Ciwon Cutar Cushing

Ciwon kumburin kumburi wani nau'i ne na ciwon Cushing wanda ƙari a wajen gland shine yake samar da hormone da ake kira hormone adrenocorticotropic (ACTH).

Cutar ciwo ta Cushing cuta ce da ke faruwa yayin da jikinka ya sami matakin da ya fi na al'ada na hormone cortisol. Wannan hormone ana yin sa ne a cikin gland adrenal. Cortisol da yawa na iya zama saboda matsaloli daban-daban. Ofaya daga cikin dalilan shine idan akwai yawan hormone ACTH a cikin jini. ACTH yawanci pituitary ne ke yin sa sannan kuma yana sigina ga gland don samar da cortisol. Wasu lokuta wasu kwayoyin a wajen pituitary na iya yin yawancin ACTH. Wannan shi ake kira ectopic Cushing syndrome. Mahimmin ciki yana nufin cewa wani abu yana faruwa a wani wuri mara kyau a cikin jiki.

Ciwan Ectopic Cushing yana faruwa ne sakamakon ciwan da yake saki ACTH. Tumorin da zasu iya, a cikin wasu ƙananan lamura, su saki ACTH sun haɗa da:

• Ignananan ƙwayoyin cuta na huhu
• Orsanƙarar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta
• Carcinoma na Medullary na thyroid
• Cellananan ƙwayoyin cuta na huhu
• Umumfari na ƙwanƙasar ciki

Ciwon Cutar Cushin Cushing na iya haifar da alamomi daban-daban. Wasu mutane suna da alamomi da yawa yayin da wasu ke da kaɗan. Yawancin mutane da kowane irin ciwo na Cushing suna da:

• Zagaye, ja, da cikakken fuska (fuskar wata)
• Saurin girma cikin yara
• Rage nauyi tare da tara kitse a jikin akwati, amma asarar mai daga hannu, kafafu, da gindi (tsakiyar kiba)

Canje-canje na fata waɗanda ake yawan gani:

• Cututtukan fata
• Alamar madaidaiciya mai tsayi (inci 1/2 inci 1 ko mafi faɗi) da ake kira striae akan fatar ciki, cinyoyi, hannuwan hannu na sama, da ƙirjin
• Fata mai laushi tare da raunin rauni

Muscle da kashi canje-canje sun hada da:

• Ciwon baya, wanda ke faruwa tare da ayyukan yau da kullun
• Ciwon ƙashi ko taushi
• Tarin kitse tsakanin kafadu da sama da abin wuya
• Rib da kasusuwa na kashin baya wanda aka samu sakamakon siririn kasusuwa
• Musclesarfin tsokoki, musamman na kwatangwalo da kafaɗu

Matsalolin jiki (na tsari) na iya haɗawa da:

• Rubuta ciwon sukari na 2
• Hawan jini
• Babban cholesterol da triglycerides
  

Mata na iya samun:

• Ci gaban gashi da yawa a fuska, wuya, kirji, ciki, da cinyoyi
• Lokutan da suka zama marasa tsari ko tsayawa

Maza na iya samun:

• Rage ko babu sha'awar yin jima'i
• Rashin ƙarfi

Sauran cututtukan da za su iya faruwa sun haɗa da:

• Canje-canjen tunani, kamar ɓacin rai, damuwa, ko canje-canje a ɗabi'a
• Gajiya
• Ciwon kai
• Thirstarin ƙishirwa da fitsari

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya yi tambaya game da alamunku.

Gwajin da za a iya yi sun hada da:

• Samfurin fitsari na awa 24 don auna matakan cortisol da na halitta
• Gwajin jini don bincika ACTH, cortisol, da matakan potassium (sau da yawa ƙarancin ciwo na Cushing na ectopic)
• Dexamethasone danniya gwajin (duka biyu high da low kashi)
• Samfurin sinus na ƙananan ƙwayar cuta (gwaji na musamman wanda ke auna ACTH daga jijiyoyin kusa da kwakwalwa da kuma kirji)
• Azumin glucose
• MRI da babban ƙuduri na CT suna bincika ƙwayar cuta (wani lokacin ana iya buƙatar sikanin nukiliya)

Mafi kyaun magani don ciwon kumburin kuzari shine tiyata don cire kumburin. Yin aikin tiyata yawanci yana yiwuwa yayin da ƙari ba shi da matsala (mara kyau).

A wasu lokuta, ciwon na sankarar kansa ne kuma ya bazu zuwa wasu sassan jiki kafin likita ya gano matsalar samar da cortisol. Yin aikin tiyata bazai yiwu a waɗannan yanayin ba. Amma likita na iya rubuta magunguna don toshe kayan cortisol.

Wasu lokuta ana buƙatar cire duka glandon adrenal idan ba za a iya samun kumburin ba kuma magunguna ba su toshe kayan cortisol.

Yin aikin tiyata don cire ƙwayar cuta na iya haifar da cikakken dawowa. Amma akwai damar cewa ƙari zai dawo.

Ciwon zai iya yaduwa ko dawowa bayan tiyata. Babban matakin cortisol na iya ci gaba.

Kira mai ba ku sabis idan kun ci gaba da alamun cutar Cushing.

Gaggauta lura da ciwace-ciwace na iya rage haɗarin a wasu yanayi. Yawancin lokuta ba a hana su.

Ciwon Cushing - mahaifa; Ciwon mara na ACTH

• Endocrine gland

Nieman LK, Biller BM, Findling JW, et al. Jiyya na ciwo na Cushing: jagorar aikin likita na Endocrine Society. J Clin Endocrinol Metab. 2015; 100 (8): 2807-2831. PMID 26222757 www.ncbi.nlm.nih.gov/pubmed/26222757.

Stewart PM, Newell-Price JDC. Tsarin adrenal. A cikin: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Littafin Williams na Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: babi na 15.