Lumacaftor da Ivacaftor

Wadatacce

• Kafin shan lumacaftor da ivacaftor,
• Lumacaftor da ivacaftor na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:
• Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, kira likitan ku nan da nan:
• Kwayar cututtukan ƙwayar ƙwayar cuta na iya haɗawa da:

Lumacaftor da ivacaftor ana amfani dasu don magance wasu nau'ikan cystic fibrosis (cutar da aka haifa wanda ke haifar da matsaloli tare da numfashi, narkewa, da haifuwa) a cikin manya da yara childrenan shekaru 2 zuwa sama. Lumacaftor yana cikin rukunin magunguna da ake kira masu gyara mai canzawa mai saurin cystic fibrosis (CFTR). Ivacaftor yana cikin ajin magunguna wanda ake kira mai iya daidaita yanayin sarrafawar cystic fibrosis (CFTR).Duk waɗannan magungunan suna aiki ta hanyar inganta aikin sunadarai a cikin jiki don rage haɓakar ƙurar gamji a cikin huhu da inganta sauran alamun cututtukan cystic fibrosis.

Haɗin lumacaftor da ivacaftor ya zo azaman kwamfutar hannu da kuma ɗakunan ajiya don ɗauka ta baki. Yawanci ana ɗauka tare da abinci mai mai sau biyu a rana, awowi 12 a tsakani. Lumauki lumacaftor da ivacaftor a kusan lokaci guda a kowace rana. Bi umarnin kan lakabin takardar sayan ku a hankali, kuma ku tambayi likitan ku ko likitan magunguna su bayyana duk wani ɓangaren da ba ku fahimta ba. Lumauki lumacaftor da ivacaftor daidai yadda aka umurta. Kar ka ɗauki ƙari ko ƙasa da shi ko ka sha shi sau da yawa fiye da yadda likitanka ya tsara.

Don shirya kashi na lumacaftor da kuma ivacaftor granules, haɗa dukkan fakitin granules a cikin cokali 1 (5 ml) na abinci mai laushi ko ruwa (sanyi ko a zafin jiki na ɗaki) kamar yogurt, applesauce, pudding, madara, ko ruwan 'ya'yan itace. Auki duka cakuran a cikin awa 1 na haɗa ƙwayoyin tare da abinci ko ruwa.

Lumauki lumacaftor da ivacaftor tare da abinci mai ƙwai kamar ƙwai, avocados, kwayoyi, man shanu, man gyada, cuku pizza, madara mai madara da sauran kayan madara iri iri kamar su cuku da yogurt mai cikakken kiɗa. Yi magana da likitanka game da sauran abinci mai maiko don ci tare da lumacaftor da ivacaftor.

Lumacaftor da ivacaftor suna sarrafa cystic fibrosis amma ba ya warkar da shi. Ci gaba da ɗaukar lumacaftor da ivacaftor ko da kun ji daɗi. Kada ka daina shan lumacaftor da ivacaftor ba tare da yin magana da likitanka ba.

Idan baka ɗauki lumacaftor da ivacaftor ba har tsawon kwanaki 7 ko fiye, kar a sake ɗaukar shi ba tare da yin magana da likitanka ba. Likitanku na iya buƙatar canza nauyin ku na wannan magani ko wasu magunguna da kuke sha.

Tambayi likitan ko likitan ku don kwafin bayanan masu sana'anta ga mai haƙuri.

Wannan magani za a iya wajabta shi don sauran amfani; nemi likita ko likitan magunguna don ƙarin bayani.

