake fa'idodin sa akan aikin motsa jiki sun kasance marasa mahimmanci (42, 43).

Yana da alama yana da tasiri don kiyaye aikin tunani yayin yanayi mai wahala na jiki ko lokutan rashin bacci lokacin da aka ɗauke su cikin allurai da suka fara daga 45-68 MG a kowace fam (100-150 mg a kowace kilogiram) na nauyin jiki.

Wannan zai zama gram 7-10 na mutum mai nauyin kilo 150 (68.2-kg).

Waɗannan ƙananan allurai na iya haifar da ɓarkewar hanji kuma za a raba su kashi biyu, ɗauki 30 da 60 mintuna kafin wani abin damuwa.

Takaitawa Tyrosine azaman amino acid mai kyauta shine mafi kyawun tsari na kari. An lura da tasirinsa mafi girma na anti-danniya lokacin da aka ɗauka a cikin allurai na 45-68 MG a kowace fam (100-150 MG a kowace kilogiram) na nauyin jiki kusan mintuna 60 kafin faruwar matsala.

Layin .asa

Tyrosine sanannen ƙarin kayan abinci ne wanda ake amfani dashi saboda dalilai daban-daban.

A cikin jiki, ana amfani da shi don yin ƙwayoyin cuta, waɗanda ke raguwa a ƙarƙashin wani lokaci na damuwa ko yanayi mai buƙatar tunani.

Akwai kyakkyawar shaida cewa ƙarin tare da tyrosine yana cika waɗannan mahimman ƙwayoyin cuta da haɓaka aikin tunani, idan aka kwatanta da placebo.

Arin tare da shi an nuna lafiya, koda a cikin ƙananan allurai, amma yana da damar yin hulɗa tare da wasu magunguna, yana da garantin kiyayewa.

Duk da yake tyrosine yana da fa'idodi da yawa, mahimmancinsu bai kasance bayyane ba har sai an sami ƙarin shaida.