HLA-B27 antigen

HLA-B27 gwajin jini ne don neman sunadarin da ake samu akan farjin ƙwayoyin jini. Ana kiran furotin din mutum leukocyte antigen B27 (HLA-B27).

Magungunan leukocyte antigens (HLAs) sunadarai ne waɗanda ke taimakawa tsarin garkuwar jiki ya faɗi bambanci tsakanin ƙwayoyin kansa da baƙin, abubuwa masu cutarwa. Anyi su ne daga umarni ta hanyar kwayoyin gado.

Ana bukatar samfurin jini. Mafi yawan lokuta, ana daga jini daga jijiya wacce take a cikin gwiwar hannu ko bayan hannu.

A mafi yawan lokuta, ba a buƙatar matakai na musamman don shirya don gwajin.

Lokacin da aka saka allurar don ɗiban jini, ƙila za ka ji zafi na matsakaici, ko ƙyalli kawai ko jin zafi. Bayan haka, ana iya samun wasu buguwa.

Mai ba da sabis na kiwon lafiya na iya yin odar wannan gwajin don taimakawa wajen gano dalilin ciwon haɗin gwiwa, taurin kai, ko kumburi. Za'a iya yin gwajin tare da wasu gwaje-gwajen, gami da:

• C-mai amsa furotin
• Erythrocyte sedimentation kudi (ESR)
• Rheumatoid factor
• X-haskoki

Ana amfani da gwajin HLA don dacewa da kayan da aka bayar tare da kayan jikin mutum wanda ke samun dashen wani ɓangare. Misali, ana iya yin sa yayin da mutum ya bukaci dashen koda ko dashen qashi.

Sakamakon al'ada (mara kyau) yana nufin HLA-B27 baya nan.

Gwajin tabbatacce yana nufin HLA-B27 yana nan. Yana ba da shawarar haɗari mafi girma fiye da matsakaici don haɓaka ko samun wasu rikice-rikice na autoimmune. Rashin lafiyar jiki wani yanayi ne da ke faruwa yayin da tsarin garkuwar jiki ya kuskure kai tsaye da lalata naman jikin mai lafiya.

Kyakkyawan sakamako na iya taimaka wa mai ba ku damar yin asalin cutar ta amosanin gabbai da ake kira spondyloarthritis. Irin wannan cututtukan arthritis ya hada da cututtuka masu zuwa:

• Ciwon mara
• Arthritis da ke da alaƙa da cututtukan Crohn ko ulcerative colitis
• Psoriatic arthritis (cututtukan zuciya da ke hade da psoriasis)
• Magungunan arthritis
• Sacroiliitis (kumburi na haɗin sacroiliac)
• Ciwon ciki

Idan kana da alamun cututtuka ko alamun spondyloarthritis, gwajin HLA-B27 mai kyau na iya taimakawa wajen tabbatar da ganewar asali. Koyaya, ana samun HLA-B27 a cikin wasu mutane na al'ada kuma ba koyaushe yake nufin kuna da cuta ba.

Haɗarin haɗari da ɗaukar jini ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Hematoma (jini yana taruwa a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

Kwayar cutar leukocyte antigen B27; Ankylosing spondylitis-HLA; Psoriatic amosanin gabbai-HLA; Maganin ƙwayar cuta-HLA

• Gwajin jini

Chernecky CC, Berger BJ. Human Leukocyte Antigen (HLA) B-27 - jini. A cikin: Chernecky CC, Berger BJ, eds. Gwajin Laboratory da hanyoyin bincike. Na 6 ed. St Louis, MO: Elsevier Saunders; 2013: 654-655.

Fagoaga KO. Antigen leukocyte antigen: babban hadadden tarihin hadewar mutum. A cikin: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Hanyoyin Laboratory. 23 ga ed. St Louis, MO: Elsevier; 2017: babi na 49.

Inman RD. Abubuwan da ke amfani da su. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 265.

McPherson RA, Massey HD. Bayani game da tsarin rigakafi da rikicewar rigakafi. A cikin: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Hanyoyin Laboratory. 23 ga ed. St Louis, MO: Elsevier; 2017: babi na 43.

Nuna JD. Spondyloarthritis. A cikin: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, 'Yan AJ, Weyand CM, eds. Immunology na Clinical: Ka'idoji da Ayyuka. 5th ed. Philadelphia, PA: Elsevier; 2019: babi na 57.