Magungunan Antiplatelet - Masu hanawa P2Y12

Platelets wasu kananan kwayoyin halitta ne a cikin jininka wanda jikinka yake amfani dasu wajen samarda daskarewa da tsaida zubar jini. Idan yawan platelet dinka yayi yawa ko kuma platelet dinka suna haduwa sosai, da alama zaka iya yin daskarewa. Wannan daskararren na iya faruwa a cikin jijiyoyin ka kuma zai iya haifar da bugun zuciya ko bugun jini.

Magungunan Antiplatelet suna aiki don sanya platelet ɗinku suyi ƙaranci kuma ta haka zasu taimaka hana yaduwar jini daga yin jijiyoyin ku.

• Asfirin magani ne na maganin hana haifuwa wanda za'a iya amfani dashi.
• Masu hana karɓa na P2Y12 wasu rukuni ne na magungunan antiplatelet. Wannan rukuni na magunguna sun haɗa da: clopidogrel, ticlopidine, ticagrelor, prasugrel, da cangrelor.

Ana iya amfani da magungunan antiplatelet don:

• Hana bugun zuciya ko bugun jini ga waɗanda ke da PAD.
• Clopidogrel (Plavix, generic) ana iya amfani dashi a madadin asfirin ga mutanen da ke da rawanin jijiyoyin jijiyoyin jiki ko kuma waɗanda aka saka wani abu.
• Wasu lokuta ana ba da magunguna guda biyu (ɗayansu kusan ko da yaushe asfirin) don mutanen da ke fama da cutar angina, cututtukan jijiyoyin zuciya (rashin angina ko alamun farko na bugun zuciya), ko waɗanda suka sami ƙarfi a lokacin PCI.
• Game da cututtukan zuciya na rigakafin farko da na sakandare, asfirin na yau da kullun shine farkon zaɓi na maganin antiplatelet. Clopidogrel an sanya shi maimakon asfirin ga mutanen da suke da rashin lafiyar asfirin ko kuma wadanda ba za su iya jurewa asfirin ba.
• Aspirin da magani na antiplatelet na biyu galibi ana ba da shawarar ne ga mutanen da ke shan cutar angioplasty tare da ko ba tare da ɗorawa ba.
• Hana ko magance cututtukan zuciya.
• Tsayar da bugun jini ko saurin kai tsaye (TIAs alamun gargaɗi ne na saurin bugun jini. Ana kuma kiransu "mini-shanyewar jiki.")
• Hana daskarewa daga yin ciki a cikin jijiyoyin da aka sa a jijiyoyin ku don bude su.
• Ciwon cututtukan zuciya.
• Bayan tiyatar dasawa wanda ke amfani da dasasshen mutum ko aikin roba da aka yi akan jijiyoyin da ke ƙasa da gwiwa.

Mai ba ku kiwon lafiya zai zaɓi wane ɗayan waɗannan ƙwayoyi ne mafi kyau don matsalar ku. A wasu lokuta, ana iya tambayarka ka sha aspirin ƙarami tare da ɗayan waɗannan magungunan.

Sakamakon sakamako na wannan magani na iya haɗawa da:

• Gudawa
• Itching
• Ciwan
• Rushewar fata
• Ciwon ciki

Kafin ka fara shan waɗannan magunguna, gaya wa mai baka idan:

• Kuna da matsalolin zub da jini ko gyambon ciki.
• Kuna da ciki, shirya yin ciki, ko kuna shayarwa.

Akwai wasu sauran sakamako masu illa, gwargwadon wane magani aka ba ku. Misali:

• Ticlopidine na iya haifar da ƙarancin ƙarancin ƙwayoyin jini ko rashin lafiyar da ke lalata platelets.
• Ticagrelor na iya haifar da alamun gajeren numfashi.

Ana shan wannan maganin azaman kwaya. Mai ba da sabis ɗinku na iya canza yawan ku daga lokaci zuwa lokaci.

Thisauki wannan magani tare da abinci da ruwa mai yawa don rage tasirin. Kila buƙatar dakatar da shan clopidogrel kafin a fara tiyata ko aikin hakori. Kada kawai ka daina shan magungunan ka ba tare da fara magana da mai baka ba.