Kafin shan lumacaftor da ivacaftor,

• gaya wa likitan ku da likitan ku idan kun kasance masu rashin lafiyan lumacaftor da ivacaftor, duk wasu magunguna, ko duk wani sinadaran da ke cikin lumacaftor da allunan ivacaftor ko granules. Tambayi likitan ku kan jerin kayan hadin.
• gaya wa likitanka da likitan kantin ku irin magungunan da ba a ba da magani ba, bitamin, da kayan abinci mai gina jiki da kuke sha ko shirin sha. Tabbatar da ambaci ɗayan masu zuwa: wasu maganin rigakafi irin su itraconazole (Onmel, Sporanox), ketoconazole, posaconazole (Noxafil), da voriconazole (Vfend); wasu maganin rigakafi irin su clarithromycin (Biaxin, a Prevpac), erythromycin (E.E.S., Erythrocin, Eryped, wasu), rifabutin (Mycobutin) da rifampin (Rifadin, Rifamate, Rifater, Rimactane); wasu magunguna don ciwon suga kamar su chlorpropamide (Diabinese), glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, in Glucovance), repaglinide (Prandin), tolazamide da tolbutamide; digoxin (Lanoxin); ibuprofen (Advil, Motrin, a cikin Vicoprofen); wasu masu maganin rigakafi kamar cyclosporine (Gengraf, Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune) da tacrolimus (Astagraf, Prograf); midazolam; montelukast (Singulair); methylprednisolone (Medrol); prednisone (Rayos); wasu proton pump inhibitors (PPIs) kamar esomeprazole (Nexium, a Vimovo), lansoprazole (Prevacid, a Prevpac), da omeprazole (Prilosec, a Zegerid); ranitidine (Zantac); wasu magunguna don kamawa kamar carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, da phenytoin (Dilantin, Phenytek); wasu masu zaɓin maganin serotonin da aka zaɓa (SSRIs) kamar citalopram (Celexa), escitalopram (Lexapro), da sertraline (Zoloft); triazolam (Halcion); da warfarin (Coumadin, Jantoven). Likitanku na iya buƙatar canza ƙwayoyin magungunanku ko saka idanu a hankali don abubuwan illa. Sauran magunguna da yawa na iya yin ma'amala tare da lumacaftor da ivacaftor, don haka ka tabbata ka gaya wa likitanka duk magungunan da kake sha, har ma waɗanda ba su bayyana a wannan jeri ba.
• gaya wa likitanka irin kayan ganyen da kake sha, musamman St. John’s wort. Kila likitanku zai gaya muku kada ku ɗauki warin St. John yayin shan lumacaftor da ivacaftor.
• gaya wa likitanka idan kana da ko ka taba samun matsalar numfashi ko yanayi, dashen sassan jiki, ko hanta ko cutar koda.
• ya kamata ku sani cewa lumacaftor da ivacaftor na iya rage tasirin maganin hana daukar ciki na hormonal (kwayoyin hana haihuwa, faci, zobe, allura, implants, ko na'urorin intrauterine). Yi magana da likitanka game da wasu hanyoyin hana haihuwa waɗanda zasu yi aiki a gare ku yayin shan lumacaftor da ivacaftor.
• gaya wa likitanka idan kana da juna biyu, shirya yin ciki, ko kuma shayarwa. Idan kun kasance ciki yayin shan lumacaftor da ivacaftor, kira likitan ku.

Sai dai idan likitanku ya gaya muku in ba haka ba, ci gaba da abincinku na yau da kullun.

Idan ka tuna kashi da aka rasa a cikin awanni 6 na lokacin da aka tsara zaka sha shi, dauki kashi da aka rasa nan da nan. Koyaya, idan sama da awanni 6 sun shude tun daga lokacin da yawanci kuke ɗaukar lumacaftor da ivacaftor, ku tsallake adadin da aka rasa kuma ku ci gaba da tsarin jadawalin ku na yau da kullun. Kar a sha kashi biyu domin biyan wanda aka rasa.

Lumacaftor da ivacaftor na iya haifar da sakamako masu illa. Faɗa wa likitanka idan ɗayan waɗannan alamun sun yi tsanani ko kuma ba su tafi:

• karancin numfashi
• matsewar kirji ko ciwo
• matsalolin numfashi
• gudawa
• gas
• yawan gajiya
• kurji
• mara al'ada, rasa, nauyi ko raɗaɗin lokacin al'ada, musamman ga mata masu shan maganin hana haihuwa na hormonal
• hanci da hanci, atishawa, tari, ciwon wuya, ko alamomin mura
• ciwon wuya
• cunkoson hanci ko hanci
• ciwon kai

Wasu sakamako masu illa na iya zama mai tsanani. Idan kun sami ɗayan waɗannan alamun, kira likitan ku nan da nan:

• tashin zuciya
• amai
• rasa ci
• zafi a cikin ɓangaren dama na ciki
• fitsari mai duhu
• rikicewa
• rawaya fata ko idanu

Lumacaftor da ivacaftor na iya haifar da ciwon ido (gajimaren ido wanda zai iya haifar da matsalar hangen nesa) a cikin yara da matasa. Yara da matasa masu shan lumacaftor da ivacaftor ya kamata su ga likitan ido kafin da yayin ba su magani. Yi magana da likitan ɗanka game da haɗarin bada lumacaftor da ivacaftor ga ɗanka.

