Ficarancin Yanayi na VII

Wadatacce

• Wace rawa factor VII ke takawa a dunkulewar jini na al'ada?
• 1. Maganin Vasoconstriction
• 2. Samuwar faranti
• 3. Samuwar filastin fibrin
• 4. Raunin rauni da lalata fulogin fibrin
• Menene ke haifar da rashi na VII?
• Menene alamun alamun rashin ƙarfi na VII?
• Yaya aka gano raunin rashin VII?
• Yaya ake magance rashi kashi na VII?
• Kula da zubar jini
• Jiyya na yanayin asali
• Yin rigakafin kafin tiyata
• Menene hangen nesa na dogon lokaci?

Bayani

Rashin Factor VII cuta ce ta daskarewar jini wanda ke haifar da yawan jini ko tsawan lokaci bayan rauni ko tiyata. Tare da rashin ƙarancin VII, jikinka ko dai baya samar da isasshen factor VII, ko kuma wani abu yana tsangwama tare da dalilinka na VII, sau da yawa wani yanayin kiwon lafiya.

Factor VII shine furotin da aka samar a cikin hanta wanda ke taka muhimmiyar rawa wajen taimakawa jininka ya daskare. Yana daya daga cikin kusan abubuwa guda 20 da suka shafi daskarewa da jini. Don fahimtar rashin ƙarancin VII, yana taimakawa fahimtar rawar da VII ke takawa a cikin jini na al'ada.

Wace rawa factor VII ke takawa a dunkulewar jini na al'ada?

Tsarin jini na yau da kullun yana faruwa a matakai huɗu:

1. Maganin Vasoconstriction

Lokacin da aka yanke jijiyar jini, lalatacciyar jijiyar nan take takura don rage saurin zubar jini. Bayan haka, jijiyoyin jini da suka ji rauni suna fitar da furotin da ake kira factor factor a cikin jini. Sakin abubuwan nama yana yin kamar kiran SOS, yana nuna alamun jini da sauran abubuwan daskararre don ba da rahoto zuwa wurin raunin.

2. Samuwar faranti

Farantodi a cikin jini sune farkon wadanda suka isa wurin raunin. Sun haɗa kansu da kayan da aka lalata, da kuma ga juna, suna yin wucin gadi, toshe mai taushi a cikin rauni. Wannan tsari an san shi azaman hemostasis na farko.

3. Samuwar filastin fibrin

Da zarar fulogin na wucin gadi ya kasance, abubuwan da ke daskare jini suna bi ta wani hadadden sarkar abu don sakin fibrin, mai tauri, mai kirtani mai gina jiki. Fibrin na nade kanta a ciki da kewayen daskararren daskararren har sai ya zama taurin da ba zai iya narkewa ba. Wannan sabon gudan jini yana sanyawa mara buhun jini jini, kuma ya samar da kariya ta kariya ga sabbin cigaban nama.

4. Raunin rauni da lalata fulogin fibrin

Bayan fewan kwanaki, zaren fibrin ya fara raguwa, yana jan gefan ciwon tare don taimakawa sabon nama ya girma akan rauni. Yayinda aka sake sake kayan, daskararren fibrin ya narke kuma ya shanye.

Idan abu na VII baya aiki yadda yakamata, ko kuma akwai kadan daga ciki, to mafi ƙarfin fibrin ba zai iya yin daidai ba.

Menene ke haifar da rashi na VII?

Arancin Dalili na VII na iya zama na gado ko samu. Siffar da aka gada bata da yawa. Ba a daɗe da rahoton da aka yi rubuce rubuce a ƙasa da 200. Duk iyayenki dole ne su dauki kwayar halitta domin cutar ta same ku.

