Musa

Mosaicism yanayi ne wanda ƙwayoyin da ke cikin mutum ɗaya suke da tsarin halittar jini daban. Wannan yanayin na iya shafar kowane nau'in kwayar halitta, gami da:

• Kwayoyin jini
• Kwai da kwayoyin maniyyi
• Kwayoyin fata

Mosaicism yana faruwa ne ta hanyar kuskure cikin rayayyun ƙwayoyin halitta farkon farkon haɓakar jaririn da ba a haifa ba. Misalan mosaicism sun haɗa da:

• Ciwon Mosaic Down
• Mosaic Klinefelter ciwo
• Ciwon Mosaic Turner

Kwayar cututtuka sun bambanta kuma suna da wuyar hango nesa. Kwayar cututtukan na iya zama ba mai tsanani ba idan kuna da ƙwayoyin cuta na al'ada da na al'ada.

Gwajin kwayar halitta na iya tantance mosaicism.

Da alama za a sake maimata gwaje-gwaje don tabbatar da sakamakon, da kuma taimakawa tantance iri da tsananin cutar.

Jiyya zai dogara ne da nau'in cuta da cutar. Kuna iya buƙatar ƙananan magani idan kawai wasu ƙwayoyin ba su da al'ada.

Yadda kuke yi ya dogara da gabobi da kyallen takarda (misali, kwakwalwa ko zuciya). Yana da wahala a iya hasashen tasirin samun layukan sel biyu daban a cikin mutum daya.

Gabaɗaya, mutanen da ke da yawan ƙwayoyin ƙwayoyin cuta na yau da kullun suna da ra'ayi iri ɗaya da mutanen da ke da nau'ikan cutar (waɗanda ke da ƙwayoyin cuta masu haɗari). Ana kiran nau'ikan nau'in ba-mosaic.

Mutanen da ke da ƙananan ƙwayoyin ƙwayoyin cuta na yau da kullun na iya zama mai sauƙi kaɗan. Wataƙila ba za su gano cewa suna da mosaicism ba har sai sun haifi ɗa wanda ke da nau'in cutar wanda ba mosaic ba. Wani lokaci yaron da aka haifa da sifar ba-mosaic ba zai rayu, amma yaron da aka haifa da mosaicism zai rayu.

Matsalolin sun dogara ne akan kwayoyin halitta da canjin halittar ya shafa.

Binciken asali na mosaicism na iya haifar da rikicewa da rashin tabbas. Mai ba da shawara kan kwayar halitta na iya taimaka amsa kowace tambaya game da ganewar asali da gwaji.

A halin yanzu babu wata sananniyar hanyar hana mosaicism.

Chromosomal mosaicism; Gonadal mosaicism

Driscoll DA, Simpson JL, Holzgreve W, Otaño L. Gwajin kwayoyin halitta da ganewar asali A cikin: Gabbe SG, Niebyl JR, Simpson JL, et al, eds. Obetetrics: Ciki da Ciki. 7th ed. Philadelphia, PA: Elsevier; 2017: babi na 10.

Nussbaum RL, McInnes RR, Willard HF. Binciken haihuwa da nunawa. A cikin: Nussbaum RL, McInnes RR, Willard HF, eds. Thompson da Thompson Genetics a Magunguna. 8th ed. Philadelphia, PA: Elsevier; 2016: babi na 17.