Takayasu arteritis

Takayasu arteritis cuta ce ta manyan jijiyoyi kamar su aorta da manyan rassa. Aorta shine jijiyar da take daukar jini daga zuciya zuwa ga sauran jiki.

Ba a san dalilin Takayasu arteritis ba. Cutar ta fi faruwa ne galibi yara da mata tsakanin shekara 20 zuwa 40. Ya fi kamari ne ga mutanen yankin Asiya ta Gabas, Indiya ko Meziko. Koyaya, yanzu ana ganinta sau da yawa a wasu sassan duniya. Yawancin kwayoyin halitta wadanda ke kara damar samun wannan matsalar ba da dadewa ba.

Takayasu arteritis ya zama yanayin rashin lafiyar kansa. Wannan yana nufin tsarin garkuwar jiki yayi kuskuren afkawa da lafiyayyen nama a bangon jirgin jini. Halin na iya haɗawa da sauran tsarin gabobin.

Wannan yanayin yana da fasali da yawa waɗanda suke kama da katuwar kwayar halitta ta arteritis ko kuma lokacin arteritis a cikin tsofaffi.

Kwayar cutar na iya haɗawa da:

• Weaknessarfin hannu ko ciwo tare da amfani
• Ciwon kirji
• Dizziness
• Gajiya
• Zazzaɓi
• Haskewar kai
• Muscle ko haɗin gwiwa
• Rushewar fata
• Zufar dare
• Gani ya canza
• Rage nauyi
• Rage bugun radial (a wuyan hannu)
• Bambancin karfin jini tsakanin hannayen biyu
• Hawan jini (hauhawar jini)

Hakanan akwai alamun alamun ƙonewa (pericarditis ko pleuritis).

Yiwuwar gwaje-gwaje sun haɗa da:

• Angiogram, gami da jijiyoyin jini
• Kammala ƙididdigar jini (CBC)
• Furotin C-mai amsawa (CRP)
• Lantarki (ECG)
• Erythrocyte sedimentation kudi (ESR)
• Magnetic fuska angiography (MRA)
• Hanyoyin fuska ta maganadisu (MRI)
• Ididdigar yanayin halittar hoto (CTA)
• Positron watsi tomography (PET)
• Duban dan tayi
• X-ray na kirji

Maganin Takayasu arteritis yana da wahala. Koyaya, mutanen da suke da maganin da ya dace na iya inganta. Yana da mahimmanci a gano yanayin da wuri. Cutar na daɗa kasancewa mai ɗorewa, yana buƙatar amfani da magungunan anti-inflammatory na dogon lokaci.

MAGUNGUNA

Yawancin mutane ana fara jin su da babban ƙwayoyin corticosteroids kamar su prednisone. Yayinda ake shawo kan cutar an rage karfin prednisone.

A kusan dukkan lamura, ana kara magungunan rigakafi don rage yawan bukatar amfani da prednisone na dogon lokaci amma duk da haka kula da cutar.

Ana ƙara yawan wakilan masu hana rigakafin rigakafi irin su methotrexate, azathioprine, mycophenolate, cyclophosphamide, ko leflunomide.

Hakanan wakilan halittu na iya zama masu tasiri. Waɗannan sun haɗa da masu hanawa na TNF kamar su infliximab, etanercept, da tocilizumab.

Tiyata

Za a iya amfani da tiyata ko angioplasty don buɗe ƙunƙuntattun jijiyoyi don bayar da jini ko buɗe ƙuntatawa.

Ana iya buƙatar sauya bawul na aortic a wasu yanayi.

Wannan cuta na iya zama ajali ba tare da magani ba. Koyaya, haɗakarwa ta hanyar amfani da magunguna da tiyata ya rage ƙimar mutuwa. Manya suna da kyakkyawar damar rayuwa fiye da yara.

Matsaloli na iya haɗawa da:

• Rage jini
• Ciwon zuciya
• Ajiyar zuciya
• Ciwon mara
• Rashin isasshen ƙarfin bawul
• Ciwon ciki
• Buguwa
• Zubar da cikin ciki ko ciwo daga toshewar jijiyoyin jijiyoyin jini

Kira mai ba da sabis na kiwon lafiya idan kuna da alamun wannan yanayin. Ana buƙatar kulawa ta gaggawa idan kana da:

• Rashin ƙarfi
• Ciwon kirji
• Matsalar numfashi

Cutar rashin kuzari, Babban jirgin ruwa vasculitis

• Zuciya - sashi ta tsakiya
• Bawul na zuciya - hangen nesa
• Bawul na zuciya - ingantaccen ra'ayi

Alomari I, Patel PM. Takayasu arteritis. A cikin: Ferri FF, ed. Ferri's Clinical Advisor 2020. Philadelphia, PA: Elsevier; 2020: 1342.e4-1342.e7.

Barra L, Yang G, Pagnoux C; Cibiyar Sadarwar Vasculitis ta Kanada (CanVasc). Magungunan marasa-glucocorticoid don maganin cutar arteritis na Takayasu: Nazarin tsari da meta-bincike. Autoimmun Rev.. 2018; 17 (7): 683-693. PMID: 29729444 pubmed.ncbi.nlm.nih.gov/29729444/.

Dejaco C, Ramiro S, Duftner C, et al. EULAR shawarwari don amfani da hoto a cikin babban jirgin ruwa vasculitis a cikin aikin likita. Ann Rheum Dis. 2018; 77 (5): 636-643. PMID: 29358285 pubmed.ncbi.nlm.nih.gov/29358285/.

Ehlert BA, Abularrage CJ. Cutar Takayasu. A cikin: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery da Endovascular Far. 9th ed. Philadelphia, PA: Elsevier; 2019: sura 139.

Serra R, Butrico L, Fugetto F, et al. Sabuntawa a cikin ilimin cututtukan zuciya, ganewar asali da kuma kula da Takayasu arteritis. Ann Vasc Surg. 2016; 35: 210-225. PMID: 27238990 pubmed.ncbi.nlm.nih.gov/27238990/.