Autosomal koma baya

Motsa jiki na motsa jiki shine ɗayan hanyoyi da yawa waɗanda za'a iya ɗaukar cuta, cuta, ko cuta ta hanyar dangi.

Cutar rashin karfin jiki na nufin kwafi biyu na wata mahaukaciyar kwayar halitta dole ne su kasance don cutar ko halayen su haɓaka.

Gadon takamaiman cuta, yanayi, ko hali ya dogara da nau'in chromosome da abin ya shafa. Nau'o'in guda biyu sune chromosomes masu kwayar halitta da kuma jima'i. Hakanan ya dogara da ko ƙimar ta fi rinjaye ko ta koma baya.

Jin maye gurbi a cikin kwayar halitta akan daya daga cikin farkon chromosomes 22 da ba na jinsi ba na iya haifar da rashin lafiyar autosomal.

Kwayoyin halitta sun zo biyu-biyu. Jinsi daya a cikin kowane biyun ya fito daga mahaifiya, ɗayan kuma daga uba yake. Gado mai ragi yana nufin dukkanin kwayoyin halittar da ke cikin biyun dole ne su zama al'ada don haifar da cuta. Mutanen da ke da kwayar halitta guda ɗaya da ba ta da matsala a cikin biyun ana kiran su dako. Wadannan mutane galibi ba sa shafar yanayin. Koyaya, zasu iya ba da genea childrenansu ga asalinsu.

SAKAMAKON GADON TARI'A

Idan an haife ku ne ga iyayen da suke ɗauke da kwayar cutar ta autosomal recessive gene, kuna da damar 1 a cikin 4 na gadon kwayar cutar da ba ta dace ba daga iyayen biyu da kuma haifar da cutar. Kuna da damar samun kashi 50% (1 cikin 2) na gado daya na al'ada. Wannan zai sanya ku mai ɗauka.

A wasu kalmomin, ga yaron da aka haifa ga ma'aurata waɗanda ke ɗauke da kwayar halitta (amma ba su da alamun cuta), sakamakon da ake tsammani ga kowane ciki shi ne:

• Hannun 25% cewa an haifi yaron da kwayoyin al'ada biyu (na al'ada)
• Hanya ta 50% cewa an haifi yaron tare da ɗayan al'ada ɗaya da ɗayan mahaukaci (mai ɗauka, ba tare da cuta ba)
• Hannun 25% cewa an haife yaron tare da ƙwayoyin cuta guda biyu marasa haɗari (cikin haɗarin cutar)

Lura: Wadannan sakamakon ba yana nuna cewa tabbas yara zasu zama masu ɗauke da cutar ko kuma abin zai shafa su ba.

Halittar jini - autosomal recessive; Gado - autosomal koma baya

• Autosomal koma baya
• X-nasaba da recessive kwayoyin lahani
• Halittar jini

Feero WG, Zazove P, Chen F. Clinical genomics. A cikin: Rakel RE, Rakel DP, eds. Littafin karatun Magungunan Iyali. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 43.

Gregg AR, Kuller JA. Tsarin halittar mutum da tsarin gado. A cikin: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. Creasy da Resnik na Maganin Uwar-Gida: Ka'idoji da Ayyuka. 8th ed. Philadelphia, PA: Elsevier; 2019: babi na 1.

Korf BR. Ka'idojin gado. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 35.