Kusa da ƙwayar ƙwayar tubular acidosis

Kusawar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta wata cuta ce da ke faruwa yayin da kodan ba su cire asid daga jini cikin fitsari yadda ya kamata. A sakamakon haka, yawan acid ya kasance a cikin jini (wanda ake kira acidosis).

Lokacin da jiki yayi ayyukanta na yau da kullun, yakan samar da acid. Idan ba a cire wannan ruwan ko cire shi ba, jinin zai zama mai guba sosai. Wannan na iya haifar da rashin daidaiton lantarki a cikin jini. Hakanan yana iya haifar da matsaloli tare da aikin yau da kullun na wasu ƙwayoyin.

Kodan na taimakawa wajen sarrafa sinadarin acid na jiki ta hanyar cire acid daga cikin jini da fitar da shi cikin fitsari. Abubuwan da ke cikin acid a cikin jiki sun lalace ta hanyar abubuwan alkaline, galibi bicarbonate.

Proximal koda tubular acidosis (irin II RTA) ya auku a lokacin da bicarbonate ba yadda ya kamata reabsorbed da koda ta tace tsarin.

Nau'in II RTA ba shi da yawa fiye da nau'in I RTA. Nau'in I ana kuma kiransa disal renal tubular acidosis. Nau'in Na Biyu galibi yana faruwa yayin ƙuruciya kuma yana iya wucewa da kansa.

Abubuwan da ke haifar da nau'in II RTA sun haɗa da:

• Cystinosis (jiki baya iya fasa kayan cysteine)
• Magunguna kamar ifosfamide (magani na chemotherapy), wasu maganin rigakafi waɗanda ba a amfani da su sosai (tetracycline), ko acetazolamide
• Ciwon Fanconi, rikicewar bututun koda wanda wasu abubuwa da kodayaushe ke shiga cikin jini ta hanyar koda suna sakin cikin fitsarin maimakon
• Rashin haƙuri na fructose, cuta wanda a ciki akwai rashin ƙarancin furotin da ake buƙata don lalata 'ya'yan itace fructose
• Myeloma da yawa, nau'in cutar kansa
• Primary hyperparathyroidism, cuta wanda glandon parathyroid a wuyansa ke samar da hormone parathyroid mai yawa
• Ciwon Sjögren, rashin lafiya na autoimmune wanda glandon da ke samar da hawaye da miyau suka lalace
• Cutar Wilson, cuta ce ta gado wacce akwai jan ƙarfe da yawa a cikin kyallen takarda
• Rashin Vitamin D

Kwayar cututtukan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ta haɗu da ɗayan masu zuwa:

• Rikicewa ko raguwar faɗakarwa
• Rashin ruwa
• Gajiya
• Breathingara yawan numfashi
• Osteomalacia (taushin ƙasusuwa)
• Ciwon tsoka
• Rashin ƙarfi

Sauran cututtuka na iya haɗawa da:

• Rage fitowar fitsari
• Ara yawan bugun zuciya ko bugun zuciya mara tsari
• Ciwon tsoka
• Jin zafi a ƙasusuwa, baya, flan, ko ciki
• Lalacewar kwarangwal

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamun.

Gwajin da za'a iya yin oda sun hada da:

• Gas na jini na jini
• Jikin sunadarai
• Matakan pH na jini
• Fitsarin fitsari da gwajin-acid
• Fitsari

Makasudin shine a dawo da daidaiton ruwan acid da daidaiton lantarki a jiki. Wannan zai taimaka wajen magance rikicewar kasusuwa da rage kasadar osteomalacia da osteopenia a cikin manya.

Wasu manya na iya buƙatar magani. Duk yara suna buƙatar maganin alkaline kamar su potassium citrate da sodium bicarbonate. Wannan magani ne wanda ke taimakawa gyaran yanayin acidic na jiki. Maganin yana taimakawa wajen hana kamuwa da cutar kashi wanda yawan asid ya haifar, kamar su rickets, da kuma bada damar girma na yau da kullun.

Hakanan ana amfani dasu masu amfani da Thiazide don adana bicarbonate a cikin jiki.

Yakamata a gyara abin da ke haifar da necrosis wanda yake kusa da kusa idan ana iya samu.

Ana iya buƙatar bitamin D da ƙwayoyin alli don taimakawa rage ƙarancin nakasa wanda ya samo asali daga osteomalacia.

Kodayake ainihin dalilin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta na iya wucewa ta kanta, sakamakon da rikitarwa na iya zama na dindindin ko barazanar rai. Jiyya yawanci ana samun nasara.

Kira mai ba ku sabis idan kuna da alamun rashin lafiyar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta.

Nemi taimakon likita kai tsaye idan ɗayan waɗannan alamun cututtukan gaggawa na gaba sun haɓaka:

• Rage faɗakarwa ko rashin nutsuwa
• Rage hankali
• Kamawa

Yawancin rikice-rikicen da ke haifar da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ba ta hanawa.

Renal tubular acidosis - kusanci; Nau'in II RTA; RTA - kusanci; Renal tubular acidosis nau'in II

• Ciwon jikin koda
• Koda - jini da fitsari suna gudana

Bushinsky DA. Dutse na koda. A cikin: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Littafin Williams na Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: babi na 32.

Dixon BP. Renal tubular acidosis. A cikin: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Littafin koyar da ilimin yara. 21st ed. Philadelphia, PA: Elsevier; 2020: babi na 547.

Seifter JL. Rikicin Acid-base. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi 110.