Lumacaftor da ivacaftor na iya haifar da wasu tasirin. Kira likitan ku idan kuna da wasu matsaloli na ban mamaki yayin shan wannan magani.

Idan kun fuskanci mummunan sakamako, ku ko likitanku na iya aika rahoto ga shirin Abinci da Magunguna na Hukumar Kula da Abinci da Magunguna (FDA) na kan layi (http://www.fda.gov/Safety/MedWatch) ko ta waya ( 1-800-332-1088).

Ajiye wannan maganin a cikin akwatin da ya shigo, a rufe sosai, kuma daga inda yara zasu isa. Ajiye shi a zafin jiki na ɗaki kuma nesa da yawan zafin rana da danshi (ba cikin gidan wanka ba).

Ya kamata a zubar da magunguna marasa magani ta hanyoyi na musamman don tabbatar da cewa dabbobin gida, yara, da sauran mutane ba za su iya cinye su ba. Koyaya, yakamata ku zubar da wannan maganin ta bayan gida. Madadin haka, hanya mafi kyau don zubar da maganinku shine ta hanyar shirin dawo da magani. Yi magana da likitan ka ko ka tuntuɓi sashen shara / sake amfani da datti na gida don koyon shirye-shiryen dawo da martabar ku a yankin ku. Dubi gidan yanar gizo na FDA mai lafiya na zubar da Magunguna (http://goo.gl/c4Rm4p) don ƙarin bayani idan ba ku da damar zuwa shirin karɓar kuɗi.

Yana da mahimmanci a kiyaye dukkan magunguna ba tare da gani ba kuma yara su isa kamar yadda kwantena da yawa (kamar masu ba da maganin kwaya na mako-mako da waɗanda suke don maganin ido, creams, faci, da kuma inhalers) ba sa jure yara kuma yara ƙanana na iya buɗe su cikin sauƙi. Don kare ƙananan yara daga guba, koyaushe kulle maɓallan aminci kuma nan da nan sanya magani a cikin amintaccen wuri - wanda ke sama da nesa kuma daga ganinsu kuma ya isa. http://www.upandaway.org

Idan ya wuce gona da iri, kira layin taimakon guba a 1-800-222-1222. Hakanan ana samun bayanai akan layi akan https://www.poisonhelp.org/help. Idan wanda aka azabtar ya faɗi, ya kamu, fama da numfashi, ko ba za a iya farkawa ba, nan da nan kira sabis na gaggawa a 911.

Kwayar cututtukan ƙwayar ƙwayar cuta na iya haɗawa da:

• ciwon kai
• kurji

Kiyaye duk alƙawarin tare da likitanku da dakin gwaje-gwaje. Likitanku zai ba da umarnin gwajin gwaji kafin ku fara jiyya don ganin ko za a iya magance yanayinku tare da lumacaftor da ivacaftor kamar yadda ya kamata a yi amfani da shi kawai ga mutanen da ke da wani irin yanayin halittar. Kwararka zai ba da umarnin gwajin ido da wasu gwaje-gwajen gwaje-gwaje a gabanin da yayin jiyya don bincika martanin jikinka ga lumacaftor da ivacaftor. Ya kamata a binciki karfin jininka a kai a kai yayin shan wannan magani.

Kar ka bari wani ya sha maganin ka. Tambayi likitan ku duk wata tambaya da kuke da ita game da sake shigar da takardar sayan ku.

Yana da mahimmanci a gare ku da ku kiyaye jerin rubutattun dukkanin rubutattun magunguna da kuma wadanda ba a rubuta su ba (kan-kan-kan-kan) magungunan da kuke sha, har ma da wasu kayayyaki kamar su bitamin, ma'adanai, ko wasu kayan abincin da ake ci. Ya kamata ku kawo wannan jeren tare da ku duk lokacin da kuka ziyarci likita ko kuma idan an shigar da ku a asibiti. Hakanan mahimman bayanai ne don ɗauka tare da yanayin gaggawa.

• Orkambi^®