Menene Sabo tare da Magungunan PPMS? Jagorar Bayanai

Wadatacce

• Binciken magunguna daga NINDS
• Magungunan warkewa
• Gyara abubuwa
• Shawarwarin gyarawa
• Jiki da bincike a cikin motsa jiki
• Noirƙirare-kirkire a cikin aikin sana'a
• Gwajin gwaji na PPMS
• Makomar maganin PPMS

Innovation a cikin Magungunan Sclerosis da yawa

Matsalar cutar sikandire ta farko (PPMS) ba ta da magani, amma akwai zaɓuɓɓuka da yawa don gudanar da yanayin. Jiyya yana mai da hankali kan sauƙaƙe bayyanar cututtuka yayin rage yiwuwar nakasa ta dindindin.

Dole likitan ku ya zama tushenku na farko don magance PPMS. Za su iya ba ku shawarwarin gudanarwa yayin da suke lura da ci gaban cutar.

Koyaya, har yanzu kuna da sha'awar bincika ƙarin albarkatu don maganin PPMS. Koyi game da damar anan.

Binciken magunguna daga NINDS

Cibiyar Nazarin Ciwon Lafiyar Jiji da Ciwan Gaji (NINDS) tana gudanar da bincike mai gudana a cikin kowane nau'i na ƙwayoyin cuta da yawa (MS).

NINDS reshe ne na Cibiyoyin Kiwon Lafiya na (asa (NIH), kuma tallafi daga gwamnati ke tallafawa. NINDS a halin yanzu tana binciken kwayoyi waɗanda zasu iya canza myelin da ƙwayoyin halitta waɗanda zasu iya hana farawar PPMS.

Magungunan warkewa

A cikin 2017, ocrelizumab (Ocrevus) ya sami izini daga Hukumar Abinci da Magunguna (FDA) don maganin PPMS da sake dawo da MS (RRMS). Wannan maganin injecti shine na farko kuma shine kawai magungunan PPMS akan kasuwa.

Dangane da NINDS, sauran kwayoyi a cikin ci gaba suma suna nuna alƙawari. Wadannan magungunan maganin zasuyi aiki ta hana kwayoyin myelin daga kumburi da juyawa zuwa rauni. Zasu iya kare ƙwayoyin myelin ko taimakawa gyara su bayan mummunan harin.

Maganin shan magani na baka (Mavenclad) shine irin wannan misalin.

Sauran magungunan da ake bincika suna iya haɓaka ci gaban oligodendrocytes. Oligodendrocytes sune takamaiman ƙwayoyin kwakwalwa waɗanda zasu taimaka wajen ƙirƙirar sabbin ƙwayoyin myelin.

Gyara abubuwa

Ba a san ainihin abin da ya haifar da PPMS - da kuma MS gaba ɗaya ba. Wani sashin kwayoyin ana tunanin zai taimaka wajen ci gaban cututtuka. Masu bincike suna ci gaba da nazarin tasirin kwayar halitta a cikin PPMS.

NINDS na nufin kwayoyin halittar da ka iya haifar da hadarin MS a matsayin “kwayoyin saukin kamuwa”. Isungiyar tana duba cikin magunguna waɗanda zasu iya gyara waɗannan ƙwayoyin halittar kafin MS ta haɓaka.

Shawarwarin gyarawa

Multiungiyar Multiple Sclerosis Society wata ƙungiya ce wacce ke ba da sabuntawa game da sababbin abubuwa a magani.

Ba kamar NINDS ba, Societyungiyar ungulu ce mai zaman kanta. Manufar su shine yada wayar da kan jama'a game da MS yayin da kuma tara kuɗi don tallafawa binciken likita.

A matsayin wani ɓangare na aikinta don tallafawa ba da haƙuri, Societyungiyar ta haɓaka sabunta albarkatun akan gidan yanar gizon ta. Saboda zaɓuɓɓukan ƙwayoyi suna iyakance, ƙila za ku sami albarkatun al'umma a kan tsarikan amfani. Anan suka tsara:

• gyaran jiki
• aikin likita
• gyaran fuska
• ilimin sana'a (na aiki)
• ilimin harshe na magana

Magunguna na jiki da na aikin aiki sune mafi yawan nau'ikan gyaran cikin PPMS. Mai zuwa wasu sabbin abubuwa ne na yau da kullun waɗanda suka shafi waɗannan hanyoyin kwantar da hankali guda biyu.

