Jagoran ku ga Anti-Androgens

Wadatacce

• Yaya ake amfani da su?
• Na mata
• Don mata masu canza jinsi da mutane
• Na maza
• Menene wasu gama gari?
• Flutamide
• Spironolactone
• Cyproterone
• Menene illar?
• Layin kasa

Menene anti-androgens?

Androgens sune hormones waɗanda ke tsara ci gaban halayen jima'i. Yawanci, mutanen da aka haifa da halayen jima'i na maza suna da matakan androgens masu yawa. Mutanen da aka haifa da halayen mata suna da ƙananan matakan androgens. Madadin haka, suna da matakan estrogens masu yawa.

Magungunan anti-androgen suna aiki ta hanyar toshe tasirin androgens, kamar su testosterone. Suna yin wannan ta hanyar ɗaure ga sunadaran da ake kira androgen receptors. Suna ɗaure ga waɗannan masu karɓar don inrogens ba za su iya ba.

Akwai nau'ikan anti-androgens da yawa. Yawancin lokaci ana shan su tare da wasu magunguna ko yayin wasu hanyoyin tiyata.

Yaya ake amfani da su?

Anti-androgens suna da amfani da yawa, daga sarrafa kansar prostate zuwa rage gashin fuska mara buƙata.

Na mata

Duk mata suna haifar da amountan ƙaramin asrogens. Koyaya, wasu mata suna samarwa fiye da wasu.

Misali, matan da ke fama da cutar yoyon fitsari (PCOS) suna da matakan asrogen mai girma. Wannan na iya haifar da yawan ci gaban gashi, kuraje, da kuma matsalar rawan ƙwai. Anti-androgens na iya taimakawa rage waɗannan alamun a cikin mata masu cutar PCOS.

Sauran yanayin da ke haifar da babban asrogens a cikin mata sun haɗa da:

• adrenal hyperplasia
• kumburin ovarian
• adrenal gland marurai

Anti-androgens na iya taimakawa wajen gudanar da waɗannan sharuɗɗan da hana rikice-rikicen da ke tattare da matakan asrogen mai girma a cikin mata. Wadannan rikitarwa sun haɗa da:

• ciwon sukari
• babban cholesterol
• hawan jini
• ciwon zuciya

Don mata masu canza jinsi da mutane

Ga mutanen da ke cikin canji, anti-androgens na iya taimakawa wajen toshe wasu daga tasirin tasirin na testosterone. Zasu iya rage wasu halayen halayen maza, kamar:

• kwalliyar maza
• girman gashin fuska
• gyaran safe

Anti-androgens sun fi tasiri ga matan transgender lokacin da aka ɗauke su da estrogen, babban hormone na mata. Baya ga haifar da ci gaban halayen mata na zahiri, kamar su mama, estrogen kuma a kaikaice yana rage matakan testosterone. Yin amfani da anti-androgens tare da estrogen na iya taimakawa duka biyun don kawar da halaye na maza da haɓaka na mata.

Ga mutanen da suka nuna cewa rashin haihuwa ne, shan anti-androgens shi kaɗai na iya taimakawa rage halayen namiji.

Na maza

Androgens yana kara girman kwayar cutar kansa a cikin prostate. Rage matakan androgen, ko hana androgens isa cikin kwayoyin cutar kansa, na iya taimakawa sannu a hankali cutar kansa. Hakanan yana iya ƙyamar ciwace-ciwacen da suka kasance.

A farkon matakansa, kwayoyin cutar kansar mafitsara sun dogara da androgens don ciyar da haɓakar su. Anti-androgens suna aiki ta hanyar toshewa androgens daga ɗaure wa masu karɓar nau'o'in inrogene a cikin ƙwayoyin sankara ta prostate. Wannan yana lalata kwayoyin cutar kansa na androgens da suke buƙata don girma.

Duk da haka, anti-androgens ba su daina samar da androgen. Sau da yawa ana amfani da su a hade tare da wasu jiyya, kamar su aikin tiyata ko jefa sinadarai. Wadannan haɗuwa ana kiran su:

• hade haɗin inrogen
• cikakken toshewar inrogen
• jimlar toshewar isrogen

Menene wasu gama gari?

Akwai anti-androgens da yawa da ake dasu, kowannensu yana da amfani daban daban. Anan ga wasu shahararrun mutane.

Flutamide

Flutamide wani nau'in anti-androgen ne wanda ake amfani dashi tare da wasu magunguna don magance wasu nau'ikan cututtukan prostate. Flutamide yana ɗaure ga masu karɓar nau'o'in inrogene a cikin ƙwayoyin cutar kanjamau, wanda ke toshe androgens daga ɗaure wa masu karɓa. Wannan yana hana androgens daga ƙarfafa haɓakar ƙwayar ƙwayar ƙwayar ƙwayar cuta.

Spironolactone

Spironolactone (Aldactone) wani nau'in anti-androgen ne wanda ake amfani dashi don magance cututtukan fata na hormonal da yawan gashin jiki. Mutane masu sauyawa na iya ɗauka don rage halayen namiji. Kodayake akwai wata karamar shaidar da za ta tallafawa amfani da ita, kuma sanya ta don yanayin kwalliyar mata.

Cyproterone

Cyproterone shine ɗayan farkon anti-androgens. Yana tare da wasu magunguna don magance mata da PCOS. Hakanan an nuna shi zuwa matakan testosterone da kuma samar da mai mai haifar da ƙuraje.

Hakanan za'a iya amfani dashi don rage halaye na maza a cikin matan transgender. Koyaya, saboda illolinsa, gabaɗaya ba a fifita shi ba.

Menene illar?

Anti-androgens na iya haifar da kewayon sakamako masu illa, gwargwadon sashi da nau'in da kuka sha.

Wasu tasiri masu illa sun haɗa da:

• karancin jima'i
• ƙara haɗarin baƙin ciki
• haɓaka hanta enzymes
• rage gashin fuska da na jiki
• mafi haɗarin lalacewar haihuwa idan aka ɗauka yayin ɗaukar ciki
• ciwon hanta
• hanta rauni
• rashin karfin erectile
• gudawa
• taushin nono
• walƙiya mai zafi
• rashin al'ada
• kumburin fata
• anti-androgen juriya, ma'ana magani ya daina aiki

Kwararka na iya taimaka maka zaɓi anti-androgen wanda ya fi dacewa da buƙatunka kuma ya zo tare da ƙananan sakamako masu illa.

Layin kasa

Anti-androgens suna da amfani da yawa ga maza, mata, da mutane a cikin canjin yanayin jinsi, duka nasu kuma tare da wasu magunguna da magunguna. Koyaya, anti-androgens magunguna ne masu ƙarfi waɗanda zasu iya haifar da wasu lahani masu illa. Yi aiki tare da likitanka don auna fa'idodi da cutarwa na shan anti-androgens.