Pine na Maritime
Mawallafi:
Joan Hall
Ranar Halitta:
5 Fabrairu 2021
Sabuntawa:
20 Nuwamba 2024
Wadatacce
- Yiwuwar tasiri ga ...
- Zai yuwu bashi da tasiri ga ...
- Evidencearancin shaida don kimanta inganci don ...
- Kariya & Gargaɗi na Musamman:
Ana amfani da cirewar itacen pine na maritime don asma, inganta wasan motsa jiki, rashin wurare dabam dabam wanda zai iya haifar da ƙafafu zuwa kumburi (rashin ƙarancin jini ko CVI), da sauran yanayi da yawa, amma akwai iyakantattun shaidun kimiyya don tallafawa wasu daga waɗannan amfani.
Magunguna na Compwararren Bayanan Bayanai ƙimar tasiri bisa ga shaidar kimiyya bisa ga mizani mai zuwa: Inganci, Mai yuwuwa Mai Yiwuwa, Yiwuwar Tasiri, Yiwuwar Mara Inganci, Mai yiwuwa Mara Inganci, Mara Inganci, da suarancin Shaida don Rate.
Effectivenessimar tasiri don GASKIYAR MARITIME sune kamar haka:
Yiwuwar tasiri ga ...
- Asthma. Samun daidaitaccen tsantsar bawon hawan marine a kowace rana, tare da magungunan asma, da alama yana rage alamun cututtukan asma da kuma buƙatar masu shaƙa cikin yara da manya da asma. Lura cewa bai kamata a yi amfani da cirewar itacen pine na maritime a madadin maganin asma ba.
- Wasan motsa jiki. Matasa (masu shekaru 20-35) suna da alama za su iya motsa jiki a kan na'urar motsa jiki na dogon lokaci bayan shan daidaitaccen tsinken ɗanyen itacen marine a kowace rana na kimanin wata guda. Hakanan, horar da trainingan wasa don gwajin lafiyar jiki ko kuma triathlon kamar suna yin aiki mafi kyau a cikin gwaje-gwaje da gasa lokacin da suka ɗauki wannan ɗiban kowace rana tsawon makonni 8 yayin horo.
- Rashin yawo sosai wanda zai iya sa ƙafafu su kumbura (ƙarancin rashi ko CVI). Samun daidaitaccen tsantsar bawon bakin teku na bakin da alama rage ƙafafun ƙafafu da nauyi, gami da riƙe ruwa, a cikin mutanen da ke da matsalar yawo. Amfani da wannan tsamewar tare da matse matattara kuma ya bayyana yafi tasiri fiye da amfani da matattarar matsi shi kadai. Wasu mutane kuma suna amfani da kirjin kirjin kirjin don magance wannan yanayin, amma yin amfani da cirewar ɗanyen ƙwallan ruwan teku ya bayyana yafi tasiri.
Zai yuwu bashi da tasiri ga ...
- Babban cholesterol. Mafi yawan shaidu na nuna cewa daidaitaccen tsantsar bawon mara na teku ba ya rage "mummunan cholesterol" (low-density lipoprotein (LDL) cholesterol) a cikin mutanen da ke da babban cholesterol.
Evidencearancin shaida don kimanta inganci don ...
- Rage ƙwaƙwalwar ajiya da ƙwarewar tunani waɗanda ke faruwa daidai da shekaru. Yawancin bincike a cikin tsofaffi masu lafiya ba su sami ƙwaƙwalwar ajiya ko ƙwarewar tunani ba bayan sun sami daidaitaccen tsantsar bawon itacen pine.
- Eningarfafa jijiyoyin jini (atherosclerosis). Akwai wasu shaidu cewa shan daidaitaccen tsantsar bawon marine a sau uku kowace rana tsawon makonni 4 na iya taimakawa inganta wasu rikitarwa da ke tattare da taurin jijiyoyin jijiyoyin jiki.
- Rashin hankali-raunin rashin hankali (ADHD). Samun daidaitaccen tsantsar ruwan itacen pine na bakinka da alama ba zai taimaka alamun ADHD a cikin manya ba. Koyaya, shan shi da baki na tsawon wata ɗaya yana bayyana don inganta alamun cutar a cikin yara.
