Me ke sa Mantle Cell Lymphoma ta bambanta da sauran ƙwayoyin cuta?

Wadatacce

• MCL kwayar B-cell ce wacce ba ta Hodgkin ba
• MCL yana shafar tsofaffi
• MCL ba shi da kyan gani gabaɗaya
• Yana shimfidawa daga yankin alkyabbar
• Yana da alaƙa da takamaiman canjin halittu
• Yana da m kuma da wuya a warke
• Ana iya kulawa da shi tare da hanyoyin kwantar da hankali
• Takeaway

Lymphoma shine ciwon daji na jini wanda ke tasowa a cikin ƙwayoyin lymphocytes, wani nau'in ƙwayar ƙwayar farin jini. Lymphocytes suna taka muhimmiyar rawa a cikin garkuwar jikin ku. Lokacin da suka kamu da cutar kansa, sai su riƙa ninkawa ba ji ba gani kuma su zama ƙari.

Akwai nau'ikan lymphoma iri-iri. Zaɓuɓɓukan magani da hangen nesa sun bambanta daga wani nau'in zuwa wani. Auki ɗan lokaci ka koyi yadda kwayar cutar kwayar halitta ta jiki (MCL) ke kwatankwacin sauran nau'ikan wannan cuta.

MCL kwayar B-cell ce wacce ba ta Hodgkin ba

Akwai manyan nau'ikan lymphoma guda biyu: lymphoma na Hodgkin da lymphoma wadanda ba Hodgkin ba. Akwai fiye da nau'ikan 60 na lymphoma wadanda ba Hodgkin ba. MCL yana ɗaya daga cikinsu.

Akwai manyan nau'ikan lymphocytes guda biyu: T lymphocytes (T cells) da B lymphocytes (B cells). MCL yana shafar ƙwayoyin B.

MCL yana shafar tsofaffi

Dangane da Canungiyar Ciwon Cancer ta Amurka, lymphoma na Hodgkin galibi yana shafar samari, musamman ma mutanen da shekarunsu ba su wuce 20 ba. Ta hanyar kwatanta, MCL da sauran nau'ikan lymphoma wadanda ba Hodgkin sun fi yawa ga tsofaffi. Gidauniyar bincike ta Lymphoma ta ba da rahoton cewa yawancin mutane masu cutar MCL maza ne da suka haura shekara 60.

Gabaɗaya, lymphoma yana ɗaya daga cikin nau'ikan cutar kansa da ta fi shafar yara da matasa. Amma ba kamar wasu nau'o'in lymphoma ba, MCL ba safai ake samun sa ba a cikin samari.

MCL ba shi da kyan gani gabaɗaya

MCL ba shi da yawa fiye da wasu nau'ikan lymphoma. Yana da kimanin kashi 5 cikin 100 na duk maganganun lymphoma, a cewar Canungiyar Ciwon Sanarwar Amurka. Wannan yana nufin MCL yana wakiltar kusan 1 cikin 20 lymphomas.

Kwatantawa, mafi yawan nau'ikan nau'in lymphoma ba na Hodgkin shine yada babban kwayar B-cell, wanda ke dauke da kusan 1 cikin 3 lymphomas.

Saboda yana da ɗan wuya, likitoci da yawa na iya zama ba su da masaniya game da sabon bincike da hanyoyin kulawa na MCL. Lokacin da zai yiwu, ya fi kyau a ziyarci likitan ilimin likita wanda ya ƙware a lymphoma ko MCL.

Yana shimfidawa daga yankin alkyabbar

MCL ya samo sunansa ne daga gaskiyar cewa yana samuwa a cikin yankin alkyabbar kumburin kumburi. Yankin mayafin shine zoben lymphocytes wanda ke kewaye da cibiyar kumburin lymph.

A lokacin da aka gano shi, MCL sau da yawa ya bazu zuwa wasu ƙwayoyin lymph, da sauran ƙwayoyin cuta da gabbai. Misali, yana iya yaduwa zuwa kashin jikin ka, saifa, da hanjin ka. A wasu lokuta ba safai ba, yana iya shafar kwakwalwarka da layin ka.

