Eculizumab - Menene don haka

Wadatacce

• Menene don
• Farashi
• Yadda ake amfani da shi
• Babban sakamako masu illa
• Lokacin da baza ayi amfani dashi ba

Eculizumab wani maganin rigakafi ne na monoclonal, wanda aka siyar dashi ta kasuwanci da sunan Soliris. Yana inganta amsawar mai kumburi kuma yana rage ikon jiki don kai farmaki kan ƙwayoyin jininta, ana nuna shi mafi yawa don yaƙi da wata cuta mai saurin gaske da ake kira hemoglobinuria paroxysmal nocturnal.

Menene don

Maganin Soliris an nuna shi don maganin cutar jini da ake kira paroxysmal nocturnal hemoglobinuria; wata cuta ta jini da koda da ake kira atypical hemolytic uremic syndrome, inda za a iya samun thrombocytopenia da karancin jini, baya ga daskarewar jini, gajiya da rashin aiki na gabobi daban-daban, ana kuma nuna su don kula da cutar Myasthenia gravis.

Farashi

A Brazil, Anvisa ta amince da wannan magani, kuma SUS ta samar da shi ta hanyar kara, ba a sayar da shi a shagunan sayar da magani.

Yadda ake amfani da shi

Dole ne a yi amfani da wannan maganin azaman allura a asibiti. Gabaɗaya, ana yin magani tare da ɗigon ruwa a cikin jijiya, na kimanin minti 45, sau ɗaya a mako, na tsawon makonni 5, har sai an yi gyara ga matakin da za a yi amfani da shi kowane kwana 15.

Babban sakamako masu illa

Eculizumab yana da haƙuri sosai, mafi yawanci shine farkon ciwon kai. Koyaya, illoli kamar su thrombocytopenia, rage jajayen jini, zafi a ciki, maƙarƙashiya, gudawa, rashin narkewar abinci, tashin zuciya, ciwon kirji, sanyi, zazzaɓi, kumburi, gajiya, rauni, herpes, gastroenteritis, kumburi kuma na iya faruwa. , amosanin gabbai, ciwon huhu, ciwon sankarau na meningococcal, ciwon tsoka, ciwon baya, ciwon wuya, jiri, rage dandano, kunbura a jiki, tsagaitawar kai tsaye, tari, ciwon makogwaro, toshewar hanci, jiki mai kumburi, faduwa daga gashi, busasshiyar fata.

Lokacin da baza ayi amfani dashi ba

Kada ayi amfani da Soliris a cikin mutanen da ke rashin lafiyan kowane irin ɓangaren maganin, kuma idan har kamuwa da cutar Neisseria meningitidis da ba a warware ba, mutanen da ba su sami rigakafin cutar sankarau ba.

Wannan magani yakamata ayi amfani dashi a cikin ciki, karkashin shawarar likita kuma idan ya zama dole, saboda yana wucewa ta mahaifa kuma yana iya tsoma baki game da zagawar jinin jariri. Hakanan ba a nuna amfani da shi yayin shayarwa ba, don haka idan mace tana shayarwa, to ta tsaya na tsawon watanni 5 bayan amfani da wannan magani.