- Cutar da ba ta taɓa faruwa ba game da mawuyacin marura a cikin baki da sauran sassan jiki (Behcet syndrome). Bincike na farko ya nuna cewa shan ingantaccen tsinken ɗanyen tsire-tsire na marine yana inganta bayyanar cututtuka ga mutanen da ke da cutar Behcet.
- Prostara girman prostate (ciwon hawan jini ko BPH). Binciken farko da aka gudanar ya gano cewa shan ingantaccen tsinken bawon marainar teku yana da nasaba da ingantacciyar damar yin fitsari a cikin mutane masu cutar BPH.
- Memwaƙwalwar ajiya da ƙwarewar tunani (aikin fahimi). Bincike na farko ya gano cewa shan ingantaccen tsinken tsire-tsire na marine a baki yana inganta aikin tunani da ƙwaƙwalwar ajiya a cikin manya. Hakanan yana da alama ya ɗan inganta ƙirar gwajin a ɗaliban kwaleji.
- Rage ƙwaƙwalwar ajiya da ƙwarewar tunani a cikin tsofaffi waɗanda ya fi abin da ke al'ada ga shekarunsu. Bincike na farko ya nuna cewa shan ingantaccen tsinken ɗanyen tsire-tsire na marine yana inganta aikin tunani a cikin manya tare da rashin lahani.
- Ciwon sanyi. Bincike na farko ya gano cewa shan daidaitaccen tsantsar bawon marine a baki sau biyu a kowace rana farawa daga farkon mura yana rage yawan kwanaki da sanyi da. Hakanan yana iya rage adadin samfuran sanyi da ake buƙata don gudanar da alamomin.
- Haƙori. Bincike na farko ya nuna cewa cinga aƙalla gumma 6 na ɗanko tare da ƙarin abin cirewa daga bawon pine na maritime na tsawon kwanaki 14 yana rage zub da jini kuma yana hana ƙarin tabo.
- Ciwon suga. Shaidun farko sun nuna cewa shan ingantaccen tsinken tsire-tsire na marine a kowace rana tsawon makonni 3-12 yana rage sukarin jini sosai a cikin mutanen da ke fama da ciwon sukari.
- Ciwan ƙafa a cikin mutane masu ciwon sukari. Bincike na farko ya nuna cewa shan ruwan bawon marine a bakin da kuma shafa shi a fata yana taimakawa warkar da cututtukan kafa da ke da alaƙa da ciwon sukari.
- Wata cuta ta ƙananan jijiyoyin jini a cikin mutanen da ke fama da ciwon sukari (mai ciwon sukari microangiopathy). Bincike na farko ya nuna cewa shan ruwan itacen marine mai tsami cire sau uku a rana tsawon sati 4 yana inganta wurare dabam dabam da alamomin mutane da ciwon sukari.
- Matsalar hangen nesa a cikin mutanen da ke fama da ciwon sukari (mai ciwon sukari retinopathy). Samun daidaitaccen tsantsar bawon bakin marine a baki na tsawon watanni 2 da alama yana jinkirin ko hana ci gaba da ci gaba da kamuwa da cututtukan fuka da ke faruwa sakamakon ciwon sukari, atherosclerosis, ko wasu cututtuka. Hakanan yana inganta inganta gani.
- Bakin bushe. Bincike na farko ya nuna cewa shan tsantsar tsantsar ruwan bawon marine tare da yawun roba na inganta bushewar bakin da ta fi ta roba kawai.
- Cutar rashin lafiyar Erectile (ED). Bincike na farko ya nuna cewa daidaitaccen tsire-tsire na tsire-tsire na marine, wanda aka yi amfani da shi shi kaɗai ko a hade tare da L-arginine, na iya inganta aikin jima'i a cikin maza da ED. Da alama zai ɗauki watanni 3 na magani don ci gaba mai mahimmanci.
- Hay zazzabi. Wasu bincike sun nuna cewa shan ingantaccen tsinken tsire-tsire na ruwan marine kafin farkon lokacin alerji yana rage alamun rashin lafiyan cikin mutanen da ke fama da cutar birch.
