Lupus erythematosus da ke haifar da ƙwayoyi

Lupus erythematosus da ke haifar da ƙwayoyi cuta ce ta rashin lafiyar jiki wanda ke haifar da amsa ga magani.

Lupus erythematosus da ke haifar da ƙwayoyi iri ɗaya ne amma ba su yi daidai da tsarin lupus erythematosus ba (SLE). Cutar rashin lafiya ce. Wannan yana nufin jikinka ya afka wa lafiyayyen nama bisa kuskure. Hakan na faruwa ne ta hanyar wani magani. Yanayi masu alaƙa sune cututtukan cututtukan fata da ke haifar da kwayar cutar da kwayar cutar ta ANCA vasculitis.

Magungunan da aka fi sani dasu suna haifar da lupus erythematosus da ke haifar da ƙwayoyi sune:

• Isoniazid
• Hydralazine
• Procainamide
• Tumor-necrosis factor (TNF) masu hana alpha (kamar etanercept, infliximab da adalimumab)
• Minocycline
• Quinidine

Sauran kwayoyi marasa mahimmanci na iya haifar da yanayin. Waɗannan na iya haɗawa da:

• Magungunan rigakafi
• Capoten
• Chlorpromazine
• Methyldopa
• Sulfasalazine
• Levamisole, yawanci azaman gurɓataccen hodar iblis

Magungunan rigakafin rigakafin kansa kamar pembrolizumab kuma na iya haifar da wasu nau'ikan halayen motsa jiki ciki har da cutar lupus da ke sa ƙwayoyi.

Kwayar cututtukan cututtukan ƙwayoyin cuta na lupus suna faruwa bayan shan magani don aƙalla watanni 3 zuwa 6.

Kwayar cutar na iya haɗawa da:

• Zazzaɓi
• Jin ciwo na musamman (rashin lafiyar jiki)
• Hadin gwiwa
• Kumburin hadin gwiwa
• Rashin ci
• Jin zafi na kirji
• Rushewar fata akan wuraren da hasken rana ya shafa

Mai ba da sabis na kiwon lafiya zai yi gwajin jiki kuma ya saurari kirjinku tare da stethoscope. Mai ba da sabis ɗin na iya jin wani sauti da ake kira ruɓanin gogewar zuciya ko shafawar gogewar juji.

Binciken fata yana nuna kurji.

Abubuwan haɗin gwiwa na iya zama kumbura da taushi.

Gwajin da za a iya yi sun hada da:

• Antihistone antibody
• Antinuclear antibody (ANA) panel
• Antineutrophil cytoplasmic antibody (ANCA) panel
  
• Kammala ƙididdigar jini (CBC) tare da bambanci
• Cikakken kwamitin sunadarai
• Fitsari

X-ray na kirji na iya nuna alamun pleuritis ko pericarditis (kumburi kewaye da rufin huhu ko zuciya). ECG na iya nuna cewa zuciya ta kamu.

Mafi yawan lokuta, bayyanar cututtuka suna tafiya tsakanin withinan kwanaki da makonni bayan dakatar da maganin da ya haifar da yanayin.

Jiyya na iya haɗawa da:

• Magungunan rigakafin cututtukan ƙwayoyin cuta (NSAIDs) don magance cututtukan zuciya da haɓaka
• Man shafawa na 'Corticosteroid creams' don magance kumburin fata
• Magungunan antimalarial (hydroxychloroquine) don magance alamomin fata da amosanin gabbai

Idan yanayin yana shafar zuciyar ka, koda, ko tsarin juyayi, za'a iya rubuta maka babban allurar corticosteroids (prednisone, methylprednisolone) da masu hana garkuwar jiki (azathioprine ko cyclophosphamide). Wannan ba safai bane.

Lokacin da cutar ke aiki, ya kamata ku sa tufafin kariya da tabarau don kiyaye rana da yawa.

Mafi yawan lokuta, lupus erythematosus da ke haifar da ƙwayoyi ba ta da ƙarfi kamar SLE. Alamomin cutar sukan gushe cikin 'yan kwanaki zuwa makonni bayan tsayar da maganin da kuke sha. Ba da daɗewa ba, kumburin koda (nephritis) na iya haɓaka tare da cutar lupus da ƙwaya ta haifar ta masu hana ta TNF ko tare da kwayar cutar ta ANCA saboda hydralazine ko levamisole. Ciwon ƙwayar ƙwayar ƙwayar cuta na iya buƙatar magani tare da prednisone da magungunan rigakafi.

Guji shan magani wanda ya haifar da tasirin a nan gaba. Alamomin na iya dawowa idan kayi haka.

Matsaloli na iya haɗawa da:

• Kamuwa da cuta
• Thrombocytopenia purpura - zub da jini kusa da farfajiyar fata, sakamakon ƙarancin adadin jini a cikin jini
• Anaemia mai raunin jini
• Ciwon ciki
• Ciwon mara
• Ciwon mara

Kira mai ba da sabis idan:

• Kuna haɓaka sababbin bayyanar cututtuka lokacin shan kowane magani da aka lissafa a sama.
• Alamun ku ba sa samun sauki bayan kun daina shan maganin da ya haifar da cutar.

Kula da alamun amsa idan kana shan wasu magungunan da zasu iya haifar da wannan matsalar.

Lupus - miyagun ƙwayoyi ya haifar

• Lupus, discoid - ra'ayi na raunuka akan kirji
• Antibodies

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Dooley MA. Lupus da ke haifar da ƙwayoyi A cikin: Tsokos GC, ed. Tsarin Lupus Erythematosus. Cambridge, MA: Elsevier Makarantar Ilimin; 2016: babi na 54.

Radhakrishnan J, Perazella MA. Cutar cututtukan glomerular da ke haifar da ƙwayoyi: ana buƙatar hankali! Clin J Am Soc Nephrol. 2015; 10 (7): 1287-1290. PMID: 25876771 www.ncbi.nlm.nih.gov/pubmed/25876771.

Richardson BC. Lupus da ke haifar da ƙwayoyi A cikin: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: sura 141.

Rubin RL. Lupus da ke haifar da ƙwayoyi Gwani Opin Drug Saf. 2015; 14 (3): 361-378. PMID: 25554102 www.ncbi.nlm.nih.gov/pubmed/25554102.

Vaglio A, Grayson PC, Fenaroli P, et al. Lupus da ke haifar da ƙwayoyi: al'adun gargajiya da sabbin abubuwa. Autoimmun Rev.. 2018; 17 (9): 912-918. PMID: 30005854 www.ncbi.nlm.nih.gov/pubmed/30005854.