Kwayar cutar Parkinson's: Maza da Mata

Wadatacce

• Gabatar da bayyanar cututtuka
• Ikon tunani da motsi na tsoka
• Bayyanawa da fassara motsin rai
• Bambancin bacci
• Kariyar estrogen
• Matsalar magani
• Yin fama da PD

Cutar Parkinson a cikin maza da mata

Yawancin maza fiye da mata ana bincikar su da cutar ta Parkinson (PD) da kusan tazara 2 zuwa 1. Yawancin karatu suna tallafawa wannan lambar, gami da babban binciken a cikin Jaridar American Epidemiology.

Yawancin lokaci akwai dalilin ilimin lissafi na bambancin cuta tsakanin maza da mata. Ta yaya kasancewa mace tana kariya daga PD? Kuma shin mata da maza suna fuskantar alamun PD daban?

Gabatar da bayyanar cututtuka

Mata suna haɓaka PD ƙasa da sau fiye da yadda maza suke yi. Lokacin da suka inganta PD, shekarun farawa shine shekaru biyu baya fiye da maza.

Lokacin da aka fara gano mata, rawar jiki yawanci ita ce babbar alama. Alamar farko a cikin maza yawanci sannu a hankali ko motsi mara ƙarfi (bradykinesia).

Yanayin PD mai girgizar ƙasa yana da alaƙa da saurin ci gaba da cuta da ingancin rayuwa.

Koyaya, mata galibi suna bayar da rahoton rashin gamsuwa da ƙimar rayuwarsu, koda tare da irin wannan matakin alamun.

Ikon tunani da motsi na tsoka

PD na iya shafar ikon tunani da azanci har da sarrafa tsoka.

Akwai wasu shaidun cewa maza da mata suna shafar daban. Misali, maza suna bayyana cewa suna riƙe da kyakkyawan ikon fahimtar yanayin sararin samaniya. Mata, a gefe guda, suna riƙe da karin magana.

Wadannan nau'ikan ƙwarewar suna tasiri ba kawai ta hanyar jima'i ba, har ma da “gefen” alamun PD. Hagu na hagu ko gefen hagu na alamun motsawar farko yana nuna wane gefen kwakwalwa ne ke da rashi mafi girma na dopamine.

Misali, zaka iya samun matsala tare da sarrafa tsoka a bangaren hagu na jikinka idan kana da karancin kwayar dopamine a bangaren dama na kwakwalwarka.

Dabaru daban-daban, kamar su damar sararin samaniya, sun fi rinjaye akan takamaiman ɓangaren kwakwalwa.

Bayyanawa da fassara motsin rai

Rigimar PD na iya sa tsokokin fuska su “daskare.” Wannan yana haifar da magana irin ta mask. A sakamakon haka, marasa lafiya da PD suna da wahalar bayyana motsin rai tare da fuskokinsu. Hakanan zasu iya fara samun matsala wajen fassara yanayin fuskokin wasu.

Wani bincike ya nuna cewa maza da mata masu cutar PD na iya fuskantar wahalar fassara fushi da mamaki, kuma maza suna iya rasa ikon fassara tsoro.

Koyaya, mata na iya zama mafi damuwa da rashin iya fassarar motsin rai. Duk marasa lafiyar PD na iya cin gajiyar magana da gyaran jiki don taimakawa da wannan alamar.

Bambancin bacci

Rashin saurin halayyar motsa ido (RBD) cuta ce ta bacci wanda ke faruwa yayin REM bacci na sake zagayowar.

A yadda aka saba, mutum mai bacci ba shi da ƙwayar tsoka kuma baya motsi yayin bacci. A cikin RBD, mutum na iya motsa gabobi da alama suna aiwatar da mafarkinsu.

RBD yana faruwa da ƙyar, amma sau da yawa a cikin mutane da cututtukan neurodegenerative. Kimanin kashi 15 cikin 100 na mutanen da ke da PD suma suna da RBD, a cewar Binciken Cikin gida na Ilimin halin ƙwaƙwalwa. Maza sun fi mata samun wannan matsalar.

Kariyar estrogen

Me yasa akwai bambance-bambance a cikin alamun PD tsakanin maza da mata? Da alama alama ce kasancewar isrogen yana kare mata daga wani ci gaban PD.

Wani binciken da aka buga a cikin binciken ya nuna cewa matar da ta gamu da al'adar daga baya, ko kuma tana da yara da yawa, akwai yiwuwar ta jinkirta fara bayyanar cutar ta PD. Waɗannan duka alamomi ne na bayyanarwar estrogen tsawon rayuwarta.

Abinda ba'a gama bayyana shi ba shine dalilin da yasa estrogen yake da wannan tasirin. Wani bincike da aka yi a mujallar tabin hankali ta Amurka ya nuna cewa mata suna da wadatar dopamine a mahimman wurare na ƙwaƙwalwa. Estrogen na iya aiki azaman neuroprotectant don aikin dopamine.

Matsalar magani

Mata masu cutar PD na iya fuskantar ƙarin matsaloli yayin maganin alamun su na PD fiye da maza.

Mata na karbar tiyata kasa da sau fiye da yadda maza ke yi, kuma alamominsu sun fi tsanani a lokacin da za a yi musu tiyata. Hakanan, ci gaban da aka samu daga tiyata na iya zama ba mai girma ba.

Magunguna don magance alamun PD na iya shafar mata daban. Saboda ƙananan nauyin jiki, mata galibi suna fuskantar haɗarin magunguna masu yawa. Wannan ya kasance matsala tare da levodopa, ɗayan magunguna mafi mahimmanci ga PD.

Haɗuwa mafi girma na iya haifar da ƙara ƙimar mummunan sakamako, kamar dyskinesia. Dyskinesia yana da wahalar yin motsi na son rai.

Yin fama da PD

Maza da mata galibi suna da martani daban-daban game da kwarewar rayuwa tare da PD.

Mata masu cutar PD suna fuskantar tsananin baƙin ciki fiye da maza masu cutar PD. Sabili da haka suna karɓar magungunan antidepressant sau da yawa.

Maza na iya samun ƙarin matsaloli na ɗabi'a da tsokanar zalunci, kamar haɗarin yawo da rashin dacewa ko halayen cin zarafi. Maza sun fi saurin karɓar magungunan ƙwaƙwalwa don magance wannan ɗabi'ar.