- Basur. Binciken farko da aka gudanar ya nuna cewa shan wani daidaitaccen tsantsar ruwan bawon marine a baki, shi kadai ko a hade tare da wani maiko mai dauke da wannan maganin, yana inganta rayuwa da kuma alamun cutar basur. Sauran bincike sun nuna cewa shan wannan maganin a baki na iya inganta alamomin basur a cikin mata bayan sun haihu.
- Hawan jini. Wasu bincike sun nuna cewa shan ingantaccen tsinken bawon mara na iya rage saukar karfin jini. Amma sauran bincike bai nuna wani sakamako ba.
- Rashin lafiya na dogon lokaci na manyan hanji wanda ke haifar da ciwon ciki (ciwon mara na hanji ko IBS). Binciken farko da aka gudanar ya gano cewa shan wani daidaitaccen tsantsar ruwan kwalliyar marine na iya rage ciwon ciki, ciwon ciki, da amfani da magunguna ga mutanen da ke tare da IBS.
- Jirgin sama. Bincike na farko ya gano cewa shan daidaitaccen tsantsar bawon itacen marine, farawa kwanaki 2-3 kafin jirgin sama, na iya rage lokacin da alamun alamomin jet lag suke faruwa da kuma rage alamun alamun rashin ruwa.
- Matsanancin kafa. Akwai wasu shaidu da ke nuna cewa shan ingantaccen tsinken tsire-tsire na marine a baki zai iya rage raunin kafa.
- Ciwon kunne na ciki wanda aka yi alama da jiri, rashin ji, da ringi a kunne (cutar Meniere). Binciken farko ya nuna cewa shan daidaitaccen tsantsar ruwan itacen pine na teku na iya rage ringi a kunnuwa da sauran alamomi a cikin manya da cutar Meniere.
- Alamomin rashin al'ada. Binciken farko da aka gudanar ya gano cewa shan ingantaccen tsinken tsire-tsire na marine a bakin yana rage alamomin menopausal, gami da gajiya, ciwon kai, damuwa da damuwa, da walƙiya mai zafi.
- Ofungiyar alamun bayyanar cututtukan da ke ƙara haɗarin ciwon sukari, cututtukan zuciya, da bugun jini (cututtukan rayuwa). Bincike na farko ya nuna cewa shan tsantsar tsantsar bawon marine a baki sau uku a kullum na tsawon watanni 6 yana rage triglycerides, matakan sukarin jini, da hawan jini, kuma yana kara yawan kwalastaral mai yawan gaske ("mai kyau" ko HDL) a cikin mutane masu fama da ciwo mai illa .
- Kumburi (kumburi) da sores a cikin bakin (mucositis na baki). Yin amfani da maganin da ke dauke da daidaitaccen tsantsar bawon marine a cikin bakin har tsawon mako guda yana da alama zai taimaka wajan warkar da cututtukan bakin cikin yara da matasa masu shan magani na chemotherapy.
- Osteoarthritis. Akwai tabbatattun hujjoji game da tasirin itacen marine don maganin osteoarthritis. Samun daidaitaccen tsantsar bawon marine a bakin zai iya rage yawan alamun, amma da alama ba zai rage ciwo ko inganta ikon yin ayyukan yau da kullun ba. Binciken farko ya kuma gano cewa yin amfani da faci tare da daidaitaccen tsantsar ruwan itacen pine na teku na iya rage zafi ga mutanen da ke fama da cutar sanyin gwiwa.
- Cutar Parkinson. Bincike na farko ya gano cewa shan ingantaccen tsinken tsire-tsire na pine na teku tare da levodopa / carbidopa far na inganta rawar jiki da sauran alamomin jiki. Hakanan yana da alama inganta aikin tunani.
- Jin zafi ga mata masu ciki. Bincike na farko ya nuna cewa shan tsantsattsen ruwan itacen marine a baki kowace rana a cikin watanni 3 na ƙarshe na ɗaukar ciki yana rage ƙananan ciwon baya, haɗin gwiwa na hip, zafi na ƙugu, da kuma ciwo saboda jijiyoyin mara ko maraƙin maraƙi.
