Nilotinib

Wadatacce

• Kafin shan nilotinib,
• Nilotinib na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:
• Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun alamun ko waɗanda aka lissafa a cikin Sashin GARGADI MAI MUHIMMAN, kira likitanku nan da nan:

Nilotinib na iya haifar da tsawan QT (wani zafin zuciya mara tsari wanda zai iya haifar da suma, rashin sani, kamuwa, ko mutuwa farat ɗaya). Faɗa wa likitanka idan kai ko kowa a cikin danginku suna da ko sun taɓa yin ciwo mai tsawo na QT (yanayin gado wanda mutum zai iya samun tsawan QT) ko kuma kun taɓa ko kuma kun taɓa samun ƙarancin matakan potassium ko magnesium a cikin jininka , bugun zuciya mara tsari, ko ciwon hanta. Faɗa wa likitan ku da likitan magunguna idan kuna shan amiodarone (Nexterone, Pacerone); antifungals irin su ketoconazole, itraconazole (Onmel, Sporanox), ko voriconazole (Vfend); chloroquine (Plaquenil); clarithromycin (Biaxin, a cikin Prevpac); pyarfafawa (Norpace); erythromycin (E.E.S., Eryc, PCE); wasu magunguna don kwayar cutar kanjamau (HIV) ko cutar rashin ƙarfi (AIDS) kamar atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, a Kaletra), da saquinavir (Invirase); haloperidol (Haldol); methadone (Dolophine, Methadose); moxifloxacin (Avelox); nefazodone; pimozide (Orap); procainamide; quinidine (a cikin Nuedexta); sotalol (Betapace, Betapace AF, wasu); telithromycin (Ketek); da thioridazine. Idan kun ji daya daga cikin wadannan alamun, ku daina shan nilotinib kuma ku kira likitanku nan da nan: azumi, bugawa, ko bugun zuciya mara tsari; suma; asarar hankali; ko kamuwa.

Kada ku ci kowane abinci aƙalla awanni 2 kafin shan nilotinib da kuma awa 1 bayan shan wannan magani.

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanku zai ba da umarnin wasu gwaje-gwaje, kamar su gwajin jini da na lantarki (EKGs, gwaje-gwajen da ke rikodin aikin lantarki na zuciya) kafin da yayin aikinku don tabbatar da cewa lafiya gare ku ku sha nilotinib.

Likitan ku ko likitan magunguna zai ba ku takaddun bayanan mai haƙuri (Jagoran Magunguna) lokacin da kuka fara magani tare da nilotinib kuma duk lokacin da kuka sake cika takardar sayan magani. Karanta bayanan a hankali kuma ka tambayi likitanka ko likitan magunguna idan kana da wasu tambayoyi. Hakanan zaka iya ziyarci gidan yanar gizon Abinci da Magunguna (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ko kuma gidan yanar gizon masana'anta don samun Jagoran Magunguna.

Yi magana da likitanka game da haɗarin shan nilotinib.

Ana amfani da Nilotinib don magance wasu nau'ikan cututtukan sankara na myeloid (CML; wani nau'in ciwon daji na farin ƙwayoyin jini) waɗanda kwanan nan suka gano suna da wannan yanayin a cikin manya da yara childrenan shekara 1 zuwa sama. Hakanan ana amfani dashi don magance wasu nau'ikan na CML wanda cutar ta kasa samun nasara tare da imatinib (Gleevec) ko kuma manya waɗanda basa iya shan imatinib. Ana amfani da Nilotinib don magance wasu nau'ikan na CML a cikin yara 'yan shekara 1 zuwa sama waɗanda cutar ba za a iya magance su cikin nasara ba tare da wasu hanyoyin kwantar da hanzarin tyrosine kinase. Nilotinib yana cikin aji na magungunan da ake kira kinase inhibitors. Yana aiki ta hanyar toshe aikin sunadarin da ba shi da kyau wanda ke nuna ƙwayoyin kansar su ninka. Wannan yana taimakawa wajen dakatarwa ko rage yaduwar kwayar cutar kansa.

Nilotinib ya zo a matsayin kwantena don ɗauka da baki. Yawanci ana shan shi ba tare da abinci sau biyu a rana ba. Ya kamata a sha Nilotinib a cikin komai a ciki, aƙalla awanni 2 kafin ko awa 1 bayan cin kowane abinci. Niauki nilotinib kusan lokaci ɗaya kowace rana. Oƙarin sararin allurai kimanin awanni 12. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Niauki nilotinib daidai yadda aka umurta. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Haɗa kawunansu duka tare da gilashin ruwa; kada ku rarraba, ku tauna, ko murkushe su. Idan baza ku iya haɗiye kafan ɗin gaba ɗaya ba, ku haɗa abin da ke cikin kwalin a cikin ƙaramin cokali ɗaya na applesauce. Swal haɗi hadin nan da nan (a cikin mintina 15.) Kada a adana cakuɗin don amfanin nan gaba.

