Amyloidosis na tsarin na biyu

Tsarin amyloidosis na sakandare cuta ne wanda yawancin sunadaran da ba na al'ada ke haɓaka a cikin kyallen takarda da gabobi. Rushewar sunadaran da basu dace ba ana kiran su amyloid adiits.

Secondary na nufin yana faruwa ne saboda wata cuta ko halin da ake ciki. Misali, wannan yanayin yakan faru ne saboda kamuwa da cuta mai dorewa (mai saurin faruwa) ko kumburi. Ya bambanta, amyloidosis na farko yana nufin babu wata cuta da ke haifar da yanayin.

Tsarin yana nufin cewa cutar ta shafi dukkan jiki.

Ba a san ainihin dalilin amyloidosis systemic na biyu ba. Zai yuwu ku iya haifar da amyloidosis na biyu idan kuna da kamuwa da cuta na dogon lokaci ko kumburi.

Wannan yanayin na iya faruwa tare da:

• Ankylosing spondylitis - wani nau'i ne na cututtukan zuciya wanda yawanci yake shafar ƙasusuwa da haɗin gwiwa a cikin kashin baya
• Bronchiectasis - cuta wanda manyan hanyoyin iska a cikin huhu ke lalacewa ta hanyar kamuwa da cuta mai tsanani
• Osteomyelitis na kullum - kamuwa da kashi
• Cystic fibrosis - cutar da ke haifar da danshi, gamsai mai kauri a cikin huhu, hanyar narkar da abinci, da sauran yankuna na jiki, wanda ke haifar da kamuwa da cutar huhu
• Zazzaɓin Bahar Rum na Iyali - rikicewar gado da aka maimaita na zazzaɓi da ƙonewa wanda yawanci yakan shafi rufin ciki, kirji, ko haɗin gwiwa
• Hairy cell leukemia - wani nau'in cutar kansa
• Cutar Hodgkin - ciwon daji na ƙwayar lymph
• Venwararrun cututtukan cututtukan yara - cututtukan zuciya da ke shafar yara
• Myeloma da yawa - nau'in cutar kansa ne
• Ciwon rashin lafiya - rukuni ne na yanayin da ke haifar da kumburi da kumburi ga gidajen abinci, idanu, da tsarin fitsari da al'aura)
• Rheumatoid amosanin gabbai
• Tsarin lupus erythematosus - cuta na rashin lafiyar jiki
• Tarin fuka

Kwayar cututtukan amyloidosis na sakandare sun dogara ne akan abin da jikin jikin yake da tasirin furotin. Wadannan adibas din suna lalata kyallen takarda. Wannan na iya haifar da bayyanar cututtuka ko alamun wannan rashin lafiyar, gami da:

• Zuban jini a cikin fata
• Gajiya
• Bugun zuciya mara tsari
• Umbarar hannu da ƙafa
• Rash
• Rashin numfashi
• Matsalar haɗiya
• Hannun kumbura ko ƙafafu
• Harshen kumbura
• Handarfin hannu mara ƙarfi
• Rage nauyi

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamunku.

Gwajin da za a iya yi sun hada da:

• Cikakken duban dan tayi (na iya nuna hanta ko kumbura)
• Biopsy ko fata mai ƙarkon fata (subcutaneous fat)
• Biopsy na dubura
• Biopsy na fata
• Kwayar halittar kasusuwa
• Gwajin jini, gami da creatinine da BUN
• Echocardiogram
• Lantarki (ECG)
• Gudun tafiyar da jijiyoyin jiki
• Fitsari

Ya kamata a kula da yanayin da ke haifar da amyloidosis. A wasu lokuta, an sanya magungunan colchicine ko magani na ilimin halittu (maganin da ke kula da garkuwar jiki).

Yaya mutum yake yi ya dogara da gabobin da abin ya shafa. Har ila yau ya dogara, ko cutar da ke haifar da ita za a iya shawo kanta. Idan cutar ta shafi zuciya da koda, zai iya haifar da gazawar sassan jiki da mutuwa.

Matsalar kiwon lafiya wanda zai iya haifar da amyloidosis na biyu ya haɗa da:

• Endocrine gazawar
• Ajiyar zuciya
• Rashin koda
• Rashin numfashi

Kira mai ba ku sabis idan kuna da alamun wannan yanayin. Wadannan suna da alamun bayyanar cututtuka waɗanda ke buƙatar saurin likita:

• Zuban jini
• Bugun zuciya mara tsari
• Numfashi
• Rashin numfashi
• Kumburi
• Rashin ƙarfi

Idan kana da wata cuta wacce aka santa tana ƙara haɗarinka ga wannan matsalar, ka tabbata ka samu magani. Wannan na iya taimakawa wajen hana amyloidosis.

Amyloidosis - tsarin na biyu; AA amyloidosis

• Amyloidosis na yatsunsu
• Amyloidosis na fuska
• Antibodies

Gertz MA. Amyloidosis. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 188.

Papa R, Lachmann HJ. Secondary, AA, Amyloidosis. Rheum Dis Clin Arewacin Am. 2018; 44 (4): 585-603. PMID: 30274625 www.ncbi.nlm.nih.gov/pubmed/30274625.