- Ciwon mara na ciki a cikin mata. Akwai hujja ta farko cewa shan daidaitaccen tsantsar bawon marine a bakin zai iya taimakawa rage radadin ciwon mara a cikin mata masu fama da cututtukan endometriosis ko ciwon mara mai tsanani.
- Scaly, fata mai kaushi (psoriasis). Binciken farko da aka gudanar ya gano cewa shan daidaitaccen tsantsar bawon bakin marine a baki zai iya rage girman alamun fata, inganta rayuwar, da rage amfani da kwayoyin sitirio a cikin mutane masu cutar psoriasis.
- Amsa mai zafi game da sanyi musamman a cikin yatsu da yatsun kafa (Ciwan Raynaud). Binciken farko ya gano cewa shan daidaitaccen tsantsar ruwan itacen pine na teku na iya inganta sanyi da zafi a yatsun cikin mutane masu wannan yanayin.
- Rashin tsoka mai shekaru (sarcopenia). Binciken farko da aka gudanar ya gano cewa shan ingantaccen tsinken tsire-tsire na marine a bakin yana inganta aikin tsoka a cikin tsofaffi tare da alamun raunin tsoka.
- Cutar da ke cikin jiki wanda glandon da ke samar da hawaye da miyau suka lalace (Sjogren syndrome). Binciken farko a cikin mutanen da ke fama da ciwo na Sjogren ya gano cewa shan ingantaccen ɗamarar bakin hauren marine a bakin yana rage alamun bushewar ido da bushewar baki. Hakanan yana iya rage buƙatar wasu magunguna.
- Cutar rashin karfin jiki wanda ke haifar da kumburi (systemic lupus erythematosus ko SLE). Bincike na farko ya nuna cewa shan daidaitaccen ruwan itacen pine na bakin yana rage alamun SLE a cikin wasu majiyyata.
- Ingara a kunnuwa (tinnitus). Bincike na farko ya nuna cewa shan daidaitaccen tsantsar bawon mara na marine yana rage ringi a kunnuwa.
- Magungunan varicose. Binciken farko da aka gudanar ya nuna cewa shan wani sikeli na ruwan itacen pine na maritime na iya rage ciwon kafa, kumburin kafa, da yawan jijiyoyin jijiyoyi da na jijiyoyin jijiyoyin mata bayan sun haihu.
- Jigilar jini da ke samuwa a cikin jijiyoyin jini (verom thromboembolism ko VTE). Specificaukar takamaiman takin jirgin ruwan marmarin shi kaɗai kafin da bayan doguwar tafiya ba ze hana hana daskarewar jini a cikin mutane masu haɗari ba. Amma zai iya rage haɗarin cututtukan post-thrombotic. Wannan yanayin na iya bunkasa cikin mutanen da suka riga sun sami daskarewar jini.
- Ajiyar zuciya.
- Ciwan tsoka.
- Matsaloli tare da aikin jima'i.
- Rigakafin bugun jini.
- Sauran yanayi.
Pine na maritime ya ƙunshi abubuwa waɗanda zasu inganta haɓakar jini. Hakanan yana iya haɓaka tsarin rigakafi, rage kumburi, hana cututtuka, kuma yana da tasirin antioxidant.
Lokacin shan ta bakin: Extractarancin tsantsar ruwan itacen pine na teku (Pycnogenol, Horphag Research) shine MALAM LAFIYA a cikin allurai na 50-450 MG kowace rana har zuwa shekara guda. Yana iya haifar da jiri, matsalolin ciki, ciwon kai, ciwon baki, da warin baki.
Lokacin amfani da fata: Extractarancin tsantsar ruwan itacen pine na teku (Pycnogenol, Horphag Research) shine MALAM LAFIYA a matsayin kirim har zuwa kwanaki 7 ko a matsayin foda har zuwa makonni 6.
Kariya & Gargaɗi na Musamman:
Ciki da shan nono: Bincike na farko ya nuna cewa daidaitaccen tsantsar bawon itacen marine (Pycnogenol, Horphag Research) shine MALAM LAFIYA lokacin amfani dashi a ƙarshen ciki. Koyaya, har sai an san ƙarin, ya kamata a yi amfani da shi a hankali ko kuma a guje shi daga mata masu ciki.Babu isasshen bayani gamsasshe game da amincin shan kayayyakin alatun maritime idan kuna shan nono. Kasance a gefen aminci ka guji amfani.