Abubuwan da aka samo rashi VII, akasin haka, yana faruwa bayan haihuwa. Hakan na iya faruwa sakamakon magunguna ko cututtukan da suke tsoma baki tare da dalilin ku na VII. Magunguna waɗanda zasu iya lalata ko rage aikin VII aiki sun haɗa da:

• maganin rigakafi
• masu kara jini, kamar warfarin
• wasu magungunan kansar, kamar su maganin interleukin-2
• maganin antithymocyte globulin wanda ake amfani dashi don magance cutar rashin jini

Cututtuka da yanayin kiwon lafiya waɗanda zasu iya tsoma baki tare da factor VII sun haɗa da:

• cutar hanta
• myeloma
• sepsis
• karancin jini
• rashi bitamin K

Menene alamun alamun rashin ƙarfi na VII?

Kwayar cutar ta bambanta daga m zuwa mai tsanani, gwargwadon matakanku na amfani mai amfani VII. Symptomsananan bayyanar cututtuka na iya haɗawa da:

• rauni da nama mai laushi
• tsawon lokacin jini daga raunuka ko hakorar haƙori
• zub da jini a gidajen abinci
• zubar hanci
• zubar da gumis
• lokacin al'ada mai nauyi

A cikin yanayi mafi tsanani, bayyanar cututtuka na iya haɗawa da:

• lalata guringuntsi a cikin gidajen abinci daga lokutan zub da jini
• zub da jini a cikin hanji, ciki, tsokoki, ko kai
• zubar jini mai yawa bayan haihuwa

Yaya aka gano raunin rashin VII?

Ganewar asali ya dogara ne akan tarihin lafiyar ku, kowane tarihin iyali na matsalolin zub da jini, da gwaje-gwajen gwaji.

Gwajin gwaje-gwaje don rashi na VII sun haɗa da:

• factor assays don gano abubuwan da suka ɓace ko rashin aiki
• factor VII gwajin don auna yawan nauyin VII da kuke da shi, da kuma yadda yake aiki
• lokacin prothrombin (PT) don auna aikin abubuwan I, II, V, VII, da X
• m prothrombin lokaci (PTT) don auna aiki na dalilai VIII, IX, XI, XII, da kuma von Willebrand dalilai
• mai hanawa gwaji don tantancewa idan tsarin garkuwar jikinka yana kawo hari ga abubuwan daskarewa

Yaya ake magance rashi kashi na VII?

Jiyya na rashin ƙarancin VII yana mai da hankali kan:

• sarrafa jini
• warware yanayin asali
• rigakafin magani kafin tiyata ko hanyoyin hakori

Kula da zubar jini

Yayin lokuta na zub da jini, ana iya ba ku infusions na abubuwan da ke tattare da jini don bunkasa ikon kuzarin ku. Ma'aikatan makirci waɗanda aka saba amfani da su sun haɗa da:

• hadadden prothrombin na mutum
• masarauta
• sabo ne da daskararren plasma
• recombinant mutum factor VIIa (NovoSeven)

Jiyya na yanayin asali

Da zarar jini yana gudana, dole ne a magance yanayin da ke lalata haɓakar VII ko aiki, kamar magunguna ko cututtuka.

Yin rigakafin kafin tiyata

Idan kuna shirin tiyata, likitanku na iya ba da magunguna don rage haɗarin zubar da jini da yawa. Desmopressin spray na hanci ana ba shi izini don sakin duk wadatattun shagunan na factor VII kafin ƙaramar tiyata. Don ƙarin tiyata mafi tsanani, likitanku na iya ba da umarnin yin amfani da ƙwayoyin cuta na ƙwayar cuta.

Menene hangen nesa na dogon lokaci?

Idan kana da nau'ikan da aka samu na rashi na VII, mai yiwuwa ya faru ne ta hanyar ko dai magunguna ko yanayin da ke ciki. Hannun ku na dogon lokaci ya dogara da gyara matsalolin. Idan kana da nau'ikan gado mafi tsananin wanda ke haifar da rashi na VII, zaka buƙaci yin aiki tare da likitanka da cibiyar hemophilia ta gida don kula da haɗarin zubar jini.