Ciwon Klinefelter

Cutar Klinefelter wani yanayi ne na kwayar halitta wanda ke faruwa ga maza yayin da suke da ƙarin X chromosome.

Yawancin mutane suna da 46 chromosomes. Chromosomes suna dauke da dukkanin kwayoyin halittar ku da DNA, tubalin ginin jiki. Hanyoyin chromosomes na 2 (X da Y) suna yanke hukunci idan kun zama saurayi ko yarinya. Yan mata suna da chromosomes 2 X. Yara maza suna da 1 X da 1 Y chromosome.

Klinefelter ciwo yana haifar da lokacin da aka haifi ɗa tare da aƙalla 1 ƙarin X chromosome. An rubuta wannan azaman XXY.

Cutar Klinefelter tana faruwa kusan 1 daga cikin yara 500 zuwa 1,000 yara maza. Matan da suke samun ciki bayan sun kai shekaru 35 suna iya samun ɗa namiji da wannan ciwo fiye da ƙananan mata.

Rashin haihuwa shine mafi yawan alamun cututtukan Klinefelter.

Kwayar cutar na iya haɗawa da ɗayan masu zuwa:

• Abubuwan da ba na al'ada ba (dogayen ƙafa, gajere gajere, kafada daidai da girman ƙugu)
• Babban ƙananan nono (gynecomastia)
• Rashin haihuwa
• Matsalolin jima'i
• Kasa da adadin al'ada na al'ada, hamata, da gashin fuska
• Ananan, ƙwayayyun ƙwayoyin cuta
• Tsawon tsayi
• Sizeananan girman azzakari
  
  

Za a iya fara gano cutar ta Klinefelter lokacin da wani mutum ya zo wurin mai kula da lafiya saboda rashin haihuwa. Za a iya yin gwaje-gwaje masu zuwa:

• Karyotyping (yana bincikar chromosomes)
• Yawan maniyyi

Za a yi gwajin jini don bincika matakan hormone, gami da:

• Estradiol, wani nau'in estrogen ne
• Tsarin hormone mai motsa jiki
• Luteinizing hormone
• Testosterone

Ana iya tsara maganin testosterone. Wannan na iya taimakawa:

• Girma gashi jiki
• Inganta bayyanar tsokoki
• Inganta maida hankali
• Inganta yanayi da girman kai
• Energyara kuzari da motsa sha'awa
• Strengthara ƙarfi

Mafi yawan maza masu wannan ciwo ba sa iya ɗaukar mace ciki. Kwararren likita game da rashin haihuwa zai iya taimakawa. Ganin likita da ake kira endocrinologist na iya zama da taimako.

Waɗannan kafofin na iya samar da ƙarin bayani game da cututtukan Klinefelter:

• Ungiyar don bambancin X da Y Chromosome - genetic.org
• Laburaren Magunguna na Kasa, Maganar Gidajen Gida - medlineplus.gov/klinefelterssyndrome.html

Teethananan hakora tare da siraran ƙasa suna da yawa a cikin cututtukan Klinefelter. Wannan shi ake kira taurodontism. Ana iya ganin wannan a kan x-haskoki na hakori.

Ciwon Klinefelter kuma yana ƙara haɗarin:

• Rashin kulawar cututtukan cututtuka (ADHD)
• Rashin lafiyar kansa, kamar lupus, rheumatoid arthritis, da ciwo na Sjögren
• Ciwon nono a cikin maza
• Bacin rai
• Illolin karatu, gami da cutar dyslexia, wanda ya shafi karatu
• Wani nau'in ciwo mai mahimmanci wanda ake kira ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta
• Cutar huhu
• Osteoporosis
• Magungunan varicose

Tuntuɓi mai ba da sabis idan ɗanka ba ya haɓaka halaye na jima'i na biyu lokacin balaga. Wannan ya hada da girman gashin fuska da zurfin murya.

Mai ba da shawara kan kwayar halitta za ta iya ba da bayani game da wannan yanayin kuma ya umurce ka da ka tallafa wa ƙungiyoyi a yankinka.

47 Ciwon X-X-Y; XXY ciwo; XXY trisomy; 47, XXY / 46, XY; Ciwon Mosaic; Poly-X Klinefelter ciwo

Allan CA, McLachlan RI. Cutar rashin lafiyar androgen. A cikin: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Manya da Yara. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 139.

Matsumoto AM, Anawalt BD, Rikicin gwaji. A cikin: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Littafin Williams na Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: babi na 19.

Nussbaum RL, McInnes RR, Willard HF. Kwayar halittar chromosomal da asalin halittar cuta: rikicewar yanayin rashin daidaito da kuma chromosomes na jima'i. A cikin: Nussbaum RL, McInnes RR, Willard HF, eds. Thompson & Thompson Genetics a Magunguna. 8th ed. Philadelphia, PA: Elsevier; 2016: babi na 6.