Antinuclear antibody panel

Bankin antiinuclear antibody panel gwajin jini ne wanda yake kallon kwayoyi masu kare sinadarin (ANA).

ANA sunadarai ne da aka samar da su ta hanyar garkuwar jiki wadanda ke daure wa kwayoyin halittar jiki. Gwajin kwayar cutar antinuclear yana neman kwayoyin cuta wadanda suka daure zuwa wani sel wanda ake kira tsakiya. Gwajin gwaji yana tantance ko irin waɗannan ƙwayoyin cuta suna nan. Har ila yau, gwajin yana auna matakin, wanda ake kira titer, da tsarin, wanda zai iya taimakawa. Idan gwajin ya tabbatacce, ana iya yin gwajin gwaji don gano takamaiman abubuwan antigen. Wannan shine kwamitin ANA.

Ana ɗauke jini daga jijiya. Mafi yawanci, ana amfani da jijiya a cikin gwiwar gwiwar hannu ko bayan hannu. An tsabtace shafin da maganin kashe kwayoyin cuta (antiseptic). Mai ba da kiwon lafiyar ya nade ɗamarar roba a hannu na sama don matsa lamba ga yankin kuma ya sa jijiyar ta kumbura da jini.

Na gaba, mai bayarwa a hankali yana saka allura a cikin jijiya. Jinin yana tattarawa a cikin bututun iska ko kuma bututun da ke haɗe da allurar. An cire bandin na roba daga hannunka.

Da zarar an debi jinin, sai a cire allurar, sannan a rufe wurin huda don dakatar da duk wani jini.

A cikin jarirai ko ƙananan yara, ana iya amfani da kaifi mai mahimmanci wanda ake kira lancet don huda fata kuma ya sa jini ya zama jini. Jinin yana tattarawa a cikin ƙaramin bututun gilashi da ake kira bututu, ko kan silaid ko tsiri gwajin. Za'a iya sanya bandeji akan wurin idan akwai zubar jini.

Dogaro da dakin gwaje-gwaje, ana iya sarrafa gwajin ta hanyoyi daban-daban. Wata hanya tana buƙatar mai fasaha don bincika samfurin jini a ƙarƙashin microscope ta amfani da hasken ultraviolet. Ɗayan yana amfani da kayan aiki na atomatik don yin rikodin sakamakon.

Ba a buƙatar shiri na musamman. Koyaya, wasu kwayoyi, gami da magungunan hana haihuwa, procainamide, da thiazide diuretics, suna tasiri daidaito na wannan gwajin. Tabbatar cewa mai ba da sabis ya san game da duk magungunan da kuka sha.

Lokacin da aka saka allurar don zana jini, wasu mutane suna jin matsakaicin ciwo. Wasu kuma ba sa jin wani abu kamar harbawa ko wani abu mai zafi. Bayan haka, ana iya samun wasu buguwa.

Kuna iya buƙatar wannan gwajin idan kuna da alamun rashin lafiyar jiki, musamman tsarin lupus erythematosus. Ana iya yin wannan gwajin idan kuna da alamun da ba a bayyana ba kamar su arthritis, rashes, ko ciwon kirji.

Wasu mutane na al'ada suna da ƙananan matakin ANA. Don haka, kasancewar ƙaramin matakin ANA ba koyaushe bane al'ada.

An ruwaito ANA a matsayin "titer". Titananan titers suna cikin zangon 1:40 zuwa 1:60. Gwajin ANA mai kyau shine mafi mahimmanci idan kuna da kwayoyi akan jikin DNA mai daure biyu.

Kasancewar ANA ba ya tabbatar da ganewar asali na cutar lupus erythematosus (SLE). Koyaya, rashin ANA yana sa wannan ganewar ta ragu sosai.

Kodayake yawanci ana gano ANA tare da SLE, gwajin ANA mai kyau na iya zama alamar wasu cututtukan autoimmune.

Jeri na darajar yau da kullun na iya ɗan bambanta kaɗan tsakanin ɗakunan gwaje-gwaje daban-daban. Yi magana da mai baka game da ma'anar takamaiman sakamakon gwajin ka.

Misalan da ke sama suna nuna ma'aunai gama gari don sakamako ga waɗannan gwaje-gwajen. Wasu dakunan gwaje-gwaje suna amfani da ma'aunai daban-daban ko na iya gwada samfuran daban.

Testsarin gwaje-gwaje na iya gudana akan jini tare da gwajin ANA mai kyau don samun ƙarin bayani.

Don yin ganewar asali na SLE, wasu sifofin asibiti gami da ANA dole ne su kasance. Bugu da kari, wasu takamaiman kwayoyin ANA na taimakawa don tabbatar da cutar.

Kasancewar ANA cikin jini na iya zama saboda wasu rikice-rikice da yawa banda SLE. Wadannan sun hada da:

CUTUTTUKA AUTOIMMUNE

• Cakuda cututtukan nama mai hade
• Lupus erythematosus da ke haifar da ƙwayoyi
• Myositis (cututtukan tsoka mai kumburi)
• Rheumatoid amosanin gabbai
• Ciwon Sjögren
• Tsarin sclerosis (scleroderma)
• Ciwon thyroid
• Autoimmune hepatitis
• Lymphomas

CUTUTTUKA

• Cutar EB
• Ciwon hanta C
• HIV
• Parvovirus

Jijiyoyi da jijiyoyin jini sun bambanta da girma daga mutum ɗaya zuwa wancan, kuma daga wannan gefe na jiki zuwa wancan. Samun jini daga wasu mutane na iya zama da wahala fiye da wasu.

Sauran haɗarin da ke tattare da ɗaukar jinni ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Hematoma (jini yana taruwa a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

Mai ba da sabis ɗinku zai yi amfani da sakamakon rukunin ANA don taimakawa yin ganewar asali. Kusan duk mutanen da ke da SLE masu aiki suna da ANA mai kyau. Koyaya, tabbataccen ANA da kanta bai isa yayi bincike na SLE ko wata cuta ta autoimmune ba. Dole ne a yi amfani da gwajin ANA tare da tarihin lafiyar ku, gwajin jiki da sauran gwaje-gwajen gwaje-gwaje.

ANA na iya zama mai kyau a cikin dangin mutane tare da SLE waɗanda ba su da SLE da kansu.

Akwai ƙaramar dama don haɓaka SLE a wani lokaci daga baya a rayuwa idan abin da kawai aka gano shine ƙaramin matakin ANA.

ANA; Kwamitin ANA; NAungiyar ANA mai fa'ida; SLE - ANA; Tsarin lupus erythematosus - ANA

• Gwajin jini

Alberto von Mühlen C, Fritzler MJ, Chan EKL. Bincike na asibiti da dakin gwaje-gwaje na cututtukan rheumatic. A cikin: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Hanyoyin Laboratory. 23 ga ed. St Louis, MO: Elsevier; 2017: babi na 52.

Kwalejin Kwalejin Rheumatology ta Amurka. Antinuclear antibodies (ANA). www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Condition/Antinuclear-Antibodies-ANA. An sabunta Maris 2017. An shiga Afrilu 04, 2019.

Reeves WH, Zhuang H, Han S. Autoantibodies a cikin tsarin lupus erythematosus. A cikin: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: sura 139.