Cutar Ehlers-Danlos: Menene Ita Kuma Yaya ake Kula da ita?

Wadatacce

• Me ke haifar da EDS?
• Menene alamun cutar EDS?
• Kwayar cututtukan EDS na gargajiya
• Kwayar cututtukan hypermobile EDS (hEDS)
• Kwayar cututtukan EDS
• Ta yaya ake bincika EDS?
• Yaya ake kula da EDS?
• Matsalolin da ke iya faruwa na EDS
• Outlook

Menene cutar Ehlers-Danlos?

Ciwon Ehlers-Danlos (EDS) wani yanayi ne na gado wanda ke shafar ƙwayoyin haɗin jikin mutum. Kayan haɗin kai suna da alhakin tallafawa da tsara fata, jijiyoyin jini, ƙasusuwa, da gabobin. Ya ƙunshi ƙwayoyin halitta, kayan zare, da furotin da ake kira collagen. Wani rukuni na rikicewar kwayar halitta yana haifar da ciwo na Ehlers-Danlos, wanda ke haifar da lahani a cikin samar da haɗin collagen.

Kwanan nan, manyan nau'ikan nau'ikan ciwo na Ehlers-Danlos guda 13 sun kasance an yiwa ruɗi. Wadannan sun hada da:

• na gargajiya
• gargajiya-kamar
• bugun zuciya-valvular
• jijiyoyin jini
• hypermobile
• arthrochalasia
• dermatosparaxis
• kyphoscoliotic
• ƙwanƙwasa ƙwanji
• fandararraza
• musculocontractural
• myopathic
• lokaci-lokaci

Kowane nau'i na EDS yana shafar wurare daban-daban na jiki. Koyaya, duk nau'ikan EDS suna da abu ɗaya ɗaya: hypermobility. Hypermobility wani yanki ne mai girman ban mamaki na motsi a cikin gidajen.

A cewar National Library of Medicine's Genetics Home Reference, EDS yana shafar 1 a cikin mutane 5,000 a duniya. Hypermobility da nau'ikan nau'ikan cututtukan Ehlers-Danlos sune mafi yawancin. Sauran nau'ikan suna da wuya. Misali, dermatosparaxis ya shafi yara kusan 12 a duniya.

Me ke haifar da EDS?

A mafi yawan lokuta EDS yanayin gado ne. 'Yan tsirarun shari'o'in ba a gado. Wannan yana nufin cewa suna faruwa ne ta hanyar maye gurbi. Laifi a cikin kwayoyin halitta ya raunana tsari da samuwar collagen.

Dukkanin kwayoyin halittar da aka jera a kasa suna bada umarni kan yadda ake hada collagen, banda ADAMTS2. Wannan kwayar halitta tana ba da umarni don yin sunadaran da suke aiki tare da collagen. Kwayoyin halittar da zasu iya haifar da EDS, yayin da ba cikakken lissafi bane, sun hada da:

• ADAMTS2
• COL1A1
• COL1A2
• COL3A1
• COL5A1
• COL6A2
• FATA 1
• TNXB

Menene alamun cutar EDS?

Iyaye wasu lokuta masu ɗaukar shiru ne na lalatattun kwayoyin halittar da ke haifar da EDS. Wannan yana nufin iyaye na iya samun alamun bayyanar yanayin. Kuma basu sani ba suna dako ne na lalatacciyar kwayar halitta. Wasu lokuta, dalilin kwayar halitta shine rinjaye kuma yana iya haifar da bayyanar cututtuka.

Kwayar cututtukan EDS na gargajiya

• sako-sako da gidajen abinci
• na roba mai saurin canzawa, fata mai laushi
• fata mai lalacewa
• fatar da ke saurin laushi
• m fata folds a kan idanu
• ciwon tsoka
• gajiyawar tsoka
• ci gaba mara kyau akan yankunan matsa lamba, kamar gwiwar hannu da gwiwoyi
• matsalolin bugun zuciya

Kwayar cututtukan hypermobile EDS (hEDS)

• sako-sako da gidajen abinci
• sauki rauni
• ciwon tsoka
• gajiyawar tsoka
• cututtukan haɗin gwiwa na ci gaba
• osteoarthritis da wuri
• ciwo na kullum
• matsalolin bugun zuciya

Kwayar cututtukan EDS

• magudanan jini
• siraran fata
• m fata
• siririn hanci
• idanun fitattu
• bakin lebe
• kunci kunci
• karamin chin
• huhu ya fadi
• matsalolin bugun zuciya

Ta yaya ake bincika EDS?

Doctors na iya amfani da jerin gwaje-gwaje don tantance cutar ta EDS (banda ta HEDS), ko kuma cire wasu halaye makamantan su. Wadannan gwaje-gwajen sun hada da gwaje-gwajen kwayoyin halitta, nazarin halittun fata, da kuma echocardiogram. Echocardiogram yana amfani da raƙuman sauti don ƙirƙirar hotuna masu motsi na zuciya. Wannan zai nuna wa likita idan akwai wasu abubuwan rashin lafiya da ke wurin.

Ana ɗauke samfurin jini daga hannunka a gwada maye gurbi a wasu ƙwayoyin halitta. Ana amfani da biopsy na fata don bincika alamun rashin daidaito a cikin samar da haɗin collagen. Wannan ya hada da cire karamin samfurin fata da duba shi ta hanyar madubin hangen nesa.

Har ila yau, gwajin DNA na iya tabbatarwa idan kwayar halitta mai nakasa tana cikin amfrayo. Ana yin wannan nau'ikan gwajin ne yayin da kwayayen mace suka hadu a waje da jikinta (in vitro fertilization).

Yaya ake kula da EDS?

Zaɓuɓɓukan magani na yanzu don EDS sun haɗa da:

• maganin jiki (da ake amfani dashi don gyara waɗanda suke tare da haɗin gwiwa da rashin narkar tsoka)
• tiyata don gyara wuraren haɗuwa
• magunguna don rage zafi

Arin zaɓuɓɓukan magani na iya zama ya dogara da yawan ciwon da kuke ciki ko wasu ƙarin alamun alamun.

Hakanan zaka iya ɗaukar waɗannan matakan don hana raunin da kare haɗin gwiwa:

• Guji wasannin tuntuba.
• Guji ɗaga nauyi.
• Yi amfani da hasken rana don kare fata.
• Guji sabulai masu kauri da zasu iya shafar fata ko haifar da rashin lafiyan jiki.
• Yi amfani da na'urori masu tallafi don rage girman matsi akan gidajenku.

Hakanan, idan ɗanka yana da EDS, bi waɗannan matakan don hana rauni da kiyaye haɗin haɗin gwiwa. Bugu da kari, sanya isassun padding a kan yaro kafin su hau keke ko suna koyon tafiya.

Matsalolin da ke iya faruwa na EDS

Rarraba na EDS na iya haɗawa da:

• ciwon haɗin gwiwa na kullum
• rabuwar kai
• farkon farawa amosanin gabbai
• jinkirin warkar da raunuka, wanda ke haifar da manyan tabo
• raunukan tiyata waɗanda ke da wahalar warkewa

Outlook

Idan kuna tsammanin kuna da EDS bisa ga alamun bayyanar da kuke fuskanta, to shigo da likita ne. Zasu iya tantance ku da wasu 'yan gwaje-gwaje ko kuma yanke hukuncin wasu halaye makamantan su.

Idan an gano ku tare da yanayin, likitanku zai yi aiki tare da ku don samar da tsarin kulawa. Bugu da ƙari, akwai matakai da yawa da zaku iya ɗauka don hana rauni.