Mawallafi: Randy Alexander
Ranar Halitta: 24 Afrilu 2021
Sabuntawa: 19 Nuwamba 2024
Anonim
Pharmacology - Glucocorticoids
Video: Pharmacology - Glucocorticoids

Wadatacce

Bayani

Yawancin matsalolin kiwon lafiya sun haɗa da kumburi. Glucocorticoids suna da tasiri wajen dakatar da lalata kumburi wanda yawancin cututtukan garkuwar jiki ke haifarwa. Wadannan kwayoyi suna da sauran amfani da yawa. Koyaya, suma suna zuwa da sakamako masu illa. Waɗannan na iya zama mai tsanani, musamman idan ka yi amfani da waɗannan kwayoyi da tsayi.

Menene glucocorticoids?

Magungunan Glucocorticoid sune nau'ikan da mutum yayi na glucocorticoids, steroids wanda ke faruwa a jiki cikin jikinku. Suna da ayyuka da yawa. Isaya shine katse kumburi ta hanyar motsawa zuwa cikin ƙwayoyin cuta da kuma ɗanɗanar sunadaran da ke ci gaba don inganta kumburi. Hakanan suna taimaka wa jikinka amsawa ga damuwa da daidaita yadda jikinka ke amfani da mai da sukari.

Saboda glucocorticoids suna da ayyuka da yawa, an haɓaka mutum-mutum ko haɗin gwanin glucocorticoids don taimakawa wajen magance yanayi da yawa daban-daban.

Jerin magungunan glucocorticoid

Misalan magungunan glucocorticoid sun haɗa da:

  • akasarin
  • dankarinsone
  • budesonide
  • cortisone
  • dexamethasone
  • hydrocortisone
  • methylprednisolone
  • tsakar gida
  • prednisone
  • syeda_abubakar

Abin da glucocorticoids ke bi

Glucocorticoids na roba na iya zama masu ƙarfi fiye da yanayin da ke faruwa a cikin jikin mutum. Ana amfani dasu don magance yanayi da yawa.


Rashin lafiyar Autoimmune

Cututtukan cikin jiki na iya haifar da lalacewa mai yawa daga kumburi lokacin da jiki ya afka wa kansa da kuskure. Cututtuka na autoimmune sun hada da:

  • ƙwayar cuta mai yawa
  • rheumatoid amosanin gabbai
  • kumburi hanji cuta
  • ulcerative colitis
  • psoriasis
  • eczema

Glucocorticoids na iya rage yadda ƙwayoyin ƙwayoyin cuta ke aiki. Wannan yana taimakawa rage lalacewar cikin gida daga waɗannan cututtukan. Suna kawar da kumburi daga halayen autoimmune. Wannan na iya rage zafi, kumburi, matsewa, da ƙaiƙayi.

Allerji da asma

Allerji da asma yanayi ne wanda tsarin garkuwar ku yake amsa abubuwa mara cutarwa. A cikin waɗannan yanayin, abubuwa kamar su pollen ko gyada na iya haifar da mummunan tashin hankali mai kumburi. Kwayar cutar na iya bambanta kuma sun haɗa da:

  • ƙaiƙayi
  • idanun ido, idanun ruwa
  • rashin haske
  • ja, amya, ko kurji
  • atishawa da cushewa ko hanci
  • kumburin fuskarka, leɓɓa, ko maƙogwaro
  • matsalar numfashi

Glucocorticoids na iya magance wannan ɗaukar nauyin ta hanyar dakatar da kumburi da kwantar da hankulan ƙwayoyin cuta.


Rashin ƙarancin adrenal

Idan kuna da ƙarancin adrenal, jikinku ba zai iya samar da isasshen cortisol ba. Wannan na iya zama sakamakon wani yanayi kamar cutar Addison ko cirewar tiyatar adrenal gland. Glucocorticoids za'a iya amfani dashi don maye gurbin cortisol wanda jikinku bazai iya yin shi ba.