Jiki da bincike a cikin motsa jiki

Ana amfani da farfadowa na jiki (PT) azaman nau'in gyarawa a cikin PPMS. Manufofin PT na iya bambanta dangane da tsananin alamun cutar ku. An fi amfani dashi da farko:

• taimaka wa mutane da PPMS yin ayyukan yau da kullun
• karfafa 'yanci
• inganta aminci - alal misali, koyar da hanyoyin daidaita daidaito wanda zai iya rage haɗarin faɗuwa
• rage damar rashin lafiya
• ba da taimako na motsin rai
• ƙayyade buƙatar na'urorin tallafi a gida
• inganta yanayin rayuwa gabaɗaya

Likitanku zai iya ba da shawarar maganin jiki jim kaɗan bayan binciken ku na farko. Kasancewa mai himma game da wannan zaɓin maganin yana da mahimmanci - kar a jira har sai bayyanar cututtukanku ta ci gaba.

Motsa jiki wani muhimmin bangare ne na PT. Yana taimaka inganta motsi, ƙarfi, da kewayon motsi saboda haka zaka iya kiyaye independenceancin kai.

Har ila yau, masu bincike na ci gaba da duba fa'idodin aikin motsa jiki a cikin dukkan nau'ikan MS. A cewar National Multiple Sclerosis Society, ba a ba da shawarar motsa jiki sosai har zuwa tsakiyar 1990s. Wannan shi ne lokacin da ka'idar cewa motsa jiki ba shi da kyau ga MS a ƙarshe aka soke shi.

Kwararren likitanku na jiki zai iya ba da shawarar aikin motsa jiki wanda za ku iya yi - cikin aminci - tsakanin alƙawura don haɓaka alamunku da haɓaka ƙarfinku.

Noirƙirare-kirkire a cikin aikin sana'a

Ana ƙara fahimtar ilimin aikin sana'a azaman kadara a cikin maganin PPMS. Zai iya zama da amfani ga kulawa kai da aiki, kuma hakan ma zai iya taimakawa tare da:

• ayyukan hutu
• hutu
• zamantakewa
• aikin sa kai
• gudanar da gida

OT galibi ana tsinkaye kamar kasancewa ɗaya da PT. Kodayake waɗannan hanyoyin kwantar da hankalin sun dace da juna, kowannensu yana da alhakin bangarori daban-daban na maganin PPMS.

PT na iya tallafawa cikakken ƙarfin ku da motsi, kuma OT na iya taimakawa tare da ayyukan da suka shafi independenceancin ku, kamar wanka da yin ado da kan ku. An ba da shawarar cewa mutanen da ke tare da PPMS suna neman duka PT da kimantawar OT da magani na gaba.

Gwajin gwaji na PPMS

Hakanan zaka iya karanta game da magungunan PPMS na yanzu da masu zuwa a ClinicalTrials.gov. Wannan wani reshe ne na NIH. Manufar su ita ce samar da “rumbun adana bayanan karatun asibiti na kashin kansu da na jama'a da aka gudanar a duk duniya.”

Shigar da "PPMS" a cikin filin "Yanayin ko cuta". Za ku sami ɗimbin karatu masu aiki da kammala waɗanda suka shafi magunguna da sauran abubuwan da za su iya shafar cutar.

Bugu da ƙari, kuna iya yin la'akari da shiga cikin gwajin asibiti da kanku. Wannan babban sadaukarwa ne. Domin tabbatar da lafiyarku, yakamata ku tattauna gwajin likita tare da likitanku na farko.

Makomar maganin PPMS

Babu magani ga PPMS, kuma zaɓuɓɓukan magani suna iyakance. Har yanzu ana ci gaba da bincike don gano wasu ƙwayoyi ban da ocrelizumab wanda zai iya taimakawa sarrafa alamun ci gaba.

Baya ga dubawa tare da likitanku a kai a kai, yi amfani da waɗannan albarkatun don ci gaba da sanar da ku game da sabbin abubuwan sabuntawa tsakanin binciken PPMS. Ana yin aiki da yawa don ƙara fahimtar PPMS da kuma bi da mutane yadda ya kamata.