Manya Har yanzu cuta

Adult Still cuta (ASD) cuta ce mai saurin gaske wacce ke haifar da zazzaɓi mai zafi, kumburi, da ciwon gaɓo. Yana iya haifar da cututtukan zuciya na dogon lokaci (na kullum).

Adult Still cuta wani mummunan ciwo ne na cututtukan cututtukan yara (JIA), wanda ke faruwa a cikin yara. Manya na iya samun yanayi iri ɗaya, kodayake ba shi da yawa. Hakanan ana kiranta balagagge-farkon Har yanzu cuta (AOSD).

Kasa da 1 daga cikin mutane 100,000 ke haɓaka ASD kowace shekara. Ya fi shafar mata fiye da maza.

Dalilin babba Duk da haka cutar ba a sani ba. Ba a gano abubuwan da ke haifar da cutar ba.

Kusan dukkan mutanen da ke fama da cutar za su sami zazzaɓi, ciwon gabobi, ciwon wuya, da kumburi.

• Hadin gwiwa, zafi, da kumburi gama gari ne. Mafi sau da yawa, yawancin mahaɗa suna aiki a lokaci guda. Sau da yawa, mutanen da ke cikin yanayin suna da taurin gwiwa na haɗin gwiwa wanda ke ɗaukar awanni da yawa.
• Zazzabin yakan zo da sauri sau ɗaya a rana, galibi da rana ko yamma.
• Fuskar fata sau da yawa launuka ce mai ruwan hoda-ruwan hoda kuma tana zuwa tare da zazzabi.

Symptomsarin bayyanar cututtuka sun haɗa da:

• Ciwon ciki da kumburi
• Jin zafi yayin shan numfashi mai zurfin (pleurisy)
• Ciwon wuya
• Ymananan lymph nodes (gland)
• Rage nauyi

Saifa ko hanta na iya zama kumbura. Huhu da kumburin zuciya na iya faruwa.

AOSD ne kawai za'a iya bincikar sa bayan an kawar da wasu cututtukan da yawa (kamar cututtuka da ciwon daji). Kuna iya buƙatar gwaje-gwajen likita da yawa kafin a gano asalin cutar.

Gwajin jiki na iya nuna zazzaɓi, kurji, da amosanin gabbai. Mai ba da sabis na kiwon lafiya zai yi amfani da stethoscope don sauraron canje-canje a cikin sautin zuciyarku ko huhu.

Gwajin jini mai zuwa na iya taimakawa wajen bincikar manya Har yanzu cutar:

• Cikakken ƙidayar jini (CBC), na iya nuna yawan ƙwayoyin jinin farin (granulocytes) da rage adadin jajayen ƙwayoyin jini.
• C-mai amsa furotin (CRP), ma'aunin kumburi, zai kasance mafi girma fiye da al'ada.
• ESR (ƙididdigar ƙira), gwargwadon kumburi, zai kasance mafi girma fiye da al'ada.
• Matsakaicin Ferritin zai yi tsayi sosai.
• Matakan Fibrinogen zai kasance babba.
• Gwajin aikin hanta zai nuna babban matakin AST da ALT.
• Rheumatoid factor da gwajin ANA zasu zama marasa kyau.
• Al'adun jini da nazarin kwayar cuta zai zama mummunan.

Sauran gwaje-gwaje na iya buƙatar don bincika kumburi na gidajen abinci, kirji, hanta, da baƙin ciki:

• Ciki duban dan tayi
• CT scan na ciki
• X-ray na gidajen abinci, kirji, ko yankin ciki (ciki)

Manufar magani ga manya Duk da haka cutar ita ce sarrafa alamun cututtukan zuciya. Aspirin da sauran cututtukan cututtukan cututtukan ƙwayoyin cuta (NSAIDs), irin su ibuprofen, yawanci ana amfani dasu da farko.

Ana iya amfani da Prednisone don lokuta masu tsanani.

Idan cutar ta kasance mai tsanani ko ta ci gaba na dogon lokaci (ya zama na kullum), ana iya buƙatar magungunan da ke hana garkuwar jiki. Wadannan magunguna sun hada da:

• Samun bayanai
• Anakinra (agonist mai karɓa na interleukin-1)
• Tocilizumab (mai hana shigar interleukin 6)
• Tumor necrosis factor (TNF) antagonists kamar etanercept (Enbrel)

A cikin mutane da yawa, bayyanar cututtuka na iya dawowa sau da yawa a cikin fewan shekaru masu zuwa.

Kwayar cututtukan suna ci gaba na dogon lokaci (na yau da kullun) a cikin kashi ɗaya bisa uku na mutanen da ke da manya Har yanzu da cuta.

Wani nau'ikan nau'ikan cutar, wanda ake kira cututtukan kunnawa na macrophage, na iya zama mai tsananin gaske tare da zazzaɓin zazzaɓi, ciwo mai tsanani da ƙarancin ƙwayoyin jinin. Marashin kashin yana da hannu kuma ana buƙatar biopsy don yin ganewar asali.

Sauran rikitarwa na iya haɗawa da:

• Amosanin gabbai a cikin gidajen abinci da yawa
• Ciwon Hanta
• Ciwon mara
• Yaduwar farin ciki
• Saifa fadada

Kira mai ba ku sabis idan kuna da alamun cutar har yanzu.

Idan an riga an gano ku tare da yanayin, ya kamata ku kira mai ba ku idan kuna da tari ko wahalar numfashi.

Babu sanannun rigakafin.

Har yanzu cutar - babba; Babbar-farawa Duk da haka cutar; AOSD; Ciwon Wissler-Fanconi

Alonso ER, Marques AO. Ciwon-farko har yanzu cuta. A cikin: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: babi na 173.

Gerfaud-Valentin M, Maucort-Boulch D, Hot A, et al. Ciwon-manya har yanzu cutar: bayyanuwa, jiyya, sakamako, da kuma dalilai na hangen nesa a cikin marasa lafiya 57. Magunguna (Baltimore). 2014; 93 (2): 91-99. PMID: 24646465 www.ncbi.nlm.nih.gov/pubmed/24646465.

Kaneko Y, Kameda H, Ikeda K, et al. Tocilizumab a cikin marasa lafiya tare da balagaggu-farkon har yanzu cutar ta ƙi zuwa maganin glucocorticoid: bazuwar, makafi biyu, gwajin gwajin wuribo na III. Ann Rheum Dis. 2018; 77 (12): 1720-1729. PMID: 30279267 www.ncbi.nlm.nih.gov/pubmed/30279267.

Organizationungiyar forasa don Rare Rashin Lafiya yanar gizo. Diseasesananan cututtuka.org. Babbar farawa Har yanzu cutar. rarediseases.org/rare-diseases/adult-onset-stills-disease/. An shiga Maris 30, 2019.

Ortiz-Sanjuán F, Blanco R, Riancho-Zarrabeitia L, et al. Inganci na anakinra a cikin ƙin girma-farkon cutar Har yanzu: nazari da yawa na marasa lafiya 41 da kuma nazarin adabi. Magunguna (Baltimore). 2015; 94 (39): e1554. PMID: 26426623 www.ncbi.nlm.nih.gov/pubmed/26426623.