Dysbetalipoproteinemia na iyali

Dysbetalipoproteinemia na iyali cuta ce da ta shiga tsakanin iyalai. Yana haifar da yawan cholesterol da triglycerides a cikin jini.

Rashin nakasar halitta yana haifar da wannan yanayin. Rashin lahani yana haifar da gina manyan ƙwayoyin lipoprotein wanda ya ƙunshi duka cholesterol da wani nau'in mai da ake kira triglycerides. Cutar na da nasaba da lahani a cikin kwayar halittar apolipoprotein E.

Hypothyroidism, kiba, ko ciwon sukari na iya sa yanayin ya zama mafi kyau. Dalilai masu haɗari ga dangin dysbetalipoproteinemia na iyali sun haɗa da tarihin iyali na rashin lafiya ko cututtukan jijiyoyin jini.

Ba za a iya ganin alamun ba sai shekara 20 ko sama da haka.

Yarin rawaya na kayan mai a cikin fata da ake kira xanthomas na iya bayyana a kan fatar ido, tafin hannu, tafin ƙafa, ko a jijiyoyin gwiwoyi da gwiwar hannu.

Sauran cututtuka na iya haɗawa da:

• Ciwon kirji (angina) ko wasu alamun cututtukan jijiyoyin jini na iya kasancewa a lokacin ƙuruciya
• Cushe ɗan mara ɗaya ko duka biyun yayin tafiya
• Ciwo a yatsun kafa wanda baya warkewa
• Kwatsam kamar bayyanar cututtuka irin su matsalar magana, faɗuwa a gefe ɗaya na fuska, rauni na hannu ko ƙafa, da rashin daidaituwa

Gwaje-gwajen da za'a iya yi don tantance wannan yanayin sun haɗa da:

• Gwajin kwayoyin halitta don apolipoprotein E (apoE)
• Gwajin jini na jini
• Matakan Triglyceride
• Lowananan ƙananan lipoprotein (VLDL) gwajin

Manufar magani ita ce sarrafa yanayi kamar kiba, hypothyroidism, da ciwon sukari.

Yin canje-canje na abinci don rage adadin kuzari, mai ƙamshi, da cholesterol na iya taimakawa rage ƙwayar cholesterol na jini.

Idan matakan cholesterol da triglyceride har yanzu suna da yawa bayan kun canza canjin abinci, mai ba ku kiwon lafiya na iya sa ku ma ku sha magunguna. Magunguna don rage triglyceride na jini da matakan cholesterol sun haɗa da:

• Bile acid-sequestering resins.
• Fibrates (gemfibrozil, fenofibrate).
• Nicotinic acid.
• Statins.
• PCSK9 masu hanawa, kamar alirocumab (Praluent) da evolocumab (Repatha). Wadannan suna wakiltar sabon rukunin kwayoyi ne don magance cholesterol.

Mutanen da ke da wannan yanayin suna da haɗari sosai game da cututtukan jijiyoyin zuciya da cututtukan jijiyoyin jiki.

Tare da magani, yawancin mutane suna iya rage matakan matakan cholesterol da triglycerides.

Matsaloli na iya haɗawa da:

• Ciwon zuciya
• Buguwa
• Cututtukan jijiyoyin jiki
• Bayanin lokaci-lokaci
• Gangrene na ƙananan ƙafa

Kira mai ba ku sabis idan an gano ku da wannan cuta kuma:

• Sabbin alamun ci gaba.
• Kwayar cutar ba ta inganta tare da magani.
• Kwayar cutar tana daɗa taɓarɓarewa.

Nunawa dangin mutanen da ke cikin wannan yanayin na iya haifar da ganowa da magani da wuri.

Yin jinya da wuri da iyakance wasu abubuwan haɗari kamar shan taba na iya taimakawa hana ciwan zuciya da wuri, shanyewar jiki, da toshe hanyoyin jini.

Nau'in III hyperlipoproteinemia; Dearanci ko m apolipoprotein E

• Ciwon jijiyoyin jini

Genest J, Libby P. Rashin lafiyar Lipoprotein da cututtukan zuciya. A cikin: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald na Ciwon Zuciya: Littafin rubutu na Magungunan zuciya da jijiyoyin jini. 11th ed. Philadelphia, PA: Elsevier; 2019: babi na 48.

Robinson JG. Rashin lafiya na maganin ƙwayar cuta. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 195.