Tunƙarar Stromal na Tashin Ciki: Cutar cututtuka, Dalili, da Abubuwan Haɗari

Wadatacce

• Kwayar cututtuka
• Dalilin
• Hanyoyin haɗari
• Shekaru
• Kwayoyin halitta

Ciwon cututtukan cututtukan ciki na ciki (GISTs) sune ciwace-ciwace, ko gungu-ƙwayoyin ƙwayoyin cuta, a cikin ɓangaren hanji (GI). Kwayar cututtukan cututtukan GIST sun hada da:

• kujerun jini
• zafi ko rashin jin daɗi a cikin ciki
• tashin zuciya da amai
• toshewar hanji
• taro a ciki wanda zaka ji
• gajiya ko jin kasala sosai
• jin cikakken abinci bayan cin ƙananan abubuwa
• zafi ko wahala yayin haɗiyewa

Yankin GI shine tsarin da ke da alhakin narkewa da shayar da abinci da abubuwan gina jiki. Ya hada da esophagus, ciki, karamin hanji, da kuma hanji.

GISTs suna farawa a cikin ƙwayoyin musamman waɗanda ke cikin ɓangaren tsarin juyayi mai sarrafa kansa. Waɗannan ƙwayoyin suna cikin bangon yankin GI, kuma suna tsara motsi na tsoka don narkewa.

Yawancin GISTs suna cikin ciki. Wani lokacin sukan yi girma a cikin karamar hanji, amma GISTs da ke samu a cikin hanji, esophagus, da dubura ba su da yawa. GIST na iya zama kodai madogara da cutar kansa ko mara kyau kuma ba ta cutar kansa ba.

Kwayar cututtuka

Alamomin cutar sun dogara da girman kumburin da kuma inda yake. Saboda wannan, galibi suna bambanta cikin tsanani kuma daga mutum ɗaya zuwa wancan. Kwayar cututtuka irin su ciwon ciki, tashin zuciya, da gajiya sun haɗu da wasu yanayi da cututtuka da yawa.

Idan kana fuskantar ɗayan waɗannan ko wasu alamomin da ba na al'ada ba, ya kamata ka yi magana da likitanka. Zasu taimaka wajen gano dalilin alamunku.

Idan kana da wasu abubuwan haɗari ga GIST ko wani yanayin da zai iya haifar da waɗannan alamun, tabbas ka ambaci hakan ga likitanka.

Dalilin

Ba a san ainihin dalilin GISTs ba, kodayake akwai alama akwai alaƙa da maye gurbi a cikin bayanin furotin na KIT. Ciwon daji yana tasowa lokacin da ƙwayoyin halitta suka fara girma daga cikin iko. Yayinda kwayoyin ke ci gaba da girma ba da tsari ba, suna ginawa don samar da wani abu da ake kira ƙari.

GISTs suna farawa a cikin hanyar GI kuma suna iya haɓaka zuwa cikin tsari ko gabobin da ke kusa. Suna yaduwa akai-akai zuwa hanta da kuma peritoneum (rufin membranous na ramin ciki) amma da wuya zuwa lymph nodes kusa.

Hanyoyin haɗari

Akwai sanannun sanannun abubuwan haɗari ga GISTs:

Shekaru

Mafi yawan shekarun da ake samun ci gaban GIST shine tsakanin 50 da 80. Duk da yake GIST na iya faruwa a cikin mutanen da basu kai shekaru 40 ba, suna da ƙarancin gaske.

Kwayoyin halitta

Yawancin GISTs suna faruwa bazuwar kuma basu da wani dalili mai ma'ana. Koyaya, ana haifar wasu mutane da maye gurbi wanda zai iya haifar da GISTs.

Wasu daga cikin kwayoyin halitta da yanayin da ke hade da GIST sun haɗa da:

Neurofibromatosis 1: Wannan cuta ta kwayar halitta, wanda kuma ake kira cutar Von Recklinghausen (VRD), ya samo asali ne daga lahani a cikin NF1 kwayar halitta Ana iya daukar cutar daga iyaye zuwa yaro amma ba koyaushe ake gado ba. Mutanen da ke da wannan yanayin suna cikin haɗarin haɗari don haɓaka ciwace-ciwace marasa amfani a cikin jijiyoyi tun suna kanana. Wadannan ciwace-ciwacen na iya haifar da tabo mai duhu akan fata da freckling a cikin makwancin gwaiwa ko ƙananan kango. Hakanan wannan yanayin yana ƙara haɗarin haɓaka GIST.

Iyalin cututtukan cututtukan ciki na ciki na ciki: Wannan cututtukan yana haifar da mafi yawancin lokuta ta hanyar ƙwayar cuta ta KIT da ba ta dace ba daga iyaye zuwa yaro. Wannan yanayin da ba safai yake faruwa ba yana ƙara haɗarin GISTs. Wadannan GISTs na iya ƙirƙirar da ƙuruciya fiye da yawan jama'a. Mutane masu wannan yanayin na iya samun GIST da yawa yayin rayuwarsu.

Maye gurbi a cikin kwayar halittar dehydrogenase (SDH) kwayoyin halitta: Mutanen da aka haifa tare da maye gurbi a cikin kwayoyin SDHB da SDHC suna cikin haɗarin haɓaka GISTs. Hakanan suna cikin haɗarin haɗari don haɓaka wani nau'in ƙwayar jijiya wanda ake kira paraganglioma.