Ajiyar zuciya

Amfani na ɗan gajeren lokaci (ƙasa da kwanaki 7) na glucocorticoids na iya taimaka wajan magance raunin zuciya ta hanyar haɓaka ƙarfin jikinku don amsawa ga wasu masu diuretics. Koyaya, wannan ba amfani bane na yau da kullun.

Ciwon daji

Glucocorticoids za a iya amfani da shi wajen maganin cutar kansa don rage wasu illolin da ke tattare da cutar shan magani. Hakanan za'a iya amfani dasu don kashe wasu ƙwayoyin cutar kansa a cikin wasu cututtukan kansa, gami da:

  • m lymphoblastic cutar sankarar bargo
  • cutar sankarar bargo ta lymphoblastic
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
  • myeloma mai yawa

Yanayin fata

Yanayin fata wanda ya fara daga eczema zuwa guba mai guba ana bi da shi tare da glucocorticoids. Waɗannan sun haɗa da kan-da-kan-counter da kuma maganin shafawa na kanfani wanda kuke shafawa ga fata da magani da kuke sha ta bakinku.


Tiyata

Glucocorticoids ana iya amfani dashi yayin neurosurgeries masu mahimmanci. Suna rage kumburi a cikin m kyallen takarda. Ana kuma gudanar dasu kai tsaye bayan an sake dashen wani sashin jiki don taimakawa hana rigakafin garkuwar jiki da ƙin karɓar gudummawar.

Sakamakon sakamako

Glucocorticoids na iya yin kama da magungunan ƙwayoyi, amma suna da sakamako masu illa. Wasu daga cikin waɗannan tasirin na iya zama lahani sosai. Wannan shine dalilin da ya sa ba a ba da waɗannan magungunan ƙwayoyi don amfani na dogon lokaci ba.

Wadannan kwayoyi na iya:

  • kara yawan sukarin jininka, wanda zai iya haifar da ciwon suga na wani lokaci kuma mai yiwuwa
  • danne karfin jikin ku na shanye sinadarin calcium, wanda zai haifar da cutar sanyin kashi
  • kara yawan cholesterol da triglyceride
  • ƙara haɗarin ku na ulcers da gastritis
  • jinkirta warkar da rauni, wanda ke buƙatar adadin adadin kumburi
  • dankwafar da garkuwar jikinka da sanya ka mai saurin kamuwa da cututtuka

Yin amfani da glucocorticoids na dogon lokaci na iya haifar da asarar naman tsoka. Hakanan zai iya haifar da ciwo na Cushing, wanda zai haifar da:

  • wani abu mai ƙanshi tsakanin kafadunku
  • zagaye fuska
  • riba mai nauyi
  • ruwan hoda mai lankwasawa
  • kasusuwa kasusuwa
  • ciwon sukari
  • hawan jini
  • siraran fata
  • jinkirin warkarwa
  • kuraje
  • jinin al'ada
  • rage libido
  • gajiya
  • damuwa

Idan kun yi amfani da glucocorticoids fiye da 'yan makonni, likitanku zai iya shawo kan sashin ku a hankali maimakon ku daina shan shi gaba ɗaya. Wannan yana taimakawa don hana tasirin janyewa. Jikin ku yana sanya glucocorticoids, amma lokacin da kuka fara shan su azaman magani, jikin ku zaiyi tasiri ta hanyar rage shi da kansa. Lokacin da ka daina shan glucocorticoids, jikinka yana buƙatar lokaci don fara yin kansa a matakan al'ada.

Yi magana da likitanka

Glucocorticoids na iya zama magunguna masu amfani don magunguna daban-daban. Koyaya, yana da mahimmanci a daidaita buƙata don maganin glucocorticoid akan lahani. Idan likitanku ya ba da umarnin maganin glucocorticoid a gare ku, gaya musu game da duk wata illa da kuke da ita. Har ila yau yana da mahimmanci a ɗauki magunguna daidai yadda aka umurta, gami da lokacin da kuka daina su. Likitanku na iya yaye ku daga magungunan ku a hankali don hana janyewa.

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