Maganin globulin electrophoresis

Gwajin serum globulin electrophoresis yana auna matakan sunadaran da ake kira globulins a bangaren ruwa na samfurin jini. Wannan ruwa shi ake kira serum.

Ana bukatar samfurin jini.

A cikin dakin gwaje-gwaje, ma'aikacin ya sanya samfurin jini akan takarda ta musamman kuma ya yi amfani da wutar lantarki. Sunadaran suna motsawa akan takarda kuma suna yin makada wadanda suke nuna adadin kowace sunadarin.

Bi umarnin kan ko kuna buƙatar yin azumi kafin wannan gwajin.

Wasu magunguna na iya shafar sakamakon wannan gwajin. Mai ba ku kiwon lafiya zai gaya muku idan kuna buƙatar dakatar da shan kowane magani. Kada ka dakatar da kowane magani kafin magana da mai baka.

Lokacin da aka saka allurar don zana jini, wasu mutane suna jin matsakaicin ciwo. Wasu kuma suna jin ƙyalli ko harba. Bayan haka, ƙila za a sami wasu harbi ko ɗan rauni. Wannan da sannu zai tafi.

Ana yin wannan gwajin ne don duba sunadaran globulin da ke cikin jini. Gano nau'ikan globulins na iya taimakawa wajen gano wasu matsalolin likita.

Globulins sun kasu kashi uku: alpha, beta, da gamma globulins. Gamma globulins sun hada da nau'ikan kwayoyin cuta kamar su immunoglobulins (Ig) M, G, da A.

Wasu cututtukan suna haɗuwa da samar da yawancin immunoglobulins. Misali, Waldenstrom macroglobulinemia ciwon daji ne na wasu farin ƙwayoyin jini. Yana da alaƙa da samar da ƙwayoyin cuta na IgM da yawa.

Jeri masu darajar al'ada sune:

• Serum globulin: 2.0 zuwa 3.5 gram a kowace deciliter (g / dL) ko kuma gram 20 zuwa 35 a kowace lita (g / L)
• Bangaren IgM: milligram 75 zuwa 300 a cikin mai yankewa (mg / dL) ko kuma 750 zuwa 3,000 milligram a kowace lita (mg / L)
• Bangaren IgG: 650 zuwa 1,850 mg / dL ko 6.5 zuwa 18.50 g / L.
• Bangaren IgA: 90 zuwa 350 mg / dL ko 900 zuwa 3,500 mg / L

Jeri na darajar yau da kullun na iya ɗan bambanta kaɗan tsakanin ɗakunan gwaje-gwaje daban-daban. Wasu leburori suna amfani da ma'auni daban daban ko gwada samfuran daban. Yi magana da mai baka game da ma'anar takamaiman sakamakon gwajin ka.

Karin sunadaran gamma globulin na iya nuna:

• M kamuwa da cuta
• Ciwon jijiyoyin jini da na kasusuwa ciki har da myeloma mai yawa, da wasu kwayoyin cuta da cutar sankarar bargo
• Rikicin rashi rigakafi
• Ciwon kumburi na dogon lokaci (alaƙa) (alal misali, cututtukan rheumatoid da tsarin lupus erythematosus)
• Waldenström macroglobulinemia

Akwai haɗarin haɗari kaɗan tare da ɗaukar jininka. Jijiyoyi da jijiyoyin jini sun bambanta da girma daga mutum ɗaya zuwa wancan, kuma daga wannan gefe na jiki zuwa wancan. Bloodaukar jini daga wasu mutane na iya zama da wahala fiye da wasu.

Sauran haɗarin da ke tattare da ɗaukar jinni ba su da yawa, amma na iya haɗawa da:

• Zub da jini mai yawa
• Sumewa ko jin an sassauta kai
• Mahara huda don gano wuri jijiyoyinmu
• Hematoma (haɓakar jini a ƙarƙashin fata)
• Kamuwa (ƙananan haɗari kowane lokaci fata ta karye)

Yawan immunoglobulins

• Gwajin jini

Chernecky CC, Berger BJ. Immunoelectrophoresis - magani da fitsari. A cikin: Chernecky CC, Berger BJ, eds. Gwajin Laboratory da hanyoyin bincike. Na 6 ed. St Louis, MO: Elsevier Saunders; 2013: 667-692.

Dominiczak MH, Fraser WD. Jini da sunadaran plasma. A cikin: Baynes JW, Dominiczak MH, eds. Magungunan Biochemistry. 5th ed. Philadelphia, PA: Elsevier; 2019: sura 40.