Yara: Extractarancin tsantsar ruwan itacen pine na teku (Pycnogenol, Horphag Research) shine MALAM LAFIYA lokacin shan ta bakin, gajere.
"Cutar cututtukan kansa" kamar su sclerosis da yawa (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), ko wasu yanayi: Pine na teku na iya haifar da tsarin garkuwar jiki ya zama mai aiki sosai, kuma wannan na iya ƙara alamun alamun cututtukan ƙwayoyin cuta. Idan kana da ɗayan waɗannan sharuɗɗan, zai fi kyau ka guji amfani da pine na maritime ..
Yanayin zubar jini: A ka'ida, yawan allunan ruwan marine na iya kara yiwuwar zub da jini a cikin mutane masu yanayin zubar jini.
Ciwon suga: A ka'ida, yawan allunan ruwan marine na iya rage yawan sukarin jini sosai ga mutanen da ke fama da ciwon sukari.
Ciwon hanta: A ka'ida, shan pine na maritime na iya tsananta aikin hanta ga mutanen da ke da ciwon hanta.
Tiyata: Pine na teku na iya jinkirta daskarewar jini kuma ya rage sukarin jini. Akwai wata damuwa cewa zai iya haifar da sukarin jini ya yi ƙasa sosai kuma ya ƙara damar jini yayin da bayan tiyata. Dakatar da amfani da pine na ruwa aƙalla makonni 2 kafin a shirya aikin tiyata.
- Matsakaici
- Yi hankali da wannan haɗin.
- Magunguna don ciwon sukari (Magungunan cututtukan siga)
- Pine na maritime na iya rage matakan sukarin jini. Ana amfani da magungunan ciwon suga don rage sukarin jini. Shan pine na teku tare da magungunan ciwon sukari na iya haifar da sukarin jininka ya yi ƙasa ƙwarai. Kula da yawan jinin ka sosai. Za a iya canza yawan adadin magungunan cutar sikari.
Wasu magungunan da ake amfani da su don ciwon suga sun haɗa da glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), da sauransu. Tsarin aikin ba shi da tabbas. - Magunguna waɗanda ke rage tsarin garkuwar jiki (Immunosuppressants)
- Pine na Maritime alama yana kara tsarin rigakafi. Ta hanyar kara karfin garkuwar jiki, itacen teku na iya rage tasirin magungunan da ke rage garkuwar jiki.
Wasu magungunan da ke rage garkuwar jiki sun hada da azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK50, ), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), da sauransu. - Magunguna waɗanda ke jinkirta daskarewar jini (Magungunan Anticoagulant / Antiplatelet)
- Pine na teku na iya jinkirta daskarewar jini. Shan pine na ruwa tare da magunguna wanda kuma jinkirin daskarewa na iya kara damar samun rauni da zubar jini.
Wasu magunguna da ke rage daskarewar jini sun hada da asfirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), da sauransu.
- Ganye da kari waɗanda zasu iya rage sukarin jini
- Pine na teku na iya rage matakan glucose na jini. Amfani da shi tare da wasu ganyayyaki ko kari waɗanda ke da tasiri iri ɗaya na iya haifar da matakan sukarin jini ya sauka ƙasa sosai. Wasu ganye da kari wadanda zasu iya rage suga cikin jini sun hada da alpha-lipoic acid, chromium, shedan's claw, fenugreek, tafarnuwa, guar gum, kirinjin doki, Panax ginseng, psyllium, Siberian ginseng, da sauransu.
- Ganye da kari wadanda zasu iya rage daskarewar jini
- Yin amfani da pine na teku tare da ganye wanda zai iya jinkirta daskarewar jini na iya ƙara haɗarin zubar jini a cikin wasu mutane. Wadannan ganyayyaki sun hada da Angelica, clove, danshen, tafarnuwa, ginger, ginkgo, Panax ginseng, da sauransu.
- Babu sanannun hulɗa da abinci.
