Mawallafi: Clyde Lopez
Ranar Halitta: 24 Yuli 2021
Sabuntawa: 17 Nuwamba 2024
Anonim
Experience with Ceritinib for ALK+ NSCLC
Video: Experience with Ceritinib for ALK+ NSCLC

Wadatacce

Ana amfani da Ceritinib don magance wani nau'in ƙananan ƙwayoyin cuta na huhu (NSCLC) wanda ya bazu zuwa wasu sassan jiki. Ceritinib yana cikin aji na magungunan da ake kira masu hana motsi. Yana aiki ta hanyar toshe aikin wani furotin mara kyau wanda ke nuna ƙwayoyin kansar su ninka. Wannan yana taimakawa jinkiri ko dakatar da yaduwar kwayoyin cutar kansa.

Ceritinib ya zo a matsayin kwantena da kwamfutar hannu don ɗauka da baki. Yawanci ana ɗaukarsa da abinci sau ɗaya a rana. Cerauki ceritinib a kusan lokaci ɗaya kowace rana. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Cerauki ceritinib daidai yadda aka umurta. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Idan kayi amai bayan shan ceritinib, kar a sake shan wani maganin. Ci gaba da tsarin jadawalin yau da kullun.

Kwararka na iya rage yawan maganin ka na ceritinib, ya bi da kai tare da wasu magunguna, ko kuma ya gaya maka ka daina shan ceritinib na wani lokaci yayin maganin ka. Wannan zai dogara ne akan yadda magungunan ke aiki a gare ku da kuma duk wani illa da zaku iya fuskanta. Tabbatar da gaya wa likitanka yadda kake ji yayin jiyya tare da ceritinib.


Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan ceritinib,

  • gaya wa likitanka da likitan harka idan kana rashin lafiyan ceritinib, duk wasu magunguna, ko kuma duk wani sinadaran da ke cikin sinadarin cerinib capsules ko allunan. Tambayi likitan ku kan jerin kayan hadin.
  • gaya wa likitanka da likitan kantin ku wasu irin magunguna da magunguna marasa magani, bitamin, kayan abinci mai gina jiki, da kayan ganyen da kuke sha ko shirin dauka. Tabbatar da ambaci kowane ɗayan masu zuwa: amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); maganin hana yaduwar jini (‘masu kara jini)’ kamar warfarin (Coumadin, Jantoven); masu hana beta kamar atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Inderal) da sotalol (Betapace, Sorine, Sotylize); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); wasu magunguna don kwayar cutar kanjamau (HIV) ko ciwon rashin ƙarfi (AIDS) kamar efavirenz (Sustiva, a Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, a Kaletra), da saquinavir (Invirase); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin; clonidine (Catapres, Kapvay); corticosteroids; cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); pyarfafawa (Norpace); farfin kafa (Tikosyn); aikatapezil (Aricept); dronedarone (Multaq); escitalopram (Lexapro); fentanyl (Abstral, Actiq, Duragesic, Fentora, Biyan kuɗi); flecainide (Tambocor); fluconazole (Diflucan); haloperidol (Haldol); ibutilide (Corvert); itraconazole (Onmel, Sporanox, Tolsura); ketoconazole; levofloxacin; methadone (Dolophine, Methadose); moxifloxacin (Avelox); nefazodone; ondansetron (Zuplenz, Zofran); pentamidine (Pentam); sashin jiki; phenytoin (Dilantin, Phenytek); pimozide (Orap); pioglitazone (Actos, cikin Duetact, Oseni); procainamide; quinidine (a cikin Nuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, a cikin Rifater); sildenafil (Revatio); sirolimus (Rapamune); tacrolimus (Astagraf, Shirye-shirye); sabarini; vardenafil (Levitra, Staxyn); da verapamil (Calan, Covera, Isoptin, Verelan). Sauran magunguna da yawa na iya ma'amala tare da ceritinib, don haka tabbatar da gaya wa likitanka game da duk magungunan da kuke sha, har ma waɗanda ba su bayyana a wannan jeri ba. Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa.
  • gaya wa likitanka irin kayan ganyen da kake sha, musamman St. John’s Wort.
  • gaya wa likitanka idan kana da ko ka taba yin ciwon suga ko hawan jini, bugun zuciya, bugun zuciya ba daidai ba, tsawan QT (wani abu na rashin hankali da zai iya haifar da suma, rashin sani, kamuwa, ko mutuwa farat), ƙananan matakin na potassium ko magnesium a cikin jininka, pancreatitis (kumburin ciki), ko hanta hanta.
  • gaya wa likitanka idan kana da juna biyu, ko ka shirya yin ciki. Bai kamata ku yi ciki ba yayin shan ceritinib. Kuna buƙatar yin gwajin ciki kafin ku fara jiyya, kuma ya kamata ku yi amfani da hana haihuwa don hana ɗaukar ciki a yayin maganin ku kuma aƙalla watanni 6 bayan ƙaddararku ta ƙarshe. Idan kai namiji ne tare da mace wacce zata iya daukar ciki, ya kamata kayi amfani da maganin haihuwa don hana daukar ciki a yayin da kake jiyya kuma a kalla watanni 3 bayan aikinka na karshe. Yi magana da likitanka game da hanyoyin hana haihuwa waɗanda zasu yi aiki a gare ku. Ceritinib na iya cutar da jaririn da ke ciki. Idan kai ko abokin tarayyar ku sun yi ciki yayin jinyar ku tare da ceritinib, kira likitan ku nan da nan.
  • gaya wa likitanka idan kana shan nono. Kada ku shayar da nono yayin shan ceritinib kuma aƙalla makonni 2 bayan aikinku na ƙarshe.
  • idan kana yin tiyata, gami da tiyatar hakori, ka gaya wa likita ko likitan hakori cewa kana shan ceritinib.
  • ya kamata ku sani cewa zaku iya fuskantar hyperglycemia (ƙãra cikin jinin ku) yayin shan wannan magani. Faɗa wa likitanka kai tsaye idan kana da ɗayan waɗannan alamun yayin da kake shan ceritinib: ƙishirwa mai yawa, yawan fitsari, yunwa mai yawa, hangen nesa, ciwon kai, matsalar tunani ko maida hankali, numfashi yana kamshin 'ya'yan itace, ko gajiya.