Likitanka na iya rage yawan maganin ka na nilotinib ko kuma ya dakatar da jinyarka ya danganta da yadda maganin ke aiki a gare ka kuma idan ka fuskanci wani illa. Ci gaba da shan nilotinib koda kuwa kuna cikin koshin lafiya. Kada ka daina shan nilotinib ba tare da yin magana da likitanka ba.

Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan nilotinib,

• gaya wa likitan ku da likitan ku idan kun kasance masu rashin lafiyan nilotinib, duk wasu magunguna, ko kuma duk wani abin da ke cikin nilotinib capsules. Tambayi likitan ku ko bincika Littafin Magunguna don jerin abubuwan haɗin.
• gaya wa likitanka da likitan kantin ku wasu irin takaddun magani da magunguna marasa magani, bitamin, da kayan abinci mai gina jiki da kuke sha ko shirin sha.Tabbatar da ambaton magungunan da aka jera a cikin Sashin GARGADI MAI MUHIMMANCI da kowane ɗayan masu zuwa: wasu masu toshe hanyoyin karɓar rarar angiotensin kamar su irbesartan (Avapro, a Avalide) da losartan (Cozaar, a Hyzaar); maganin hana yaduwar jini ('' masu sanya jini '') kamar warfarin (Coumadin, Jantoven); aripiprazole (Abilify); wasu benzodiazepines kamar su alprazolam (Xanax), diazepam (Valium), midazolam, da triazolam (Halcion); buspirone (Buspar); wasu masu toshe tashoshin calcium kamar su amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Tiazac, wasu), felodipine, nicardipine (Cardene), nifedipine (Adalat, Procardia), nisoldipine (Sular), da verapamil (Calan, Verelan, wasu) ; wasu magungunan rage cholesterol (statins) gami da atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), da simvastatin (Zocor); chlorpheniramine (Chlor-Trimeton, sauran tari da kayayyakin sanyi); dexamethasone; dihydroergotamine (DHE 45, Migranal); ergotamine (a cikin Cafergot, a cikin Ergomar); fentanyl (Actiq, Duragesic, Subsys); flecainide (Tambocor); wasu magunguna don damuwa kamar amitriptyline, desipramine (Norpramin); duloxetine (Cymbalta); Imipramine (Tofranil); paroxetine (Brisdelle, Paxil, Pexeva); da venlafaxine (Effexor); wasu magungunan baka don ciwon suga kamar su glipizide (Glucotrol) da tolbutamide; wasu magunguna wadanda ke danne tsarin garkuwar jiki kamar su cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), da tacrolimus (Prograf); wasu magunguna don kamuwa kamar carbamazepine (Equetro, Tegretol, Teril), phenobarbital, da phenytoin (Dilantin, Phenytek); mexiletine; wasu cututtukan cututtukan ƙwayoyin cuta (NSAIDs) irin su celecoxib (Celebrex), diclofenac (Voltaren), ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), da piroxicam (Feldene); ondansetron (Zofran); propafenone (Rythmol); proton-pump inhibitors kamar su esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), da rabeprazole (AcipHex); quinine (Qualaquin); rifabutin (Mycobutin); rifampin (Rifadin); rifapentine (Priftin); risperidone (Risperdal); sildenafil (Viagra, Revatio); tamoxifen; testosterone (Androderm, Androgel, Striant, wasu); timolol; Gurin torsem; tramadol (Ultram, a cikin Ultracet); trazodone; da kuma vincristine. Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa. Sauran magunguna da yawa na iya ma'amala da nilotinib, don haka tabbatar da gaya wa likitanka game da duk magungunan da kuke sha, har ma waɗanda ba su bayyana a wannan jeri ba.
• idan kana shan antacids dauke da magnesium, aluminium (Maalox, Mylanta, Tums, wasu), ko simethicone, dauki antacid din sa'o'i 2 kafin ko kuma akalla awanni 2 bayan ka sha nilotinib.
• idan kuna shan magani don rashin narkewar abinci, ƙwannafi, ko ulce kamar cimetidine (Tagamet), famotidine (Pepcid, in Duexis), nizatidine (Axid), ko ranitidine (Zantac), ɗauki aƙalla awanni 10 kafin ko aƙalla 2 awoyi bayan kun sha nilotinib.
• gaya wa likitanka irin kayan ganyen da kake sha, musamman St. John’s wort.
• gaya wa likitanka idan an yi shanyewar jiki ko kuma tiyata don cire duka cikin (duka gastrectomy). Har ila yau, gaya wa likitanka idan kana da ko ka taɓa rage gudan jini zuwa ƙafafunka, duk matsalolin zuciya, matsalolin zub da jini, pancreatitis (kumburin ciki, glandan baya wanda ke samar da abubuwa don taimakawa narkewa), ko kowane yanayin da yana sanya wuya a gare ka ka narke lactose (madarar madara) ko sauran sugars.
• gaya wa likitanka idan kana da ciki ko ka shirya yin ciki. Bai kamata ku yi ciki ba yayin shan nilotinib. Ya kamata ku yi amfani da tasirin haihuwa mai amfani don hana ɗaukar ciki yayin maganin ku tare da nilotinib kuma tsawon kwanaki 14 bayan aikinku na ƙarshe. Yi magana da likitanka game da hanyoyin hana haihuwa waɗanda zaku iya amfani dasu yayin maganinku. Idan kun yi ciki yayin shan nilotinib, kira likitanku nan da nan. Nilotinib na iya cutar da ɗan tayi.
• gaya wa likitanka idan kana shan nono. Bai kamata ku shayar da nono ba yayin shan nilotinib kuma tsawon kwanaki 14 bayan aikinku na ƙarshe.
• idan kuna yin tiyata, gami da tiyatar hakori, gaya wa likita ko likitan hakori cewa kuna shan nilotinib.