Yana da alaƙa da takamaiman canjin halittu

Ymunƙarar lymph kumbura sune mafi yawan alamun bayyanar MCL da sauran nau'ikan lymphoma. Idan likitanku yana tsammanin kuna da kwayar cutar lymphoma, za su ɗauki samfurin nama daga kumburin lymph kumburi ko wasu sassan jikinku don bincika.

A karkashin madubin hangen nesa, kwayoyin MCL suna kama da wasu nau'ikan lymphoma. Amma a mafi yawan lokuta, kwayayen suna da alamomin kwayar halitta wadanda zasu iya taimaka wa likitanka sanin irin nau'in kwayar cutar da suke. Don yin ganewar asali, likitanku zai ba da umarnin gwaje-gwaje don bincika takamaiman alamomin kwayoyin da sunadarai.

Hakanan likitan ku na iya yin oda wasu gwaje-gwaje, kamar su CT scan, don sanin ko kansar ta bazu. Hakanan zasu iya yin odar biopsy na kashin jikinka, hanjinka, ko sauran kayan kyallen takarda.

Yana da m kuma da wuya a warke

Wasu nau'ikan lymphoma ba na Hodgkin ba su da ƙananan daraja ko indolent. Wannan yana nufin sun fi girma a hankali, amma a mafi yawan lokuta ba su da magani. Jiyya na iya taimakawa rage jijiyoyin, amma ƙananan ƙwayoyin cuta suna yawan dawowa, ko dawowa.

Sauran nau'ikan lymphoma wadanda ba Hodgkin suna da girma ko fada. Suna da saurin girma da sauri, amma galibi ana warkarwa. Lokacin da jiyya ta farko ta yi nasara, babban lymfoma yawanci baya dawowa.

MCL baƙon abu ne a cikin hakan yana nuna fasalulluka na manya-manyan da ƙananan lymphomas. Kamar sauran manyan ƙwayoyin cuta, yawanci yakan bunkasa da sauri. Amma kamar ƙananan ƙwayoyin lymphomas, yawanci ba shi da magani. Yawancin mutane da ke da cutar MCL suna shiga cikin gajiya bayan jinyar da suka yi da farko, amma kusan ciwon kansa yana sake dawowa cikin 'yan shekaru.

Ana iya kulawa da shi tare da hanyoyin kwantar da hankali

Kamar sauran nau'o'in lymphoma, ana iya magance MCL tare da ɗayan ko fiye na hanyoyin masu zuwa:

• m jira
• chemotherapy magunguna
• Kwayoyin cuta na monoclonal
• hade chemotherapy da antibody magani da ake kira chemoimmunotherapy
• radiation radiation
• dasa kwayar halitta

Hukumar Abinci da Magunguna (FDA) ta kuma yarda da magunguna huɗu waɗanda ke takamaiman MCL:

• bortezomib (Velcade)
• Fadar Bege (Revlimid)
• ibrutinib (Imbruvica)
• acalabrutinib (Calquence)

Duk waɗannan magungunan an yarda da su don amfani yayin sake dawowa, bayan an riga an gwada wasu jiyya. An kuma amince da Bortezomib a matsayin magani na farko, wanda za a iya amfani da shi kafin sauran hanyoyin. Ana ci gaba da gwaje-gwajen asibiti da yawa don nazarin amfani da lenalidomide, ibrutinib, da acalabrutinib azaman jiyya-layi na farko, suma.

Don ƙarin koyo game da zaɓuɓɓukan maganinku, yi magana da likitanku. Tsarin maganin da aka ba su ya dogara ne da shekarunka da lafiyarka gaba daya, da kuma inda da yadda cutar kansa ke bunkasa a jikinka.

Takeaway

MCL yana da ƙarancin wuya da ƙalubale don magance shi. Amma a cikin 'yan shekarun nan, an kirkiro sabbin hanyoyin kwantar da hankali kuma an amince da su don magance wannan nau'in cutar kansa. Waɗannan sababbin hanyoyin kwantar da hankalin sun inganta rayuwar mutanen da ke da MCL.

Idan za ta yiwu, ya fi kyau ka ziyarci ƙwararren masanin kansar wanda ke da ƙwarewar maganin lymphoma, gami da MCL. Wannan ƙwararren na iya taimaka muku fahimta da auna zaɓuɓɓukan maganin ku.