Yi magana da mai ba da sabis kafin shan ɗayan waɗannan ƙwayoyin:

• Heparin da sauran masu yankan jini, kamar warfarin (Coumadin)
• Jin zafi ko maganin amosanin gabbai (kamar diclofenac, etodolac, ibuprofen, indomethacin, Advil, Aleve, Daypro, Dolobid, Feldene, Indocin, Motrin, Orudis, Relafen, ko Voltaren)
• Phenytoin (Dilantin), tamoxifen (Nolvadex, Soltamox), tolbutamide (Orinase), ko kuma torsemide (Demadex)

Kar ka ɗauki wasu ƙwayoyi waɗanda zasu iya samun aspirin ko ibuprofen a cikin su kafin yin magana da mai baka. Karanta alamomin akan magungunan sanyi da mura. Tambayi waɗanne magunguna ne lafiyayyu domin ku sha don ciwo da ciwo, mura, ko mura.

Idan kana da kowane irin tsari da aka tsara, zaka iya buƙatar dakatar da waɗannan ƙwayoyin kwanaki 5 zuwa 7 kafin hannunka. Koyaya, koyaushe bincika mai ba ku sabis da farko game da ko lafiya zai iya tsayawa.

Faɗa wa mai ba ka idan kana da ciki ko kuma shirin yin ciki, ko shayarwa ko shirin shayarwa. Mata a matakan baya na ciki kada su sha clopidogrel. Clopidogrel na iya yaduwa ga jarirai ta madarar nono.

Yi magana da mai baka idan kana da cutar hanta ko koda.

Idan ka rasa kashi:

• Itauke shi da wuri-wuri, sai dai idan lokacin yin aikin ku ne na gaba.
• Idan lokaci ne na maganin ku na gaba, ɗauki adadin ku na yau da kullun.
• Kar a ɗauki ƙarin ƙwayoyi don biyan kuɗin da aka rasa, sai dai idan likitanku ya gaya muku.

Ajiye waɗannan magungunan da duk sauran magunguna a wuri mai sanyi, bushe. Rike su inda yara ba zasu iya zuwa wurin su ba.

Kira idan kuna da ɗayan waɗannan tasirin kuma ba zasu tafi ba:

• Duk wasu alamu na zub da jini ba sani ba sabo, kamar jini a cikin fitsari ko kujeru, zubar jini, duk wani rauni da ba a saba gani ba, zub da jini mai yawa daga yankewa, kujerun baƙar fata, zubar jini, wanda ya fi jinin al'ada al'ada ko zubar jini na farji, amai wanda yake kama da kofi
• Dizziness
• Matsalar haɗiyewa
• Nessarfafawa a kirji ko ciwon kirji
• Kumburi a fuskarka ko hannunka
• Chingaiƙai, amya, ko ƙwanƙwasawa a fuskarka ko hannayenku
• Kuzari ko wahalar numfashi
• Ciwon ciki mai tsananin gaske
• Rushewar fata

Ragewar jini - clopidogrel; Antiplatelet far - clopidogrel; Takamatsu

• Ginin allo a cikin jijiyoyin jini

Ibrahim NS, Hlatky MA, Antman EM, et al. ACCF / ACG / AHA 2010 takaddar masaniyar yarjejeniya game da amfani da kwayoyi masu hana motsa jiki da kuma masu amfani da kwayoyi: ingantaccen bayani game da yarjejeniyar ƙwararrun masanan ACCF / ACG / AHA 2008 akan rage haɗarin ciki na maganin antiplatelet da amfani NSAID: rahoton rahoton Kungiyar Foundationungiyar Foundationungiyar Amincewa da iowararrun Americanwararrun Americanwararrun Americanwararrun Americanwararrun onwararru ta Amurka. J Am Coll Cardiol. 2010; 56 (24): 2051-2066. PMID: 21126648 pubmed.ncbi.nlm.nih.gov/21126648/.

Fihn SD, Blankenship JC, Alexander KP, et al. 2014 ACC / AHA / AATS / PCNA / SCAI / STS sun ƙaddamar da sabuntawa game da jagora don ganewar asali da kula da marasa lafiya tare da kwanciyar hankali na cututtukan zuciya: rahoto na Kwalejin Kwalejin Zuciya ta Amurka / Heartungiyar Heartungiyar Heartungiyar Zuciya ta Amurka kan Sharuɗɗan Aiki, da Americanungiyar (asar Amirka game da Tiyata Thoracic, Nungiyar Magunguna na Nakasassu na Jiji, Angungiyar Kula da Magungunan Zuciya da Ayyuka, da ofungiyar Likitocin Thoracic Kewaya. 2014; 130: 1749-1767. PMID: 25070666 pubmed.ncbi.nlm.nih.gov/25070666/.