Kada ku ci ɗan itacen inabi ko shan ruwan anab yayin shan wannan magani.


Doseauki kashi da aka rasa da zarar kun tuna shi. Koyaya, idan yana cikin awanni 12 na maganin ku na gaba, tsallake kashi da aka rasa kuma ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Ceritinib na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:

  • tashin zuciya
  • gudawa
  • amai
  • maƙarƙashiya
  • ciwon ciki
  • ƙwannafi
  • wahalar haɗiye
  • rasa ci
  • asarar nauyi
  • gajiya
  • kurji
  • ƙaiƙayi
  • canje-canje a hangen nesa
  • tsoka, kashi, hannu baya, ko ciwon kafa
  • ciwon kai

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun alamun ko waɗanda aka lissafa a cikin Sashin HANYA NA MUSAMMAN, kira likitan ku nan da nan:

  • zafi a hannun dama na sama na ciki
  • ƙwanƙwasawa ko jini
  • fitsari mai duhu
  • rawaya fata da idanu
  • rage yawan ci
  • cututtuka masu kama da mura
  • ƙaiƙayi
  • karancin numfashi
  • zazzaɓi, sanyi, maƙogwaro, ci gaba tari da cunkoso, ko wasu alamun kamuwa da cuta
  • ciwon kirji ko rashin jin daɗi
  • canje-canje a cikin bugun zuciya
  • bugun zuciya
  • jiri
  • rashin haske
  • suma
  • ciwo mai gudana wanda zai fara a cikin hagu na sama ko tsakiyar ciki amma zai iya yaɗuwa zuwa baya
  • kamuwa

Ceritinib na iya haifar da wasu sakamako masu illa. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.


Idan kun fuskanci mummunan sakamako, ku ko likitanku na iya aika rahoto ga shirin Abinci da Magunguna na Hukumar Kula da Abinci da Magunguna (FDA) na kan layi (http://www.fda.gov/Safety/MedWatch) ko ta waya ( 1-800-332-1088).

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye shi a zafin jiki na ɗaki kuma nesa da haske, yawan zafin rana da danshi (ba cikin gidan wanka ba).

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani. Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanku zai ba da umarnin wasu gwaje-gwajen gwaje-gwaje don bincika amsar jikinku ga ceritinib. Hakanan likitanku zai ba da umarnin gwajin gwaji kafin ku fara jiyya don gano ko za a iya magance kansar ku ta ceritinib.

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

  • Zykadia®
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