MAGABATA
DA BAKI:
- Asthma: 1 MG na daidaitaccen tsire-tsire mai tsami na marine a kowane fam na nauyin jiki, har zuwa matsakaicin 200 MG / rana, an ba shi kashi biyu cikin kashi biyu na wata ɗaya. Hakanan, an yi amfani da MG 50 na wannan tsantsa sau biyu kowace rana tsawon watanni 6.
- Wasan motsa jiki: 100-200 MG an yi amfani da daidaitaccen tsire-tsire na tsire-tsire na marine a kowace rana tsawon watanni 1-2.
- Rashin yawo sosai wanda zai iya sa ƙafafu su kumbura (ƙarancin rashi ko CVI): An dauki 45-360 MG na daidaitaccen tsinkar ruwan itacen pine ana cirewa a kowace rana har zuwa kashi uku na kashi uku na makonni 3-12.
DA BAKI:
- Asthma: 1 MG na daidaitaccen tsire-tsire mai tsami na marine a kowane fam na nauyin jiki an ɗauka cikin kashi biyu kashi biyu na watanni 3 ta yara da matasa masu shekaru 6-18.
Don ƙarin koyo game da yadda aka rubuta wannan labarin, da fatan za a duba Magunguna na Compwararren Bayanan Bayanai hanya.
- Aldret RL, Bellar D. Wani Makafin Makaho biyu, Nazarin Tsallaka Gwaji don Nazarin Illolin Cire Jirgin Ruwa na Jirgin Ruwa a kan Ayyukan Motsa Jiki da Ciwon exan bayan Jiki, ressarfin Oxarfi, Ciwon Muscle, da Lalacewa. J Abincin Abincin. 2020; 17: 309-20. Duba m.
- Cesarone MR, Belcaro G, Agus GB, et al. Kullum venous insufficiency da venous microangiopathy: management tare da matsawa kuma Pycnogenol®. Minerva Cardioangiol. 2019; 67: 280-7. Duba m.
- Hu S, Hosoi M, Belcaro G, et al. Gudanar da laushi, cutar Raynaud na farko: kari tare da Pycnogenol®. Minerva Cardioangiol. 2019; 67: 392-8. Duba m.
- Cesarone MR, Belcaro G, Hosoi M, et al. Managementarin sarrafawa tare da Pycnogenol® a cikin cututtukan Parkinson don hana ƙarancin fahimta. J Neurosurg Sci. 2020; 64: 258-62. Duba m.
- Vinciguerra G, Belcaro G, Feragalli B, et al. PycnoRacer®, abin sha mai dacewa ciki har da Pycnogenol®, yana inganta murmurewa da horo a gwajin Cooper. Panminerva Med 2019; 61: 457-63. Duba m.
- Belcaro G, Cesarone MR, Cornelli U, et al. Xerostomia: rigakafi tare da karin Pycnogenol®: binciken matukin jirgi. Minerva Stomatol. 2019; 68: 303-7. Duba m.
- Cesarone MR, Belcaro G, Scipione C, et al. Rigakafin rashin bushewar farji a cikin mata masu lalata. Arin tare da Lady Prelox®. Minerva Ginecol. 2019; 71: 434-41. Duba m.
- Pourmasoumi M, Hadi A, Mohammadi H, Rouhani MH. Hanyoyin karin pycnogenol akan cutar hawan jini: Bincike na yau da kullun da zane-zane na gwaji na asibiti. Phytother Res. 2020; 34: 67-76. Duba m.
- Fogacci F, Tocci G, Sahebkar A, Presta V, Banach M, Cicero AFG. Tasirin Pycnogenol akan Matsalar Jinin: Nemo daga Bincike na Musamman na PRISMA da Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled, Clinical Studies. Angola. 2020; 71: 217-25. Duba m.
- Smetanka A, Stara V, Farsky I, Tonhajzerova I, Ondrejka I. carin Pycnogenol azaman ƙarin magani don magance matsalar lalatawar jima'i. Physiol Int 2019; 106: 59-69. Duba m.
- Luzzi R, Belcaro G, Hu S, et al. Inganci na haɓakar Pycnogenol a cikin saurin gafarar cutar Sjögren. Minerva Cardioangiol. 2018; 66: 543-546. Doi: 10.23736 / S0026-4725.18.04638-8. Duba m.
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