Hormone far don ciwon nono

Maganin Hormone don magance cutar sankarar mama yana amfani da kwayoyi ko jiyya zuwa ƙananan matakai ko toshe aikin homono na mace (estrogen da progesterone) a jikin mace. Wannan yana taimakawa rage saurin ciwan mama.

Maganin Hormone ya sa ba da yiwuwar dawowar kansa bayan an yi masa tiyata. Hakanan yana rage saurin ciwan sankarar mama wanda ya bazu zuwa sauran sassan jiki.

Hakanan za'a iya amfani da maganin Hormone don taimakawa rigakafin cutar kansa a cikin mata masu haɗarin cutar kansa.

Ya bambanta da maganin hormone don magance cututtukan menopause.

Hormone estrogen da progesterone suna sanya wasu cututtukan nono suyi girma. An kira su cututtukan nono masu saurin damuwa. Yawancin cututtukan nono suna da damuwa da hormones.

Ana samar da estrogen da progesterone a cikin ovaries da sauran kyallen takarda kamar su kitse da fata. Bayan gama al'ada, kwan mace ya daina samar da wadannan kwayoyin. Amma jiki yana ci gaba da yin ƙarami kaɗan.

Maganin Hormone yana aiki ne kawai akan cututtukan da ke da saurin haɗarin hormone. Don ganin idan maganin hormone na iya aiki, likitoci sun gwada samfurin ƙwayar cutar da aka cire yayin aikin tiyata don ganin idan kansar na iya zama mai damuwa da homonon.

Hormone far na iya aiki ta hanyoyi biyu:

• Ta hanyar toshe isrogen daga aiki akan kwayoyin cutar kansa
• Ta hanyar rage matakan estrogen a jikin mace

Wasu kwayoyi suna aiki ta hanyar toshe estrogen daga haifar da ƙwayoyin cutar kansa suyi girma.

Tamoxifen (Nolvadex) magani ne wanda ke hana estrogen daga gaya wa ƙwayoyin cutar kansa suyi girma. Yana da fa'idodi da yawa:

• Shan Tamoxifen na tsawon shekaru 5 bayan tiyatar kansar nono yana yanke damar kamuwa da cutar kansa da rabi. Wasu nazarin suna nuna cewa ɗaukar shi tsawon shekaru 10 na iya aiki mafi kyau.
• Yana rage haɗarin cewa ciwon daji zai yi girma a ɗayan nono.
• Yana jinkirta girma kuma yana rage ciwon daji wanda ya bazu.
• Yana rage barazanar kamuwa da cutar kansa a cikin matan da ke da haɗari.

Sauran magungunan da ke aiki iri ɗaya ana amfani da su don magance cutar kansa mai saurin gaske wacce ta bazu:

• Karenka (Fareston)
• Mai Kyau (Faslodex)

Wasu kwayoyi, waɗanda ake kira masu hana aromatase (AIs), suna dakatar da jiki daga yin estrogen a cikin kyallen takarda kamar kitse da fata. Amma, waɗannan kwayoyi basa aiki don sanya ƙwan ƙwai su daina yin estrogen. A saboda wannan dalili, ana amfani da su galibi don rage matakan estrogen a cikin matan da suka kasance ta hanyar jinin haila (postmenopausal). Ovwafinsu ba ya yin estrogen.

Matan da basu gama haihuwa ba zasu iya shan AI idan suma suna shan kwayoyi wadanda suke hana kwayayensu yin estrogen.

Masu hana aromatase sun hada da:

• Anastrozole (Arimidex)
• Letrozole (Femara)
• Kyakkyawan (Aromasin)

Irin wannan maganin yana aiki ne kawai a cikin matan da ba su taɓa haihuwa ba waɗanda ke da ƙwayayen kwai. Zai iya taimakawa wasu nau'ikan maganin hormone suyi aiki mafi kyau. Hakanan ana amfani dashi don magance ciwon daji wanda ya bazu.

Akwai hanyoyi guda uku don rage matakan estrogen daga ovaries:

• Yin aikin tiyata don cire ƙwarjin ƙwai
• Radiation ya lalata ovaries don haka ba sa aiki, wanda yake dindindin
• Magunguna kamar goserelin (Zoladex) da leuprolide (Lupron) waɗanda ke dakatar da kwayayen na ɗan lokaci daga yin estrogen

Duk wani daga cikin wadannan hanyoyin zai sanya mace cikin al'ada. Wannan yana haifar da bayyanar cututtuka na al'ada:

• Hasken walƙiya
• Zufar dare
• Rashin farji
• Yanayin motsi
• Bacin rai
• Rashin sha'awar jima'i

Sakamakon sakamako na maganin hormone ya dogara da magani. Illolin yau da kullun sun haɗa da walƙiya mai zafi, zufa na dare, da bushewar farji.

Wasu kwayoyi na iya haifar da ƙananan sakamako amma mafi mawuyacin sakamako, kamar:

• Tamoxifen. Ullewar jini, bugun jini, cututtukan ido, cututtukan endometrial da mahaifa, canjin yanayi, ɓacin rai, da rashin sha'awar jima'i.
• Masu hana aromatase. Babban cholesterol, bugun zuciya, asarar kashi, ciwon haɗin gwiwa, sauyin yanayi, da damuwa.
• Mai cikawa. Rashin cin abinci, jiri, amai, maƙarƙashiya, gudawa, ciwon ciki, rauni, da ciwo.

Yanke shawara kan maganin cutar sankara na sankarar mama na iya zama mai rikitarwa har ma da wahala. Nau'in magani da aka karɓa na iya dogara ne akan ko kun gama al'ada kafin a magance cutar kansa. Hakanan yana iya dogara da ko kuna son samun yara. Tattaunawa tare da mai kula da lafiyar ku game da zaɓuɓɓukan ku da fa'idodi da haɗarin kowane magani na iya taimaka muku yanke shawara mafi kyau a gare ku.

Hormonal far - ciwon nono; Maganin Hormone - kansar nono; Endocrine far; Ciwon daji mai saurin damuwa - far; ER tabbatacce - far; Masu hana aromatase - kansar nono

Tashar yanar gizon Cibiyar Cancer ta Amurka. Hormone far don ciwon nono. www.cancer.org/cancer/breast-cancer/treatment/hormone-therapy-for-breast-cancer.html. An sabunta Satumba 18, 2019. An shiga Nuwamba 11, 2019.

Henry NL, Shah PD, Haider I, Freer PE, Jagsi R, Sabel MS. Ciwon daji na nono. A cikin: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff na Clinical Oncology. Na 6 ed. Philadelphia, PA: Elsevier; 2020: babi na 88.

Yanar gizo Cibiyar Cancer ta Kasa. Hormone far don ciwon nono. www.cancer.gov/types/breast/breast-hormone-therapy-fact-sheet. An sabunta Fabrairu 14, 2017. An shiga Nuwamba 11, 2019.

Rugo HS, Rumble RB, Macrae E, et al. Endocrine far don mai karɓar hormone-tabbatacce ƙwayar ƙwayar nono: Americanungiyar Amurkan Amurka game da Gudanar da Lafiyar Oncology Clinical. J Clin Oncol. 2016; 34 (25): 3069-3103. PMID: 27217461 www.ncbi.nlm.nih.gov/pubmed/27217461.

• Ciwon nono