Tsarin jini na thrombotic thrombocytopenic

Thrombotic thrombocytopenic purpura (TTP) cuta ce ta jini wanda a ciki ƙwarjin jini yake zama a cikin ƙananan jijiyoyin jini. Wannan yana haifar da ƙarancin ƙarancin platelet (thrombocytopenia).

Wannan cuta na iya faruwa ta hanyar matsaloli tare da enzyme (wani nau'in furotin) wanda ke da hannu cikin daskarewar jini. Ana kiran wannan enzyme ADAMTS13. Rashin wannan enzyme yana haifar da dunƙulewar platelet. Platelets wani bangare ne na jini wanda ke taimakawa wajen daskarewar jini.

Yayinda platelets ke dunkulewa wuri daya, ana samun karancin platelet a cikin jini a wasu sassan jiki don taimakawa da daskarewa. Wannan na iya haifar da zub da jini a karkashin fata.

A wasu lokuta, cutar na yaduwa ne ta hanyar dangi (wadanda aka gada). A waɗannan yanayin, ana haihuwar mutane da ƙananan matakan wannan enzyme.

Wannan yanayin kuma na iya faruwa ta hanyar:

• Ciwon daji
• Chemotherapy
• Hematopoietic kara cell dasawa
• Cutar HIV
• Maganin maye gurbin Hormone da estrogens
• Magunguna (gami da ticlopidine, clopidogrel, quinine, da cyclosporine A)

Kwayar cutar na iya haɗawa da ɗayan masu zuwa:

• Zuban jini a cikin fatar jiki ko na gamsai
• Rikicewa
• Gajiya, rauni
• Zazzaɓi
• Ciwon kai
• Launin launi mai launi ko launin fata mai launin rawaya
• Rashin numfashi
• Saurin zuciya (sama da 100 a kowane minti)

Gwajin da za'a iya yin oda sun hada da:

• ADAMTS 13 matakin aiki
• Bilirubin
• Shafar jini
• Kammala ƙididdigar jini (CBC)
• Matsayin halittar
• Matsaran Lactate dehydrogenase (LDH)
• Countididdigar platelet
• Fitsari
• Haptoglobin
• Gwajin kabo

Wataƙila kuna da magani wanda ake kira musayar plasma. Yana cire plasma mara kyau kuma ya maye gurbin shi da plasma na al'ada daga mai bayarwa mai lafiya. Plasma wani sashi ne na jini wanda yake dauke da kwayoyin jini da platelets. Musayar Plasma shima yana maye gurbin enzyme da ya ɓace.

Ana yin aikin kamar haka:

• Na farko, an zana jininka kamar ba da jini.
• Yayinda jini ke ratsawa ta cikin na’urar da ta raba jini zuwa bangarorinsa daban-daban, sai a cire ruwan jini mara kyau kuma a ceci jininku.
• Daga nan sai a hada ƙwayoyin jininku tare da ruwan jini na yau da kullun daga mai bayarwa, sannan a sake ba ku.

Ana maimaita wannan magani kowace rana har sai gwajin jini ya nuna inganta.

Mutanen da ba su amsa wannan magani ba ko kuma yanayin da suke dawowa sau da yawa na iya buƙatar:

• Yi tiyata don cire ƙwayoyinsu
• Samo magungunan da ke dankwafar da garkuwar jiki, kamar su steroids ko rituximab

Mafi yawan mutanen da suke shan musayar plasma suna warkewa gaba ɗaya. Amma wasu mutane suna mutuwa ta wannan cutar, musamman idan ba a gano ta ba nan take. A cikin mutanen da ba su warke ba, wannan yanayin na iya zama na dogon lokaci (na kullum).

Matsaloli na iya haɗawa da:

• Rashin koda
• Plateananan ƙarancin platelet (thrombocytopenia)
• Countananan ƙwayar ƙwayar jinin jini (wanda ya faru sanadiyyar lalacewar ƙwayoyin jinin jini da wuri)
• Matsalolin tsarin jijiya
• Zubar jini mai tsanani (zubar jini)
• Buguwa

Kira wa likitan lafiyar ku idan kuna da wani zubar jini da ba a bayyana ba.

Saboda ba a san musabbabin hakan ba, babu wata hanyar sananniya da za a iya hana wannan yanayin.

TTP

• Kwayoyin jini

Abrams CS. Kwayoyin cuta. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: babi na 172.

Cibiyar Zuciya ta Kasa, huhu, da gidan yanar gizo. Tsarin jini na thrombotic thrombocytopenic. www.nhlbi.nih.gov/health-topics/thrombotic-thrombocytopenic-purpura. An shiga Maris 1, 2019.

Schneidewend R, Epperla N, Friedman KD. Tsarin thrombotic thrombocytopenic purpura da cututtukan uremic na uremic. A cikin: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Ka'idoji da Aiki. 7th ed. Philadelphia, PA: Elsevier; 2018: babi na 134.