Kada ku ci ɗan itacen inabi, ku sha ruwan inabi, ko ku ɗauki duk wani ƙarin abin da ke ƙunshe da ɓauren inabi yayin shan wannan magani.

Tsallake kashi da aka rasa kuma ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Nilotinib na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:

• kurji
• ƙaiƙayi
• tashin zuciya
• amai
• gudawa
• maƙarƙashiya
• ƙwannafi
• gas
• rasa ci
• ciwon kai
• jiri
• gajiya
• wahalar bacci ko bacci
• zufa na dare
• Ciwon tsoka
• baya, kashi, haɗin gwiwa, gaɓa, ko ciwon jiji
• asarar gashi
• bushewa ko jajayen fata
• suma, ƙonewa, ko ƙwanƙwasawa a hannu ko ƙafa

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun alamun ko waɗanda aka lissafa a cikin Sashin GARGADI MAI MUHIMMAN, kira likitanku nan da nan:

• zubar jini ko rauni
• jini a cikin fitsari
• na jini ko baƙi, kujerun tarry
• kwatsam ciwon kai, rikicewa, ko canje-canje a hangen nesa
• rashin gajiya ko rauni
• ciwon kirji ko rashin jin daɗi
• matsalolin tafiya ko magana
• rashin nutsuwa
• canji a cikin launin fata fata
• zafi ko jin sanyi a ƙafa
• ciwon ciki tare da tashin zuciya da amai
• zazzaɓi, sanyi, maƙogwaro, ci gaba tari da cunkoso, ko wasu alamun kamuwa da cuta
• kodadde fata
• karancin numfashi
• riba mai nauyi
• kumburin hannaye, idon sawu, ƙafa, ko fuska
• zafi ko rashin jin daɗi a yankin dama na sama
• rawaya fata da idanu
• fitsari mai duhu
• yin fitsari kasa da yadda aka saba

Nilotinib na iya haifar da yara su girma a hankali. Likitan ɗanka zai lura da haɓakar ɗanka a hankali yayin da ɗanka ke shan nilotinib. Yi magana da likitan ɗanka game da haɗarin bada wannan magani ga ɗanka.

Nilotinib na iya haifar da wasu sakamako masu illa. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye shi a zafin jiki na ɗaki kuma nesa da yawan zafin rana da danshi (ba cikin gidan wanka ba).

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani. Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Idan ya wuce gona da iri, kira layin taimakon guba a 1-800-222-1222. Hakanan ana samun bayanai akan layi akan https://www.poisonhelp.org/help. Idan wanda aka azabtar ya faɗi, ya kamu, fama da numfashi, ko ba za a iya farkawa ba, nan da nan kira sabis na gaggawa a 911.

Kwayar cututtukan ƙwayar ƙwayar cuta na iya haɗawa da:

• zazzabi, ciwon wuya, sanyi, ko wasu alamun kamuwa da cuta
• amai
• bacci

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

• Tasigna^®