Goldstein LB. Rigakafin da kula da cutar ischemic. A cikin: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald na Ciwon Zuciya: Littafin rubutu na Magungunan zuciya da jijiyoyin jini. 11th ed. Philadelphia, PA: Elsevier; 2019: sura 65.

Janairu CT, Wann LS, Alpert JS, et al. Jagoran 2014 AHA / ACC / HRS don kula da marasa lafiya tare da ɓarna: rahoton rahoton kwalejin cututtukan zuciya na Amurka / Heartungiyar Heartungiyar Heartungiyar Zuciya ta Amurka game da Ka'idodin Ayyuka da Rungiyar Zuciya. J Am Coll Cardiol. 2014; 64 (21): e1-e76. PMID: 24685669 pubmed.ncbi.nlm.nih.gov/24685669/.

Mauri L, Bhatt DL. Hanyar shiga cikin jijiyoyin jini. A cikin: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald na Ciwon Zuciya: Littafin rubutu na Magungunan zuciya da jijiyoyin jini. 11th ed. Philadelphia, PA: Elsevier; 2019: babi na 62.

Meschia JF, Bushnell C, Boden-Albala B, et al. Sharuɗɗa don rigakafin farko na bugun jini: sanarwa ga ƙwararrun likitocin kiwon lafiya daga Heartungiyar Zuciya ta Amurka / Stungiyar Baƙin Amurka. Buguwa. 2014; 45 (12): 3754-3832. PMID: 25355838 pubmed.ncbi.nlm.nih.gov/25355838/.

Morrow DA, de Lemos JA. Ciwon cututtukan zuciya na ischemic. A cikin: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald na Ciwon Zuciya: Littafin rubutu na Magungunan zuciya da jijiyoyin jini. 11th ed. Philadelphia, PA: Elsevier; 2019: babi na 61.

Ersarfin WJ, Rabinstein AA, Ackerson T, et al. Sharuɗɗa don kulawar farko na marasa lafiya da cutar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar nan a 2019 a 2019. Buguwa. 2019; 50 (12): e344-e418. PMID: 31662037 pubmed.ncbi.nlm.nih.gov/31662037/.

• Angina
• Angioplasty da stent jeri - carotid jijiya
• Angioplasty da stent jeri - gefe jijiyoyin jini
• Yin aikin tiyata na bawul - mai saurin cin zali
• Tiyata bawul aortic - bude
• Tsarin cirewar zuciya
• Yin aikin tiyata na Carotid - a buɗe
• Ciwon cututtukan huhu na ƙarshe (COPD)
• Ciwon zuciya
• Yin aikin tiyata na zuciya
• Yin aikin tiyata na zuciya - mara haɗari
• Ajiyar zuciya
• Mai bugun zuciya
• Matakan ƙwayar cholesterol na jini
• Hawan jini - manya
• Gyarawa mai juyawa-defibrillator
• Yin tiyata bawul na mitral - ƙananan haɗari
• Yin aikin tiyata na mitral - a buɗe
• Kewayen jijiyoyin kai - kafa
• Ciwon jijiyoyin jijiyoyin jiki - kafafu

• Angina - fitarwa
• Angioplasty da mai ƙarfi - zuciya - fitarwa
• Angioplasty da stent jeri - carotid jijiya - fitarwa
• Angioplasty da stent jeri - arteries na gefe - fitarwa
• Asfirin da cututtukan zuciya
• Atrial fibrillation - fitarwa
• Yin aiki lokacin da kake da cututtukan zuciya
• Cardiac catheterization - fitarwa
• Yin aikin tiyata na Carotid - fitarwa
• Kula da hawan jini
• Ciwon sukari - hana ciwon zuciya da bugun jini
• Ciwon zuciya - fitarwa
• Yin aikin tiyata na zuciya - fitarwa
• Yin tiyata ta zuciya - fitina kaɗan - fitarwa
• Rashin zuciya - fitarwa
• Tiyata bawul na zuciya - fitarwa
• Kewayen jijiyoyin kai - fitarwa - kafa - fitarwa
• Bugun jini - fitarwa

• Jinin Jini