Mphranous nephropathy

Membranous nephropathy cuta ce ta koda wanda ke haifar da canje-canje da kumburi na sifofin cikin koda wanda ke taimakawa wajen tace ɓarna da ruwa. Kumburin na iya haifar da matsaloli tare da aikin koda.

Mphranous nephropathy yana faruwa ne sakamakon kaurin wani ɓangare na membrane na ƙasa mai ɗauke da ido. Brawayar ginshiƙin ƙasa mai ɗaukaka wani ɓangare ne na kodan da ke taimakawa wajen tace sharar gida da ƙarin ruwa daga jini. Ba a san ainihin dalilin wannan kaurin ba.

Braunƙarin glomerular mai kauri baya aiki kullum. A sakamakon haka, yawancin furotin sun ɓace a cikin fitsari.

Wannan yanayin yana daya daga cikin sanadin cututtukan nephrotic. Wannan rukuni ne na bayyanar cututtuka da suka haɗa da furotin a cikin fitsari, ƙarancin furotin na jini, yawan matakan cholesterol, babban matakan triglyceride, da kumburi. Membranous nephropathy na iya zama cutar koda ta farko, ko kuma tana iya kasancewa tare da wasu yanayi.

Wadannan suna kara haɗarin ku ga wannan yanayin:

• Ciwon daji, musamman cutar huhu da ta hanji
• Bayyanawa ga gubobi, gami da zinariya da mercury
• Cututtuka, ciki har da hepatitis B, malaria, syphilis, da endocarditis
• Magunguna, ciki har da penicillamine, trimethadione, da mayuka masu sauƙaƙa fata
• Tsarin lupus erythematosus, cututtukan zuciya na rheumatoid, cututtukan kabari, da sauran cututtukan autoimmune

Rashin lafiyar yana faruwa a kowane zamani, amma yafi yawa bayan shekaru 40.

Kwayar cututtuka sau da yawa ana farawa a hankali a kan lokaci, kuma na iya haɗawa da:

• Edema (kumburi) a kowane yanki na jiki
• Gajiya
• Fitowar fitsari mai kumfa (saboda yawan furotin)
• Rashin cin abinci
• Fitsari, wuce kima da dare
• Karuwar nauyi

Gwajin jiki na iya nuna kumburi (edema).

Nazarin fitsari na iya bayyana yawan furotin a cikin fitsarin. Hakanan akwai wasu jini a cikin fitsarin. Adadin tacewar duniyan nan ("saurin" da kodan yake tsarkake jini) galibi kusan al'ada ce.

Sauran gwaje-gwajen ana iya yin su don ganin yadda kodan ke aiki da kuma yadda jiki yake dacewa da matsalar koda. Wadannan sun hada da:

• Albumin - jini da fitsari
• Nitrogen na jini (BUN)
• Creatinine - jini
• Yarda da halittar
• Lipid panel
• Protein - jini da fitsari

Kwayar koda ta tabbatar da ganewar asali.

Gwaje-gwaje masu zuwa na iya taimakawa wajen gano musabbabin cutar sanyin jiki:

• Antinuclear antibodies gwajin
• DNA mai saurin-biyun, idan gwajin kwayar cutar ta antinuclear tabbatacciya ce
• Gwajin jini don bincika hepatitis B, hepatitis C, da syphilis
• Levelsara matakan
• Gwajin Cryoglobulin

Manufar magani ita ce rage alamun cuta da rage saurin ci gaban cutar.

Kula da hawan jini ita ce hanya mafi mahimmanci don jinkirta lalacewar koda. Manufar shine a kiyaye hawan jini a ko a ƙasa 130/80 mm Hg.

Ya kamata a kula da yawan cholesterol na jini da triglyceride don rage haɗarin atherosclerosis. Koyaya, mai ƙarancin mai, mai ƙarancin cholesterol galibi baya da amfani ga mutanen da ke da ƙananan ƙwayoyin cuta.

Magungunan da ake amfani dasu don magance cututtukan ƙwayoyin cuta sun haɗa da:

• Angiotensin-converting enzyme (ACE) masu hanawa da masu hana karɓar mai karɓa na angiotensin (ARBs) don rage hawan jini
• Corticosteroids da wasu kwayoyi waɗanda ke hana tsarin rigakafi
• Magunguna (mafi yawan lokuta statins) don rage matakan cholesterol da triglyceride
• Magungunan ruwa (diuretics) don rage kumburi
• Masu rage jini don rage haɗarin daskarewar jini a cikin huhu da ƙafafu

Abincin mai ƙananan furotin na iya zama mai taimako. Ana iya ba da shawarar abinci mai ƙarancin furotin (gram 1 na gm na furotin a kowace kilogram [nauyin kilogram] na nauyin jiki kowace rana).

Vitamin D na iya buƙatar maye gurbinsa idan ciwon nephrotic na dogon lokaci ne (na yau da kullun) kuma baya amsa far.

Wannan cutar na kara samun damar daskarewar jini a cikin huhu da kafafu. Za'a iya ba da umarnin rage magungunan jini don hana waɗannan rikice-rikicen.

Hangen nesa ya bambanta, ya danganta da yawan asarar furotin. Zai yuwu akwai lokuta marasa kyauta na bayyanar cututtuka da kuma tashin hankali lokaci-lokaci. Wani lokaci, yanayin yakan tafi, tare da ko ba tare da magani ba.

Mafi yawan mutanen da ke wannan cutar za su sami lahani na koda kuma wasu mutane za su ci gaba da cutar koda.

Matsalolin da zasu iya haifar da wannan cutar sun hada da:

• Rashin ciwan koda
• Tashin ruwa mai zurfin ciki
• Diseasearshen-gama cutar koda
• Ciwon Nephrotic
• Ciwon mara na huhu
• Ciwon koda na jijiyoyin jiki

Kira don alƙawari tare da mai ba da lafiyar ku idan:

• Kuna da alamun cututtukan ƙwayoyin cuta
• Alamun ku na kara muni ko kuma kada ku tafi
• Kuna ci gaba da sababbin bayyanar cututtuka
• Kun rage fitowar fitsari

Saurin magance cuta da gujewa abubuwa waɗanda zasu iya haifar da cututtukan fata na membranous nephropathy na iya rage haɗarin ka.

Membranous glomerulonephritis; GN na Gana; Ramarin glomerulonephritis; Glomerulonephritis - membranous; MGN

• Ciwon jikin koda

Radhakrishnan J, Appel GB. Rikicin duniya da cututtukan nephrotic. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 113.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Cutar farko ta glomerular. A cikin: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner da Rector na Koda. 11th ed. Philadelphia, PA: Elsevier; 2020: babi na 31.

Salant DJ, Cattran DC. Mphranous nephropathy. A cikin: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. M Clinical Nephrology. Na 6 ed. Philadelphia, PA: Elsevier; 2019: sura 20.