Cerebral amyloid angiopathy

Cerebral amyloid angiopathy (CAA) wani yanayi ne wanda sunadaran da ake kira amyloid suka hau kan bangon jijiyoyin cikin kwakwalwa. CAA na ƙara haɗarin bugun jini da ke faruwa sakamakon zub da jini da rashin hankali.

Mutanen da ke da CAA suna da ajiyar furotin amyloid a cikin bangon jijiyoyin jini a cikin kwakwalwa. Ba a saka furotin a ko'ina cikin jiki.

Babban mawuyacin haɗarin yana ƙaruwa da shekaru. CAA galibi ana ganin ta a cikin mutanen da suka girmi shekaru 55. Wani lokaci, ana yin ta ta cikin dangi.

CAA na iya haifar da zub da jini a cikin kwakwalwa. Zub da jini sau da yawa yakan faru a cikin ɓangarorin ƙwaƙwalwar, wanda ake kira bawo, ba wai zurfafan wuraren ba. Kwayar cuta na faruwa ne saboda zubar jini a cikin kwakwalwa yana cutar da ƙwayar kwakwalwa. Wasu mutane suna da matsalar ƙwaƙwalwar ajiya a hankali. Lokacin da aka yi hoton CT, akwai alamun cewa sun yi jini a kwakwalwa wanda watakila ba su ankara ba.

Idan jini ya yawaita, alamomin gaggawa suna faruwa kuma suyi kama da bugun jini. Wadannan alamun sun hada da:

• Bacci
• Ciwon kai (yawanci a wani sashi na kai)
• Canjin tsarin jijiyoyi wanda kan iya farawa kwatsam, gami da rikicewa, rashin hankali, hangen nesa biyu, rage gani, sauyin yanayi, matsalolin magana, rauni, ko nakasa
• Kamawa
• Stupor ko coma (da wuya)
• Amai

Idan zub da jini ba mai tsanani bane ko yaɗuwa, alamomi na iya haɗawa da:

• Ayyukan rikicewa
• Ciwon kai wanda yake zuwa ya tafi
• Rashin aikin tunani (lalatawa)
• Raunana ko wasu abubuwan ban mamaki waɗanda ke zuwa da tafiya, kuma sun haɗa da ƙananan yankuna
• Kamawa

CAA yana da wuyar ganewa ba tare da samfurin ƙwayar kwakwalwa ba. Wannan galibi ana yin sa ne bayan mutuwa ko lokacin da aka gudanar da biopsy na hanyoyin jini na kwakwalwa.

Gwajin jiki na iya zama na al'ada idan zubar jini ƙarami ne. Akwai wasu canje-canje na aikin kwakwalwa. Yana da mahimmanci ga likita yayi tambayoyi cikakke game da alamun cutar da tarihin lafiya. Alamar cutar da sakamakon gwajin jiki da duk wani gwajin hoto na iya sa likita ya yi zargin CAA.

Gwajin hotunan kan da za'a iya yi sun hada da:

• CT scan ko MRI scan don bincika zubar jini a cikin kwakwalwa
• Binciken MRA don bincika manyan zubar jini da kuma kawar da wasu abubuwan da ke haifar da zub da jini
• PET scan don bincika ajiyar amyloid a cikin kwakwalwa

Babu sanannen magani mai inganci. Makasudin magani shine don taimakawa bayyanar cututtuka. A wasu lokuta, ana buƙatar gyara don rauni ko damuwa. Wannan na iya haɗawa da aikin jiki, na sana'a, ko na magana.

Wani lokaci, ana amfani da magungunan da ke taimakawa inganta ƙwaƙwalwar, kamar waɗanda ke da cutar Alzheimer.

Zazzabi, wanda kuma ake kira maganin amyloid, ana iya maganin shi tare da ƙwayoyi masu kamawa.

Rashin lafiyar a hankali ya zama mafi muni.

Rarraba na CAA na iya haɗawa da:

• Rashin hankali
• Hydrocephalus (da wuya)
• Kamawa
• Maimaita lokutan zubar jini a cikin kwakwalwa

Jeka dakin gaggawa ko kira lambar gaggawa (kamar 911) idan batada motsi ko motsi, hangen nesa, ko magana.

Amyloidosis - kwakwalwa; CAA; Kwanfoliyya angiopathy

• Amyloidosis na yatsunsu
• Jijiyoyin kwakwalwa

Charidimou A, Boulouis G, Gurol ME, et al. Ra'ayoyi masu tasowa a cikin amyloid angiopathy na kwakwalwa. Brain. 2017; 140 (7): 1829-1850. PMID: 28334869 pubmed.ncbi.nlm.nih.gov/28334869/.

Greenberg SM, Charidimou A. Binciken asali na amyloid angiopathy: juyin halitta na ka'idojin Boston. Buguwa. 2018; 49 (2): 491-497. PMID: 29335334 pubmed.ncbi.nlm.nih.gov/29335334/.

Kase CS, Shoamanesh A. Zubar da jini tsakanin mahaifa. A cikin: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology a cikin Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016: babi na 66.