Rashin zaɓin IgA

Rashin zaɓin IgA shine cuta mafi ƙarancin cuta. Mutanen da ke fama da wannan cuta suna da ƙarancin sunadarin jinin da ake kira immunoglobulin A.

Rashin ƙarancin IgA yawanci ana gado ne, wanda ke nufin an wuce shi ta wurin iyalai. Koyaya, akwai kuma lokuta na rashin ƙarancin IgA.

Ana iya gado azaman ikon mallaka na autosomal ko yanayin ƙoshin kansa. Mafi yawanci ana samunta ne a cikin mutanen asalin Turai. Ba kasafai ake samun hakan ba ga mutanen wasu ƙabilun.

Mutane da yawa da ke fama da karancin IgA ba su da wata alama.

Idan mutum yana da alamun cututtuka, zasu iya haɗawa da lokuta masu yawa na:

• Bronchitis (ƙwayar iska)
• Ciwon mara na kullum
• Conjunctivitis (ciwon ido)
• Inflammationonewar ciki, ciki har da ulcerative colitis, cututtukan Crohn, da cuta mai kama da cuta
• Ciwon baki
• Otitis media (ciwon kunne na tsakiya)
• Ciwon huhu (huhu kamuwa da cuta)
• Sinusitis (sinus kamuwa da cuta)
• Cututtukan fata
• Manyan cututtukan fili na numfashi

Sauran cututtukan sun hada da:

• Bronchiectasis (wata cuta ce wacce ƙaramar jakar iska a cikin huhu ke lalacewa kuma ta faɗaɗa)
• Asma ba tare da sanannen sanadi ba

Zai yiwu a sami tarihin iyali na rashin IgA. Gwajin da za a iya yi sun hada da:

• IgG ƙananan ma'auni
• Yawan immunoglobulins
• Maganin rigakafin rigakafi

Babu takamaiman magani. Wasu mutane suna haɓaka matakan IgA na al'ada ba tare da magani ba.

Yin jiyya ya haɗa da ɗaukar matakai don rage lamba da tsananin kamuwa da cuta. Sau da yawa ana buƙatar maganin rigakafi don magance cututtukan ƙwayoyin cuta.

Ana ba da rigakafin immunoglobulins ta wata jijiya ko ta hanyar allura don ƙarfafa garkuwar jiki.

Maganin cututtukan autoimmune ya dogara da takamaiman matsala.

Lura: Mutanen da ke da cikakkiyar rashi na IgA na iya haifar da ƙwayoyin rigakafin-IgA idan aka ba su kayan jini da na immunoglobulins. Wannan na iya haifar da rashin lafiyar jiki ko barazanar rai mai sa rai. Koyaya, ana iya basu cikin aminci a cikin IgA wanda ya kare immunoglobulins.

Rashin zaɓin IgA ba shi da cutarwa fiye da sauran cututtukan rashin ƙarancin cuta.

Wasu mutanen da ke da rashi na IgA za su murmure da kansu kuma su samar da IgA cikin adadi mai yawa na tsawon shekaru.

Rashin ƙwayar cuta irin su cututtukan zuciya na rheumatoid, tsarin lupus erythematosus, da kuma celiac sprue na iya ci gaba.

Mutanen da ke da rashi na IgA na iya haifar da ƙwayoyin cuta ga IgA. A sakamakon haka, suna iya yin mummunan aiki, har ma da barazanar rai ga ƙarin jini da kayayyakin jini.

Idan kana da rashi na IgA, tabbatar ka ambace shi ga mai ba ka kiwon lafiya idan an ba da shawarar immunoglobulin ko wasu ƙarin abubuwan da ke cikin jini a matsayin magani ga kowane irin yanayi.

Bayar da shawara game da kwayar halitta na iya zama da ƙima ga iyaye masu zuwa tare da tarihin iyali na zaɓin karancin IgA.

Rashin IgA; Immunodepressed - IgA rashi; Immunosuppressed - IgA rashi; Hypogammaglobulinemia - Rashin IgA; Agammaglobulinemia - Rashin raunin IgA

• Antibodies

Cunningham-Rundles C. Cutar cututtukan rashin ƙarfi na farko. A cikin: Goldman L, Schafer AI, eds. Magungunan Goldman-Cecil. 26th ed. Philadelphia, PA: Elsevier; 2020: babi na 236.

Sullivan KE, Buckley RH. Laifin farko na samar da sinadarin antibody. A cikin: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Littafin koyar da ilimin yara. 21st ed. Philadelphia, PA: Elsevier; 2020: babi na 150.